Efficient Cre/loxP site-specific recombination in a HepG2 human liver cell line

Cell Transplantation

Volumn 9, Issue 5, 2000, Pages 737-742

  Kobayashi, Naoya ^a   Noguchi, Hirofumi ^a   Westerman, Karen A ^b   Matsumura, Toshihisa ^a   Watanabe, Takamasa ^a   Totsugawa, Toshinori ^a   Fujiwara, Toshiyoshi ^a   Leboulch, Philippe ^b   Tanaka, Noriaki ^a  

^a OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Cre loxP site specific recombination; HepG2 cells; Reversible immortalization

Indexed keywords

CRE RECOMBINASE; GENE PRODUCT; PROTEIN LOXP; RECOMBINASE; UNCLASSIFIED DRUG; VIRUS T ANTIGEN; VIRUS VECTOR;

CELL IMMORTALIZATION; CELL LINE; CELL POPULATION; CELL TRANSPLANTATION; CONFERENCE PAPER; CONTROLLED STUDY; GENE TRANSFER; GENETIC RECOMBINATION; HUMAN; HUMAN CELL; LIVER CELL; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; RETROVIRUS; SIMIAN VIRUS; VIRUS RECOMBINANT;

ADENOVIRIDAE; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40; UNIDENTIFIED RETROVIRUS;

EID: 0034529735     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.1177/096368970000900525     Document Type: Conference Paper

References (13)

1. Hepatocyte transplantation: Prognosis for a clinical future
2. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through cre-loxP-mediated gene targeting
3. Deletion of a DNA polymerase b gene segment in T cells using cell type-specific gene targeting
4. Hepatocyte transplantation: Back to the future
5. A short amino acid sequence able to specify nuclear location
6. Efficient gene activation system on mammalian cell chromosomes using recombinant adenovirus producing Cre recombinase
7. Inducible gene targeting in mice
8. Targeted oncogene activation by site-specific recombination in transgenic mice
9. Curability of tumors bearing herpes thymidine kinase genes transferred by retroviral vectors
10. Efficient selection for high-expression transfectants with a novel eukaryotic vector
11. Bacteriophage P1 site-specific recombination I. Recombination between loxP sites
12. Hepatocyte transplantation as a bridge to orthotopic liver transplantation in terminal liver failure
13. Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination