Ultraviolet radiation induces both full activation of Ret kinase and malignant melanocytic tumor promotion in RFP-RET-transgenic mice [2]

Journal of Investigative Dermatology

Volumn 115, Issue 6, 2000, Pages 1157-1158

  Kato, M ^a   Liu, W ^a   Akhand, A A ^a   Hossain, K ^a   Takeda, K ^a   Takahashi, M ^a   Nakashima, I ^a  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; PROTEIN C JUN;

ANIMAL EXPERIMENT; ANIMAL MODEL; CARCINOGENESIS; CONTROLLED STUDY; ENZYME ACTIVATION; LETTER; MALIGNANT TRANSFORMATION; MELANOMA; MOUSE; NONHUMAN; ONCOGENE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSGENIC MOUSE; ULTRAVIOLET RADIATION;

EID: 0034518239     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2000.0202a-2.x     Document Type: Letter

References (7)

1. Aberrant melanogenesis and melanocytic tumor development in transgenic mice that carry a metallothionein/ret fusion gene
2. Transgenic mouse model for skin malignant melanoma
3. Linkage between melanocytic tumor development and early burst of Ret protein expression for tolerance induction in metallothionein-I/ret transgenic mouse lines
4. Ultraviolet light induces redox reaction-mediated dimerization and superactivation of oncogenic Ret tyrosine kinases
5. Speculations on the role of ultraviolet radiation in the development of malignant melanoma
6. Activation of a novel human transforming gene, ret, by DNA rearrangement
7. Sunburn and p53 in the onset of skin cancer