Moderate hypothermia improves imbalances of thromboxane A2 and prostaglandin I2 production after traumatic brain injury in humans

Critical Care Medicine

Volumn 28, Issue 12, 2000, Pages 3902-3906

  Aibiki, Mayuki ^a   Maekawa, Souichi ^b   Yokono, Satoshi ^a  

^a KAGAWA UNIVERSITY HOSPITAL   (Japan)

^b EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Arterial jugular bulb difference; Moderate hypothermia; Normothermia; Prostaglandins; Traumatic brain injury

Indexed keywords

PROSTACYCLIN; THROMBOXANE A2;

ADOLESCENT; ADULT; AGED; ARACHIDONIC ACID METABOLISM; ARTERIAL BLOOD; ARTICLE; BRAIN INJURY; BRAIN PROTECTION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; COOLING; FEMALE; HUMAN; INDUCED HYPOTHERMIA; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; VENOUS BLOOD;

EID: 0034517886     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200012000-00029     Document Type: Article

References (29)

1. Responses of human baboon arteries to prostaglandin endoperoxides and biologically generated and synthetic prostacyclin: Their relevance to cerebral arterial spasm in man
2. Prostanoids: Intrinsic modulation of cerebral circulation
3. Alteration of thromboxane and prostacyclin levels in experimental spinal cord injury
4. Eicosanoids in human ventricular cerebrospinal fluid following severe brain injury
5. Effect of moderate hypothermia on systemic and internal jugular plasma IL-6 levels after traumatic brain injury in humans
6. Intrathecal and serum interleukin-6 and the acute-phase response in patients with severe traumatic brain injuries
7. Treatment of traumatic brain injury with moderate hypothermia
8. Hypothermia attenuates the normal increase in interleukin 1β RNA and nerve growth factor following traumatic brain injury in the rat
9. Moderate hypothermia reduces postischemic edema development and leukotriene production
10. Mild hypothermia suppresses thromboxane B2 production in brain-injured patients
11. Endotoxin activation of eicosanoid production by macrophages
12. Moderate hypothermia in patients with severe head injury: Cerebral and extracerebral effects
13. Differences in serum electrolyte changes depending on sedatives, thiamylal or midazolam, during mild hypothermia therapy
14. Disability after severe head injury: Observation on the use of the Glasgow Outcome Scale
15. Craniocerebral trauma: Protection and retrieval of the neuronal population after injury
16. Focal ischemia due to traumatic contusion documented by stable xenon CT and ultrastructural studies
17. Mild intraischemic hypothermia reduces postischemic hyperperfusion, delayed postischemic hypoperfusion, blood-brain barrier disruption, brain edema, and neuronal damage volume after temporary focal cerebral ischemia in rats
18. Eicosanoid synthesis and release from primary cultures of rat central nervous system astrocytes and meningeal cells
19. Experimental traumatic brain injury elevates brain prostaglandin E2 and thromboxane B2 levels in rats
20. Eicosanoid production by rat cerebral endothelial cells: Stimulation by lipopolysaccharide, interleukin-1 and interleukin-6
21. Interleukin-1 enhances the ATP-evoked release of arachidonic acid from mouse astrocytes
22. The influence of cytokines on the integrity of the blood-brain barrier in vitro
23. Identification of functional PGH2/TXA2 receptors on human endothelial cells
24. Mild pre- and posttraumatic hypothermia attenuates blood-brain barrier damage following controlled cortical impact injury in the rat
25. Prostaglandin profiles in tissue and blood vessels from human brain
26. Effect of intraventricular haemorrhage and rebleeding following subarachnoid haemorrhage on CSF eicosanoids
27. Ibuprofen improves cerebral blood flow after global cerebral ischemia in dogs
28. Development of cyclooxygenase and lipoxgenase metabolites of arachidonic acid after transient cerebral ischemia
29. Moderate hypothermia in the treatment of patients with severe middle cerebral artery infarction