Genetic analysis of the Drosophila DNAprim gene: The function of the 60-kD primase subunit of DNA polymerase opposes the fat facets signaling pathway in the developing eye

Genetics

Volumn 156, Issue 4, 2000, Pages 1787-1795

  Chen, X ^a   Li, Q ^a   Fischer, J A ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; DNA PRIMASE;

ALLELE; ARTICLE; CELL COMMUNICATION; CELL CYCLE; DNA REPLICATION; DNA SEQUENCE; DROSOPHILA; ENZYME ACTIVITY; EYE DEVELOPMENT; GENETIC ANALYSIS; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; VISUAL DISCRIMINATION;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; CELL COMMUNICATION; CELL CYCLE; DNA PRIMASE; DROSOPHILA MELANOGASTER; ENDOPEPTIDASES; EYE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENES, INSECT; GENES, LETHAL; GENES, SUPPRESSOR; INSECT PROTEINS; LARVA; MALE; MOLECULAR SEQUENCE DATA; MORPHOGENESIS; MUTAGENESIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN SUBUNITS; SIGNAL TRANSDUCTION; UBIQUITINS;

EID: 0034530381     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (51)

1. The 50 kD primase subunit of Drosophila melanogaster DNA polymerase alpha molecular characterization of the gene and functional analysis of the overexpressed protein
2. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
3. The function of the Drosophila Fat facets deubiquitinating enzyme in limiting photoreceptor cell number is intimately associated with endocytosis
4. Seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye
5. UbcD1, a Drosophila deubiquitinating enzyme required for proper telomere behavior
6. In vivo structure/function analysis of the Drosophila fat facets deubiquitinating enzyme gene
7. Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis
8. A DNA primase activity associated with DNA polymerase alpha from Drosophila melanogaster embryos
9. DNA polymerase-primase from embryos of Drosophila melanogaster the DNA polymerase subunit
10. J Biol Chem
11. Cloning of the gene for the 73 kD subunit of the DNA polymerase alpha primase of Drosophila melanogaster
12. Expression, purification, and characterization of the two human primase subunits and truncated complexes from Escherichia coli
13. Mutations Hsp83 and cdc37 impair signaling by the Sevenless receptor tyrosine kinase
14. Atonal, rough and the resolution of proneural clusters in the developing Drosophila retina
15. Mutagenesis screens for interacting genes reveal three roles for fat facets during Drosophila eye development
16. The fat facets gene is required for Drosophila eye and embryo development
17. The Flybase database of the Drosophila genome projects and community literature
18. Affinity labeling of the active center and ribonucleoside triphosphate binding site of yeast DNA primase
19. The deubiquitinating enzymes
20. Structure and expression during development of Drosophila melanogaster gene for DNA polymerase alpha
21. Undifferentiated cells in the developing Drosophila eye influence facet assembly and require the Fat facets deubiquitinating enzyme
22. Control of cell fate by a deubiquitinating enzyme encoded by the fat facets gene
23. Cloning and characterization of the gene for the large subunit of the DNA primase from Drosophila melanogaster
24. Mutations affecting the pattern of the larval cuticle in Drosophila melanogaster
25. DNA polymerase α
26. Method of feeding ethyl methanesulfonate (EMS) to Drosophila males
27. Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack
28. Genetic characterization of cytological region 77A-D harboring the Presenilin gene of Drosophila melanogaster
29. Molecular characterization of the gene for the 180 kDa subunit of the DNA polymerase-primase of Drosophila melanogaster
30. DNA polymerase alpha-primase from calf thymus determination of the polypeptide responsible for primase activity
31. The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins
32. A genetic screen to identify componenets of the sina signaling pathway in Drosophila eye development
33. DNA polymerase I gene of Saccharomyces cerevisiae nucleotide sequence, mapping of a temperature-sensitive mutation, and protein homology with other DNA polymerases
34. A stable source of P element transposase in Drosophila melanogaster
35. Comparative genomics of eukaryotes
36. The Drosophila Exp78c gene is not vital but has a role in regulating chromosome puffs
37. The isolated 48,000-dalton subunit of yeast DNA primase is sufficient for RNA primer synthesis
38. Identification of an essential gene, l(3)73Ai, with a dominant temperature-sensitive lethal allele, encoding a Drosophila proteasome subunit
39. P-element mediated transformation
40. The Berkeley Drosophila genome project gene disruption project single P element insertions mutating 25% of vital Drosophila genes
41. Cell fate in the Drosophila ommatidium
42. Neuronal differentiation in the Drosophila ommatidium
43. Drosophila UbcD1 encodes a highly conserved ubiquitin-conjugating enzyme involved in selective protein degradation
44. The deubiquitinating enzymes
45. The beginning of pattern formation in the Drosophila compound eye the morphogenetic furrow and the second mitotic wave
46. Pattern formation in the Drosophila retina
47. Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure in similar to both prokaryotic and eukaryotic replicative DNA polymerases
48. Genetic analysis of the role of the Drosophila fat facets genem the ubiquitin pathway
49. Proteasomal regulation of nuclear receptor corepressor-mediated repression