Stronger association with HLA-Cw6 than with corneodesmosin (S-gene) polymorphisms in Swedish psoriasis patients

Archives of Dermatological Research

Volumn 292, Issue 11, 2000, Pages 525-530

  Enerback C ^a   Nilsson, S ^b   Enlund, F ^a   Inerot, A ^a   Samuelsson, L ^a   Wahlstrom J ^a   Swanbeck, G ^a   Martinsson, T ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

Author keywords

Cw6; HLA antigens; Linkage disequilibrium; Psoriasis

Indexed keywords

DESMOSINE; HLA C ANTIGEN; HLA CW6 ANTIGEN; LEUKOCYTE ANTIGEN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ALLELE; ANTIGEN BINDING; ARTICLE; BINDING SITE; BLOOD SAMPLING; CHILD; CLINICAL ARTICLE; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; HAPLOTYPE; HUMAN; MALE; MULTIGENE FAMILY; ONSET AGE; PRIORITY JOURNAL; PSORIASIS; SWEDEN;

ALLELES; DNA; FAMILY HEALTH; FEMALE; GENOTYPE; GLYCOPROTEINS; HAPLOTYPES; HLA-C ANTIGENS; HUMANS; LOD SCORE; MALE; MICROSATELLITE REPEATS; PEDIGREE; POLYMORPHISM, GENETIC; PSORIASIS; SEQUENCE ANALYSIS, DNA; SWEDEN;

EID: 0034528978     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004030000175     Document Type: Article

References (26)

1. The genetics of psoriasis
2. Psoriasis and HLA-Cw6
3. Study of HLA class I, class II and complement genes (C2 C4A, C4B and BF) in Japanese psoriatics and analysis of a newly-found high-risk haplo-type by pulsed field gel electrophoresis
4. HLA-CW *0602 is a susceptibility factor in type I psoriasis, and evidence Ala-73 is increased in male type I psoriatics
5. Psoriasis of early and late onset: Characterization of two types of psoriasis vulgaris
6. Evidence that HLA-Cw6 determines early onset of psoriasis, obtained using sequence-specific primers (PCR-SSP)
7. Linkage disequilibrium analysis of familial psoriasis: Identification of multiple disease-associated MHC haplotypes
8. Significantly earlier age at onset for the HLA-Cw6-positive than for the Cw6-negative psoriatic sibling
9. Transmission test for linkage disequilibrium: The insulin gene region and insulin-dependent diabetes mellitus (IDDM)
10. A population genetic study of psoriasis
11. Age at onset and different types of psoriasis
12. Analysis of three suggested psoriasis susceptibility loci in a large Swedish set of families: Confirmation of linkage to chromosome 6p (HLA region), and to 17q, but not to 4q
13. Psoriasis susceptibility locus in chromosome region 3q21 identified in patients from southwest Sweden
14. Phototyping: Comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 and DQB 1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP)
15. Microsatellites in the HLA region: On overview
16. Comprehensive method for the typing of HLA-A, B, and C alleles by direct sequencing of PCR products obtained from genomic DNA
17. Parametric and nonparametric linkage analysis: A unified multipoint approach
18. Genetics of psoriasis: Paternal inheritance and a locus on chromosome 6p
19. HLA risk haplotype Cw6,DR7,DQA1 *0201 and HLA-Cw6 with reference to the clinical picture of psoriasis vulgaris
20. Sequence-based typing provides a new look at HLA-C diversity
21. The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens
22. A non-HLA gene within the MHC in psoriasis
23. Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis
24. Corneodesmosin gene polymorphism demonstrates strong linkage disequilibrium with HLA and association with psoriasis vulgaris
25. A genome-wide search for genes predisposing to familial psoriasis; Results from a stratification approach
26. S gene (comeodesmosin) diversity and its relationship to psoriasis; High content of cSNPs in the HLA-linked S gene