Mass spectrometric and NMR characterization of metabolites of roxifiban, a potent and selective antagonist of the platelet glycoprotein IIb/IIIa receptor

Xenobiotica

Volumn 30, Issue 11, 2000, Pages 1091-1110

  Mutlib, A E ^a   Diamond, S ^a   Shockcor, J ^a   Way, R ^a   Nemeth, G ^a   Gan, L ^a   Christ, D D ^a  

^a DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOGEN RECEPTOR; ROXIFIBAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOG; DRUG ABSORPTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG HYDROLYSIS; DRUG METABOLISM; DRUG STRUCTURE; HYDROXYLATION; INTESTINE FLORA; LIVER SLICE; MALE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STEREOCHEMISTRY;

AMIDINES; AMINO ACIDS; ANIMALS; CARDIOVASCULAR AGENTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOGS; FECES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; ISOXAZOLES; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICE; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RATS; THROMBOSIS;

EID: 0034494906     PISSN: 00498254     EISSN: None     Source Type: Journal    
DOI: 10.1080/00498250010006591     Document Type: Article

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