An ex vivo model of tolerance vs. rejection: Comparison of different signal transducers and activators of transcription, STAT1, STAT4, STAT5 and STAT6

Clinical Chemistry and Laboratory Medicine

Volumn 38, Issue 11, 2000, Pages 1195-1199

  Metcalfe, S ^a   Moffatt Bruce, S ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Peripheral tolerance; STATs

Indexed keywords

ALLOANTIGEN; DNA; STAT1 PROTEIN; STAT4 PROTEIN; STAT5 PROTEIN; STAT6 PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOPLASM; GRAFT REJECTION; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; IN VITRO STUDY; LYMPHOCYTE; LYMPHOCYTE ACTIVATION; MODEL; MOUSE; NONHUMAN; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; GRAFT REJECTION; MICE; MICE, INBRED BALB C; MICE, INBRED CBA; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS;

ANIMALIA; RODENTIA;

EID: 0034536053     PISSN: 14346621     EISSN: None     Source Type: Journal    
DOI: 10.1515/CCLM.2000.187     Document Type: Article

References (10)

1. Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor
2. Interleukin 12 signalling in TH1 cells involves tyrosine phosphorylation of STAT3 and STAT4
3. Activation of different STAT 5 isoforms contributes to cell-type restricted signalling in response to interferons
4. Essential role of STAT6 in IL4 signalling
5. STAT5 interaction with the TCR complex and stimulation of T cell proliferation
6. Amplification of natural regulatory immune mechanisms for transplantation tolerance
7. Stat 6 upregulation by FK506 in the presence of IL4
8. Actin cleavage by CPP-32/apopain during the development of apoptosis
9. Jaks, STATs, cytokine signal transduction, and immunoregulation: Are we there yet?
10. Transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells