Splanchnic hyposensitivity to glypressin in a haemorrhage/transfused rat model of portal hypertension: Role of nitric oxide and bradykinin

Clinical Science

Volumn 99, Issue 6, 2000, Pages 475-482

  Chu, C J ^a   Wu, S L ^a   Lee, F Y ^a   Wang, S S ^a   Chang, F Y ^a   Lin, H C ^a   Chan, C C ^a   Lee, S D ^a  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Bradykinin; Glypressin; Haemorrhage; Hyposensitivity; Nitric oxide; Portal hypertension

Indexed keywords

BRADYKININ; CANAVANINE; ICATIBANT; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; TERLIPRESSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLEEDING; BLOOD PRESSURE REGULATION; CARDIOVASCULAR AUTOREGULATION; CONTROLLED STUDY; DRUG POTENTIATION; HEMODYNAMICS; HUMAN; MALE; PORTAL HYPERTENSION; PRIORITY JOURNAL; RAT; SPLANCHNIC BLOOD FLOW; TRANSFUSION;

ANIMALS; BLOOD PRESSURE; BRADYKININ; CANAVANINE; ENZYME INHIBITORS; HEMODYNAMIC PROCESSES; HYPERTENSION, PORTAL; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; POSTOPERATIVE HEMORRHAGE; RATS; RATS, SPRAGUE-DAWLEY; SPLANCHNIC CIRCULATION; VASOPRESSINS;

EID: 0034538295     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20000067     Document Type: Article

References (64)

1. Measurements of azygos venous blood flow in the evaluation of portal hypertension in patients with cirrhosis. Clinical and hemodynamic correlation in 100 patients
2. Vasopressin and nitroglycerin in the treatment of bleeding varices: The bottom line
3. Hyposensitivity to vasopressin in a hemorrhage-transfused rat model of portal hypertension
4. Lack of vasopressin action on splanchnic hemodynamics during bleeding: A study in conscious, portal hypertensive rats
5. Hyposensitivity to vasopressin in patients with hepatitis B-related cirrhosis during acute variceal hemorrhage
6. Circulatory actions of vasopressin in anesthetized rats with portal hypertension subjected to hemorrhage
7. The treatment of portal hypertension: A meta-analytic review
8. Aminoguanidine ameliorates splanchnic hyposensitivity to glypressin in a hemorrhage-transfused rat model of portal hypertension
9. Role of angiotensin II, alpha-adrenergic system and arginine vasopressin on arterial pressure in the rat
10. Mechanism of volume replacement and vascular constriction following hemorrhage
11. The role of nitric oxide in the vascular hyporesponsiveness to methoxamine in portal hypertensive rats
12. In vitro hyporeactivity to methoxamine in portal hypertensive rats: Reversal by nitric oxide inhibition
13. Modulation of the hyperdynamic circulation of cirrhotic rats by nitric oxide inhibition
14. Ω-nitro-L-arginine administration corrects peripheral vasodilation and systemic capillary hypotension, and ameliorates plasma volume expansion and sodium retention in portal hypertensive rats
15. Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide
16. Aminoguanidine inhibits both constitutive and inducible nitric oxide synthase isoforms in rat intestinal microvasculature in vivo
17. Aminoguanidine-provoked leukocyte adherence to rat mesenteric venules: Role of constitutive nitric oxide inhibition
18. Aminoguanidine selectively inhibits inducible nitric oxide synthase
19. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine
20. Inhibition of adrenergic vasoconstriction by endothelial cell shear stress
21. Mechanoreception by the endothelium: Mediators and mechanisms of pressure- and flow-induced vascular responses
22. Effects of angiotensin-converting-enzyme inhibition on bradykinin metabolism by vascular endothelial cells
23. Tyrosine phosphorylation and bradykinin-induced signaling in endothelial cells
24. Intracellular alkalinization induced by bradykinin sustains activation of the constitutive nitric oxide synthase in endothelial cells
25. Bradykinin release into portal blood during hemorrhagic shock
26. Endothelium-dependent responses and their potential relevance to the distribution of blood flow during haemorrhagic shock
27. Nitric oxide: Physiology, pathophysiology, and pharmacology
28. Hemodynamic and hormonal responses to long-term inhibition of nitric oxide synthesis in rats with portal hypertension
29. L-canavanine restores blood pressure in a rat model of endotoxic shock
30. Beneficial effects of L-canavanine, a selective inhibitor of inducible nitric oxide synthase, during rodent endotoxemia
31. Hoe 140, a new potent and long acting bradykinin antagonist: In vivo studies
32. Modulation of enhanced vascular permeability in tumors by a bradykinin antagonist, a cyclooxygenase inhibitor, and a nitric oxide scavenger
33. Measurement of the portal-systemic shunting in the rat by using γ-labeled microspheres
34. Toxicity and pharmacokinetics of the nonprotein amino acid L-canavanine in the rat
35. Cerebrovascular consequences of repeated exposure to a nitric oxide synthase inhibitor
36. G-nitro-L-arginine methyl ester to the rat on inhibition of nitric oxide-mediated responses
37. Endothelial calcium-calmodulin dependent nitric oxide synthase in the in vitro vascular hyporeactivity of portal hypertensive rats
38. Increased endothelial nitric oxide synthase activity in the hyperemic vessels of portal hypertensive rats
39. Vascular nitric oxide production during the development of two experimental models of portal hypertension
40. Evidence against a role for inducible nitric oxide synthase in the hyperdynamic circulation of portal-hypertensive rats
41. Portal hypertension activates the nitric oxide synthase genes in the esophageal mucosa of rats
42. Ω-nitro-L-arginine ameliorates portal systemic shunts in portal-hypertensive rats
43. The effect of nitric oxide synthase inhibition on portal pressure and azygos blood flow in patients with cirrhosis
44. Dose-dependent effects of a nitric oxide biosynthesis inhibitor on hyperdynamic circulation in two models of portal hypertension in conscious rats
45. The role of vasopressin in blood pressure regulation immediately following acute hemorrhage in the rat
46. Vasopressin and renin response hemorrhage in conscious, cardiac denervated dogs
47. Hemorrhagic shock and the central vasopressin and opioid peptide system of rats
48. Hemorrhage induces an increase in serum TNF which is not associated with elevated levels of endotoxin
49. Nitric oxide synthesis in endothelial cells: Evidence for a pathway inducible by TNF-α
50. Vasopressin: An essential pressor factor for blood pressure recovery following hemorrhage
51. Role of the sympathetic nervous system in hemorrhage
52. Is bradykinin (BK) a physiological vasodilator in the gut?
53. Effect of bradykinin on celiac and superior mesenteric angiography
54. Portal pressure change after injection of bradykinin and vasopressin in celiac and superior mesenteric artery
55. Superior mesenteric blood flow in man following injection of bradykinin and vasopressin into the superior mesenteric artery
56. Bioregulation of kinins: Kallikreins, kininogens, and kininases
57. A bradykinin antagonist inhibited nitric oxide generation and thromboxane biosynthesis in acute pancreatitis
58. Effects of bradykinin and icatibant in renal hemodynamics in conscious spontaneously hypertensive and normotensive rats
59. Involvement of bradykinin and nitric oxide in the early hemodynamic effects of lipopolysaccharide in rats
60. Vasopressin and renin responses to hemorrhage in conscious, cardiac denervated dogs
61. 9-bradykinin and bradykinin
62. Endothelium-derived hyperpolarizing factor; a key mediator of the vasodilator action of bradykinin
63. Prostacyclin mediates splanchnic vascular response to norepinephrine in portal hypertension
64. Modulation of splanchnic vascular sensitivity to angiotensin II