Steroids in leprosy type 1 (reversal) reactions: Mechanisms of action and effectiveness

Leprosy Review

Volumn 71, Issue SUPPL., 2000, Pages

  Lockwood, D N J ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOCORTICOID; NONSTEROID ANTIINFLAMMATORY AGENT; PREDNISOLONE;

ANTIINFLAMMATORY ACTIVITY; CLINICAL ARTICLE; CONFERENCE PAPER; CORTICOSTEROID THERAPY; DRUG MECHANISM; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; LEPROSY; SKIN BIOPSY;

EID: 0034494461     PISSN: 03057518     EISSN: None     Source Type: Journal    
DOI: 10.5935/0305-7518.20000080     Document Type: Conference Paper

References (16)

1. The clinical features and outcome of reversal (type 1) reactions in Hyderabad, India
2. The treatment of acute nerve function impairment in leprosy: Results from a prospective cohort study in Bangladesh
3. The pattern of neuritis in the AMFES patients: Definitions, incidence, risk factors and outcome
4. A new hypothesis of modular glucocorticoid actions. Glucocorticoid treatment of rheumatic diseases revisited
5. Anti-inflammatory actions of glucocorticoids: Molecular mechanisms
6. Anti-inflammatory actions of steroids: Molecular mechanisms
7. Dexamethasone and pentoxyfylline inhibit endotoxin-induced cachectin/tumour necrosis factor synthesis at separate points in the signaling pathway
8. Negative transcriptional regulation of human interleukin 2 (IL-2) gene by glucocorticoids through interference with nuclear transcription factors AP-1 and NF-AT
9. Corticosteroids enhance the capacity of macrophages to induce Th2 cytokine synthesis in CD4+ lymphocytes by inhibiting IL-12 production
10. Dexamethasone-mediated inhibition of human T cell growth factor and γ-interferon messenger RNA
11. Mechanisms of suppression of inducible nitric-oxide synthase (iNOS) expression in interferon (IFN)-gamma-stimulated RAW 264·7 cells by dexamethasone. Evidence for glucocorticoid-induced degradation of iNOS protein by calpain as a key step in post-transcriptional regulation
12. Immunohistochemical analysis of cellular infiltrate, IFNγ, IL-12 and iNOS expression in leprosy type 1 (reversal) reactions before and during prednisolone treatment
13. Tumour necrosis factor-α synthesis is associated with the skin and peripheral nerve pathology of leprosy reversal reactions
14. Therapeutic implications of non-genomic glucocorticoid activity
15. Aggressive strategies for treating aggressive rheumatoid arthritis: Has the case been proven?