Technique for bilateral intracranial implantation of cells in monkeys using an automated delivery system

Cell Transplantation

Volumn 9, Issue 5, 2000, Pages 595-607

  Bankiewicz, Krys S ^a   Bringas, John ^b   Pivirotto, Phillip ^a   Kutzscher, Ethan ^c   Nagy, Dea ^d   Emborg, Marina E ^e  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b PRA International USA   (Netherlands)

^c CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cell therapy; CNS; Grafting; Magnetic resonance imaging; Primates

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; AUTOMATION; AUTOTRANSPLANTATION; BRAIN REGION; CANNULA; CELL DENSITY; CELL TRANSPLANTATION; CENTRAL NERVOUS SYSTEM; CONFERENCE PAPER; CONTROLLED STUDY; DEVICE; FIBROBLAST; GENE TRANSFER; GRAFT SURVIVAL; MACACA; NEUROSURGERY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; SURGICAL TECHNIQUE; TREATMENT OUTCOME;

ANIMALIA; MACACA; MACACA MULATTA; PRIMATES;

EID: 0034534684     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1177/096368970000900505     Document Type: Conference Paper

References (28)

1. Delayed stereotactic transplantation technique in non-human primates
2. Intracerebral grafting of neuronal cell suspensions. I. Introduction and general methods of preparation
3. A computerized tomography-computer graphics approach to sttereotaxic localization
4. Animal research stereotactic instrument modified for computed tomographic guidance
5. Stereotaxic technique for transplantation of neural tissues in the brain of adult rats
6. Basic neural transplantation techniques. I. Dissociated cell suspension grafts of embryonic ventral mesencephalon in the adult rat brain
7. Stereotaxic technique for stimulation and recording in nonanesthetized monkeys: Application to the determination of connections between caudate nucleus and substantia nigra
8. Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce L-DOPA
9. Stereotactic surgery in the rhesus monkey (Macaca mulatta) utilizing intracerebral landmarks
10. Stereotaxtic neurosurgery in experimental animals. Use of intracerebral landmarks and an atlas of the cat brain
11. Intracerebral grafting of cultured autologous skin fibroblasts into the rat striatum: An assessment of graft size and ultrastructure
12. Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease
13. Treatment with fetal allografts
14. Stereotaxis and tomography: A technical note
15. Stereotaxis and nuclear magnetic resonance
16. A new fixation device for the Leksell stereotaxic system
17. A magnetic resonance imaging contrast agent differentiates between the vascular properties of fetal striatal tissue transplants and gliomas in rat brain in vivo
18. Preparation of cell suspensions for co-transplantation: Methodological considerations
19. Implantation of dispersed cells into primate brain
20. Multi-column infusion of gene therapy cells into human brain tumor: Technical report
21. Neural transplantation of human neuroteratocarcinoma (hNT) neurons into ischemic rats. A quantitative dose-response analysis of cell survival and behavioral recovery
22. Reversal of parkinsonism by fetal nerve cell transplants in primate brain
23. Somatic gene transfer to the adult primate central nervous system: In vitro and in vivo characterization of cells genetically modified to secrete nerve growth factor
24. Targeted intraparenchymal delivery of human NGF by gene transfer to the primate basal forebrain for 3 months does not accelerate beta-amyloid plaque deposition
25. Gene therapy in the adult primate brain: Intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration
26. Methodology of intracerebral microdialysis in nonhuman primates
27. An improved procedure for pressure-free insertion of tissue into the central nervous system