'Mommy, why can't I have a hamburger like the other kids?'

Gene Therapy

Volumn 7, Issue 23, 2000, Pages 1969-1970

  Harding, C O ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; LIVER ENZYME; PHENYLALANINE; PHENYLALANINE 4 MONOOXYGENASE; PROTEIN; SAPROPTERIN; TYROSINE; VIRUS VECTOR;

AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; CELL ACTIVITY; CONTROLLED STUDY; DIET THERAPY; EDITORIAL; ENZYME ACTIVITY; GENE EXPRESSION; GENE THERAPY; GENETIC ENGINEERING; HUMAN; HUMAN CELL; HYDROXYLATION; KERATINOCYTE; METABOLIC CLEARANCE RATE; PHENYLKETONURIA; PRIORITY JOURNAL; PROTEIN RESTRICTION; RETROVIRUS; SKIN GRAFT;

ADOLESCENT; ADULT; BIOPTERIN; DIET, PROTEIN-RESTRICTED; FEMALE; GENE THERAPY; HUMANS; KERATINOCYTES; METABOLIC CLEARANCE RATE; PHENYLALANINE; PHENYLALANINE HYDROXYLASE; PHENYLKETONURIAS; PREGNANCY; SKIN TRANSPLANTATION;

EID: 0034515323     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301363     Document Type: Editorial

References (2)

1. Development of a skin based metabolic sink for phenylalanine by over-expression of phenylalanine hydroxylase and GTP cyclohydrolase in primary human keratinocytes
2. Reconstitution of a metabolic pathway with triple-cistronic IRES-containing retroviral vectors for correction of tetrahydrobiopterin deficiency