Interleukin (IL)-6 release and fever induced by a pre-formed pyrogenic factor (PFPF) derived from LPS-stimulated macrophages

European Cytokine Network

Volumn 11, Issue 4, 2000, Pages 589-596

  Zampronio, A R ^a   Hoadley, M E ^a   Luheshi, G ^a   Rothwell, N J ^a   Petto de Souza, G E ^a   Hopkins, S J ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Air pouch; Cytokines; Fever; Interieukin 6; Macrophages; Pyrogenic factor

Indexed keywords

ANTIBODY; INDOMETACIN; INTERLEUKIN 1; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PYROGEN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; FEVER; ISOELECTRIC FOCUSING; MACROPHAGE; MALE; NONHUMAN; RAT;

ANIMALS; CELLS, CULTURED; CYTOKINES; FEVER; INDOMETHACIN; INTERLEUKIN-6; ISOELECTRIC FOCUSING; LIPOPOLYSACCHARIDES; MACROPHAGE ACTIVATION; MACROPHAGES, PERITONEAL; MALE; PYROGENS; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR;

ANIMALIA;

EID: 0034525229     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Febrile response to tissue inflammation involves both peripheral and brain IL-1 and TNF-α in the rat
2. Fever: Role of pyrogens and cryogens
3. Interleukin-8 induces fever by a prostaglandin-independent mechanism
4. The inflammatory response in interleukin-1β-deficient mice: Comparison with cytokine related knock-out mice
5. Intefleukin (IL)-6 gene expression in central nervous system is necessary for fever response to lipopolysaccharide or IL-1β: A study on IL-6 deficient mice
6. Exacerbated febrile responses to LPS, but not turpentine, in TNF double receptor-knockout mice
7. What roles does the organum vasculosum laminae terminalis play in fever in rabbits?
8. Blood to brain transport of interleukin links the immune and central nervous systems
9. Penetration of interleukin-6 across the murine blood-brain barrier
10. Differential permeability of the BBB in acute EAE: Enhanced transport of TNF-α
11. Blockade of interleukin-1 induced hyperthermia by subdiaphragmatic vagotomy: Evidence for vagal mediation of immune-brain communication
12. Fever suppression by subdiaphragmatic vagotomy in guinea pigs depends on the route of pyrogen administration
13. Fever: How may circulating pyrogens signal the brain?
14. A pre-formed pyrogenic factor released by lipopolysaccharide-stimulated macrophages
15. Involvement of CHR in fever induced by a distinct pre-formed pyrogenic factor (PFPF)
16. Tumor necrosis factor (cachetin) is an endogenous pyrogen and induces production of interleukin-1
17. Interleukin-1 induces interleukin-1. I. Induction of interleukin-1 in rabbits in vivo and in human mononuclear cells in vitro
18. Interleukin-6 is involved in interleukin-1-induced activities
19. Interleukin-6: The major regulator of acute-phase protein synthesis in man and rat
20. Simple, sensitive and specific bioassay of interleukin-1
21. Relationships between local inflammation, interleukin-6 concentration and the acute phase protein response in arthritis patients
22. An improved colorimetric assay for interleukin-2
23. Local cytokine induction by LPS in the rat air pouch and its relationship to the febrile response
24. Mechanisms of pyrogenic actions of cytokines
25. A study of the pyrogenic actions of interleukin-1α and interleukin-1β: Interaction with a steroidal and non-steroidal antiinflammatory agent
26. Recombinant human tumor necrosis factor causes long-lasting and prostaglandin-mediated fever, with little tolerance, in rabbits
27. Characteristics of TNF-α- and TNF-β- induced fever in rabbit
28. Role of interleukin-6 in fever in the rat
29. Mechanisms of fever induced by recombinant human interferon
30. Fever produced by interleukin-11 (IL-11) injected into the anterior hypothalamic pre-optic area of the rat is antagonized by indomethacin
31. Roles of interleukin-1β and tumor necrosis factor in lipopolysaccharide fever in rats
32. Tumor necrosis factor-alpha and fever after peripheral inflammation in the rat