Cloning and characterization of pcd encoding Δ́-piperideine-6-carboxylate dehydrogenase from Flavobacterium lutescens IFO3084

Journal of Biochemistry

Volumn 128, Issue 6, 2000, Pages 975-982

  Fujii, T ^a   Narita, T ^a   Agematu, H ^a   Agata, N ^a   Isshiki, K ^a  

^a MERCIAN CORPORATION   (Japan)

Author keywords

Flavobacterium lutescens IFO3084; L aminoadipic acid (L AAA); Lat; Pcd; piperideine 6 carboxylate (P6C)

Indexed keywords

2 AMINOADIPIC ACID; BACTERIAL ENZYME; DELTA PIPERIDINE 6 CARBOXYLATE DEHYDROGENASE; LYSINE 6 AMINOTRANSFERASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GENE; ESCHERICHIA COLI; FLAVOBACTERIUM; FLAVOBACTERIUM LUTESCENS; GENE EXPRESSION; GENE SEQUENCE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; STREPTOMYCES CLAVULIGERUS;

'FLAVOBACTERIUM' LUTESCENS; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; FLAVOBACTERIUM; PROKARYOTA; STREPTOMYCES CLAVULIGERUS;

EID: 0034531812     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.jbchem.a022849     Document Type: Article

References (11)

1. Lysine catabolism in Streptomyces spp. is primarily through cadaverine: β-lactam producers also make α-aminoadipate
2. A gene encoding lysine 6-aminotransferase, which forms the β-lactam precursor α-aminoadipic acid, is located in the cluster of cephamycin biosynthetic genes in Nocardia lactamdurans
3. Localization of the lysine ε-aminotransferase (lat) and δ-(L-α-aminoadipyl)-L-cysteinyl-D-valine synthetase (pcdAB) genes from Streptomyces clavuligerus and production of lysine ε-aminotransferase activity in Escherichia coli
4. L-Lysine:α-ketoglutarate aminotransferase. I. Identification of a product, Δ-1-piperideine-6-carboxylic acid
5. Characterization of L-lysine 6-aminotransferase and its structural gene from Flavobacterium lutescens IFO3084
6. Delta-1-piperideine-6-carboxylate dehydrogenase, a new enzyme that forms α-aminoadipate in Streptomyces clavuligerus and other cephamycin C-producing actinomycetes
7. The pcd gene encoding piperideine-6-carboxylate dehydrogenase involved in biosynthesis of alpha-aminoadipic acid is located in the cephamycin cluster of Streptomyces clavuligerus
8. Amino acid analysis by reverse-phase high-performance liquid chromatography: Precolumn derivatization with phenylisothiocyanate
9. Rapid analysis of amino acids using pre-column derivatization
10. Mutational analysis of the feedback sites of lysine-sensitive aspartokinase of Escherichia coli
11. Nucleotide sequence of the pyrD gene of Escherichia coli and characterization of the flavoprotein dihydroorotate dehydrogenase