How does TAP pump peptides? Insights from DNA repair and traffic ATPases

Immunology Today

Volumn 21, Issue 12, 2000, Pages 598-600

  Reits, Eric A J ^a   Griekspoor, Alexander C ^a   Neefjes, Jacques ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DNA REPAIR; ENDOPLASMIC RETICULUM; ENZYME SPECIFICITY; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS INHIBITION; REVIEW;

EID: 0034502493     PISSN: 01675699     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5699(00)01720-5     Document Type: Short Survey

References (25)

1. U. Schubert Rapid degradation of a large fraction of newly synthesized proteins by proteasomes Nature 404 2000 770 774
2. E.A. Reits The major substrates for TAP in vivo are derived from newly synthesized proteins Nature 404 2000 774 778
3. A. Hill Herpes simplex virus turns off the TAP to evade host immunity Nature 375 1995 411 415
4. H. Hengel A viral ER-resident glycoprotein inactivates the MHC-encoded peptide transporter Immunity 6 1997 623 632
5. B. Seliger Expression and function of the peptide transporters in escape variants of human renal cell carcinomas Exp. Hematol. 25 1997 608 614
6. J.C. Vos Membrane topology and dimerization of the two subunits of the transporter associated with antigen processing reveal a three-domain structure J. Immunol. 163 1999 6679 6685
7. J.C. Vos Head–head/tail–tail relative orientation of the pore-forming domains of the heterodimeric ABC transporter TAP Curr. Biol. 10 2000 1 7
8. M.F. Rosenberg Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis J. Biol. Chem. 272 1997 10685 10694
9. M. Gromme The rational design of TAP inhibitors using peptide substrate modifications and peptidomimetics Eur. J. Immunol. 27 1997 898 904
10. M. Nijenhuis G.J. Hammerling Multiple regions of the transporter associated with antigen processing (TAP) contribute to its peptide binding site J. Immunol. 157 1996 5467 5477
11. M.J. Androlewicz P. Cresswell Human transporters associated with antigen processing possess a promiscuous peptide-binding site Immunity 1 1994 7 14
12. P.M. van Endert A sequential model for peptide binding and transport by the transporters associated with antigen processing Immunity 1 1994 491 500
13. E.V. Deverson Functional analysis by site-directed mutagenesis of the complex polymorphism in rat transporter associated with antigen processing J. Immunol. 160 1998 2767 2779
14. F. Momburg Selectivity of MHC-encoded peptide transporters from human, mouse and rat Nature 367 1994 648 651
15. F. Momburg Residues in TAP2 peptide transporters controlling substrate specificity J. Immunol. 156 1996 1756 1763
16. L.W. Hung Crystal structure of the ATP-binding subunit of an ABC transporter Nature 396 1998 703 707
17. K.P. Hopfner Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC–ATPase superfamily Cell 101 2000 789 800
18. P.E. Lapinski Pairing of the nucleotide binding domains of the transporter associated with antigen processing J. Biol. Chem. 275 2000 6831 6840
19. A.E. Senior The catalytic cycle of P-glycoprotein FEBS Lett. 377 1995 285 289
20. K. Szabo Nucleotide occlusion in the human cystic fibrosis transmembrane conductance regulator. Different patterns in the two nucleotide binding domains J. Biol. Chem. 274 1999 12209 12212
21. Y. Hou Allosteric interactions between the two non-equivalent nucleotide binding domains of multidrug resistance protein MRP1 J. Biol. Chem. 275 2000 20280 20287
22. L. Neumann R. Tampe Kinetic analysis of peptide binding to the TAP transport complex: evidence for structural rearrangements induced by substrate binding J. Mol. Biol. 294 1999 1203 1213
23. M.R. Knittler Nucleotide binding by TAP mediates association with peptide and release of assembled MHC class I molecules Curr. Biol. 9 1999 999 1008
24. G. Obmolova Crystal structure of mismatch repair protein MutS and its complex with a substrate DNA Nature 407 2000 703 710
25. M.H. Lamers The crystal structure of mismatch repair protein MutS binding to a G.T mismatch Nature 407 2000 711 717