Determination of endogenous growth factors in human wound fluid: Temporal presence and profiles of secretion

Plastic and Reconstructive Surgery

Volumn 102, Issue 1, 1998, Pages 117-123

  Vogt, Peter M ^a   Lehnhardt, M ^b   Wagner, D ^b   Jansen, V ^b   Krieg, M ^b   Steinau, H U ^b  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CYTOKINE; EPIDERMAL GROWTH FACTOR; GROWTH FACTOR; INTERLEUKIN 1ALPHA; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR B; SODIUM CHLORIDE; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; VINYL DERIVATIVE;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; EPITHELIZATION; EXUDATE; FEMALE; HUMAN; HUMAN TISSUE; INFLAMMATION; MALE; PRIORITY JOURNAL; SECRETION; SKIN INJURY; WOUND HEALING;

ADULT; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPIDERMAL GROWTH FACTOR; EPITHELIUM; EXUDATES AND TRANSUDATES; FEMALE; FIBROBLAST GROWTH FACTOR 2; GROWTH SUBSTANCES; HUMANS; INFLAMMATION; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; INTERLEUKIN-1; MALE; MIDDLE AGED; PLATELET-DERIVED GROWTH FACTOR; PROTEINS; RECONSTRUCTIVE SURGICAL PROCEDURES; SKIN; TIME FACTORS; TRANSFORMING GROWTH FACTOR BETA; WOUND HEALING;

EID: 0031775998     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006534-199807000-00018     Document Type: Article

References (23)

1. Katz, M. H., Alvarez, A. F., Kirsner, R. S., Eaglstein, W. H., and Falanga, V. Human wound fluid from acute wounds stimulates fibroblast and endothelial cell growth. J. Am. Acad. Dermatol. 25: 1054, 1991.
2. Marikowsky, M., Breuing, K., Liu, P. Y., et al. Appearance of heparin-binding-epidermal growth factor (HB-epidermal growth factor) in wound fluid as a response to injury. Proc. Natl. Acad. Sci. U.S.A. 90: 3889, 1992.
3. Pricolo, V. E., Caldwell, M. D., Mastrofrancesco, B., and Mills, C. D. Modulatory activities of wound fluid on fibroblast proliferation and collagen synthesis. J. Surg. Res. 48: 534, 1990.
4. Brown, G. L., Nanney, L. B., Griffen, J., et al. Enhancement of wound healing by topical treatment with epidermal growth factor. N. Engl. J. Med. 321: 76, 1989.
5. Robson, M. C., Phillips, L. G., Lawrence, W. T., et al. The safety and effect of topically applied recombinant basic fibroblast growth factor on the healing of chronic pressure sores. Ann. Surg. 216: 401, 1992.
6. Robson, M. C., Phillips, L. G., Thomason, A., et al. Recombinant human platelet-derived growth factor-BB for the treatment of chronic pressure ulcers. Ann. Plast. Surg. 29: 193, 1992.
7. Robson, M. C., Phillip, L. G., Cooper, D. M., et al. Safety and effect of transforming growth factor beta 2 for treatment of venous stasis ulcers. Wound Rep. Reg. 3: 157, 1995.
8. Breuing, K., Eriksson, E., Liu, P. Y., and Miller, D. R. Healing of partial thickness porcine skin wounds in a liquid environment. J. Surg. Res. 52: 50, 1992.
9. Winter, G. D. Formation of the scab and the rate of epithelialization of superficial wounds in the skin of the young domestic pig. Nature 193: 293, 1962.
10. Hansbrough, J. F. Use of Biobrane for extensive posterior donor site wounds. J. Burn Care Rehabil. 16: 335, 1995.
11. Herndon, D. N., Barrow, R. E., Kunkel, K. R., Broemeling, L., and Rutan, R. L. Effects of recombinant human growth hormone on donor-site healing in severely burned children. Ann. Surg. 212: 424, 1990.
12. Andree, C., Swain, W. F., Page, C. P., et al. In vivo transfer and expression of a human epidermal growth factor gene accelerates wound repair. Proc. Natl. Acad. Sci. U.S.A. 91: 12188, 1994.
13. Vogt, P. M., Andree, C., Breuing, K., et al. Dry, moist, and wet skin wound repair. Ann. Plast. Surg. 34: 493, 1995.
14. Dvonch, V. M., Murphey, R. J., Matsuoka, J., and Grotendorst, G. R. Changes in growth factor levels in human wound fluid. Surgery 112: 18, 1992.
15. Pricolo, V. E., Caldwell, M. D., Mastrofrancesco, B., and Mills, C. D. Modulatory activities of wound fluid on fibroblast proliferation and collagen synthesis. J. Surg. Res. 48: 534, 1990.
16. Baxter, C. Insulin-like Growth Factor Binding Proteins. In Modern Concepts of Insulin-like Growth Factors, 1991. P. 381.
17. Batch, J. A., Mercuri, F. A., Edmondson, S. R., and Werther, G. A. Localization of messenger ribonucleic acid for insulin-like growth factor-binding proteins in human skin by in situ hybridization. J. Clin. Endocrinol. Metab. 79: 1444, 1994.
18. Antoniades, H. N., Galanopoulos, T., Neville-Golden, J., Kiritsy, C. P., and Lynch, S. E. Injury induces in vivo expression of platelet-derived growth factor and platelet-derived growth factor receptor mRNAs in skin epithelial cells and platelet-derived growth factor mRNA in connective tissue fibroblasts. Proc. Natl. Acad. Sci. U.S.A. 88: 565, 1991.
19. Antoniades, H. N., Galanopoulos, T., Neville-Golden, J., Kiritsy, C. P., and Lynch, S. E. Expression of growth factor and receptor mRNAs in skin epithelial cells following acute cutaneous injury. Am. J. Pathol. 142: 1099, 1993.
20. Brem, H., Shing, Y., Watanabe, H., et al. Temporal expression of basic fibroblast growth factor during wound healing. Surg. Forum 43: 664, 1992.
21. Andreatta-van Leyen, S., Smith, D. J., Bulgrin, J. P., Schafer, L. A., and Eckert, R. L. Delivery of growth factor to wounds using a genetically engineered biological bandage. J. Biomed. Mater. Res. 27: 1201, 1993.
22. Grayson, S., Hansbrough, J. F., Zapata-Sirvent, R. L., Dore, C. A., Morgan, J. L., and Nicolson, M. A. Quantitation of cytokine levels in skin graft donor site wound fluid. Burns 19: 401, 1993.
23. Ferguson, M. W. J. Growth Factor Profiles of Acute and Chronic Wounds. In Proceedings of the Joint Meeting of the Wound Healing Society and ETRS, Boston, May 15-19, 1996.