Differential expression of thyroid transcription factor 1 in small cell lung carcinoma and Merkel cell tumor

Human Pathology

Volumn 31, Issue 1, 2000, Pages 58-62

  Byrd Gloster, Angela L ^a,b,c   Khoor, Andras ^a,b,c   Glass, Lewis F ^a,b,c   Messina, Jane L ^a,b,c   Whitsett, Jeffrey A ^a,b,c   Livingston, Sandra K ^a,b,c   Cagle, Philip T ^a,b,c  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

CK20; Immunohistochemistry; Merkel cell tumor; Small cell lung carcinoma; TTF 1

Indexed keywords

BIOTIN; CYTOKERATIN 20; MONOCLONAL ANTIBODY; PARAFFIN; STREPTAVIDIN; THYROID TRANSCRIPTION FACTOR 1; TUMOR MARKER;

ARTICLE; BRONCHUS MUCOSA; DATA ANALYSIS; DIAGNOSTIC ACCURACY; GENE EXPRESSION; GENETIC TRANSCRIPTION; HISTOPATHOLOGY; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY; MERKEL CELL TUMOR; STATISTICAL ANALYSIS; THYROGLOBULIN BLOOD LEVEL; TUMOR DIAGNOSIS;

EID: 0033958853     PISSN: 00468177     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0046-8177(00)80199-9     Document Type: Article

References (20)

1. Bonomi P Review of selected randomized trials in small cell lung cancer Semin Oncol 25 1998 70 78
2. Queirolo P Gipponi M Peressini A Merkel cell carcinoma of the skin: Treatment of primary, recurrent, and metastatic disease: Review of clinical cases Anticancer Res 17 1997 673 677
3. Lazzaro D Price M de Felice M The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain Development 113 1991 1093 1104
4. Stahlman MT Gray ME Whitsett JA Expression of thyroid transcription factor-1 (TTF-1) in fetal and neonatal human lung J Histochem Cytochem 44 1996 673 678
5. Bruno MD Bohinski RJ Huelsman KM Lung cell-specific expression of the murine surfactant protein A (SP-A) gene is mediated by interactions between the SP-A promoter and thyroid transcription factor-1 J Biol Chem 270 1995 6531 6536
6. Bohinski RJ Di Lauro R Whitsett JA The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis Mol Cell Biol 14 1994 5671 5681
7. Zhang L Whitsett JA Stripp BR Regulation of Clara cell secretory protein gene transcription by thyroid transcription factor-1 Biochim Biophys Acta 1350 1997 359 367
8. Bejarano PA Baughman RP Biddinger PW Surfactant proteins and thyroid transcription factor-1 in pulmonary and breast carcinomas Mod Pathol 9 1996 445 452
9. Khoor A Whitsett JA Stahlman MT Utility of surfactant protein B precursor and thyroid transcription factor 1 in differentiating adenocarcinoma of the lung from malignant mesothelioma Hum Pathol 30 1999 695 700
10. Di Loreto C Di Lauro V Puglisi F Immunocytochemical expression of tissue specific transcription factor-1 in lung carcinoma J Clin Pathol 50 1997 30 32
11. Folpe AL Gown AM Lamps LW Thyroid transcription factor-1: Immunohistochemical evaluation in pulmonary neuroendocrine tumors Mod Pathol 12 1999 5 8
12. Holzinger A Dingle S Bejarano PA Monoclonal antibody to thyroid transcription factor-1: Production, characterization, and usefulness in tumor diagnosis Hybridoma 15 1996 49 53
13. Elston RC Johnson WD Essentials of Biostatistics 1987 FA Davis Philadelphia, PA
14. Khoor A Gray ME Hull WM Developmental expression of SP-A and SP-A mRNA in the proximal and distal respiratory epithelium in the human fetus and newborn J Histochem Cytochem 41 1993 1311 1319
15. Khoor A Stahlman MT Gray ME Temporal-spatial distribution of SP-B and SP-C proteins and mRNAs in developing respiratory epithelium of human lung J Histochem Cytochem 42 1994 1187 1199
16. Khoor A Gray ME Singh G Ontogeny of Clara cell-specific protein and its mRNA: Their association with neuroepithelial bodies in human fetal lung and in bronchopulmonary dysplasia J Histochem Cytochem 44 1996 1429 1438
17. Fabbro D Di Loreto C Stamerra O TTF-1 gene expression in human lung tumours Eur J Cancer 32A 1996 512 517
18. Bonikos DS Archibald R Bensch KG On the origin of the so-called tumorlets of the lung Hum Pathol 7 1976 461 469
19. Wikenheiser KA Whitsett JA Tumor progression and cellular differentiation of pulmonary adenocarcinomas in SV40 large T antigen transgenic mice Am J Respir Cell Mol Biol 16 1997 713 723
20. Chan JK Suster S Wenig BM Cytokeratin 20 immunoreactivity distinguishes Merkel cell (primary cutaneous neuroendocrine) carcinomas and salivary gland small cell carcinomas from small cell carcinomas of various sites Am J Surg Pathol 21 1997 226 234