STAT 6 up-regulation by FK506 in the presence of interleukin-4

Transplantation

Volumn 69, Issue 7, 2000, Pages 1521-1523

  Moffatt, Susan D ^a   Cockman, Matthew ^a   Metcalfe, Su M ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 4; STAT6 PROTEIN; TACROLIMUS;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; GRAFT REJECTION; GRAFT SURVIVAL; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; TRANSPLANTATION;

EID: 0034655389     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-200004150-00056     Document Type: Article

References (12)

1. Chen N, Gao Q, Field EH. Prevention of TH1 responses is critical for tolerance. Transplantation 1996; 61: 1076.
2. Strom TB, Roy-Chaudhury P, Manfro R, et al. The Th1/Th2 paradigm and the allograft response. Curr Opinion Immunol 1996; 8: 688.
3. O'Shea JJ. Jaks, STATs, cytokine signal transduction, and immunoregulation: are we there yet? Immunity 1997; 7: 1.
4. Liu KD, Gaffen SL, Goldsmith MA. JAK/STAT signalling by cytokine receptors. Curr Opinion Immunol 1998; 10: 271.
5. Deng W, Ohmori Y, Hamilton TA. LPS does not directly induce STAT activity in mouse macrophages. Cell Immunol 1996; 170: 20 .
6. Sigal NH, Dumont F. Cyclosporin A, FK506, and rapamycin: pharmacologic probes of lymphocyte signal transduction. Annu Rev Immunol 1992; 10: 51.
7. Takeda K, Kishimoto T, Akira S. STAT6: its role in interleukin 4-mediated biological functions. J Mol Med 1997; 75: 317.
8. Davies JD, Martin G, Phillips J, Marshall SE, Cobbold SP, Waldmann H. T cell regulation in adult transplantation tolerance. J Immunol 1996; 157: 529.
9. Galat A, Metcalfe, SM. Peptidylproline cis/trans isomerases. Prog Biophys Mol Biol 1995; 63: 67.
10. Fuchs SY, Fried VA, Ronai Z. Stress-activated kinases regulate protein stability. Oncogene 1998; 17: 1483.
11. Zheng W, Flavell RA. The transcription factor GATA3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997; 89: 587.
12. O'Keefe SJ, Tamura J, Kincaid RL, Tocci MJ, O'Neill EA. FK506 and CsA-sensitive activation of the IL2-promoter by calcineurin. Nature 1992; 357: 38.