High-throughput tissue microarray analysis of cyclin E gene amplification and overexpression in urinary bladder cancer

American Journal of Pathology

Volumn 157, Issue 3, 2000, Pages 787-794

  Richter, Jan ^a   Wagner, Urs ^a   Kononen, Juha ^b   Fijan, André ^a   Bruderer, James ^a   Schmid, Ulrico ^c   Ackermann, Daniel ^c   Maurer, Robert ^d   Alund, Göran ^d   Knönagel, Hartmut ^e   Rist, Marcus ^f   Wilber, Kim ^g   Anabitarte, Manuel ^h   Hering, Franz ^h   Hardmeier, Thomas ⁱ   Schönenberger, Andreas ⁱ   Flury, Renata ^j   Jäger, Peter ^j   Fehr, Jean Luc ^k   Schraml, Peter ^a   Moch, Holger ^a   Mihatsch, Michael J ^a   Gasser, Thomas ^a   Kallioniemi, Olli P ^b   Sauter, Guido ^a   more..

^a UNIVERSITY OF BASEL   (Switzerland)

^b NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^c CANTONAL HOSPITAL ST GALLEN   (Switzerland)

^d TRIEMLI HOSPITAL   (Switzerland)

^e Limmattal Hospital   (Switzerland)

^f Clara Hospital   (Switzerland)

^g ABBOTT LABORATORIES   (United States)

^h Cantonal Hospital Baden   (Switzerland)

ⁱ Kantonsspital Muensterlingen   (Switzerland)

^j CANTONAL HOSPITAL WINTERTHUR   (Switzerland)

^k Cantonal Hospital Schaffhausen ^*  (Switzerland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN E;

ARTICLE; BLADDER CANCER; CANCER SURVIVAL; CHROMOSOME 19; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; ENZYME SUBUNIT; FLUORESCENCE IN SITU HYBRIDIZATION; FOLLOW UP; GENE AMPLIFICATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0034493879     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64592-0     Document Type: Article

References (30)

1. Detection of chromosomal imbalances in transitional cell carcinoma of the bladder by comparative genomic hybridization
2. Identification of novel DNA amplifications and deletions in primary bladder cancer by comparative genomic hybridization
3. Marked genetic differences between pTa and pT1 papillary bladder cancer detected by comparative genomic hybridization
4. Patterns of chromosomal imbalances in advanced urinary bladder cancer detected by comparative genomic hybridization
5. Chromosomal aberrations associated with invasion in papillary superficial bladder cancer
6. Genetic alterations in primary bladder cancers and their metastases
7. Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene
8. Genomic organization, chromosomal localization, and independent expression of human cyclin D genes
9. Nucleotide sequence of cloned cDNA of human c-myc oncogene
10. Mapping of the human gene for epidermal growth factor receptor (EGFR) on the p13 leads to q22 region of chromosome 7
11. Amplification of a gene encoding a p53-associated protein in human sarcomas
12. DNA copy number amplifications in human neoplasms: Review of comparative genomic hybridization studies
13. Chromosomal imbalances are associated with a high risk of progression in early invasive (pT1) urinary bladder cancer
14. Chromosomal imbalances in small cell carcinomas of the urinary bladder
15. Chromosomal imbalances in non-invasive papillary neoplasms (pTa)
16. Human cyclin E, a nuclear protein essential for the G1-to-S phase transition
17. Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family
18. Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system
19. Expression and amplification of cyclin genes in human breast cancer
20. Analysis of cyclin E and CDK2 in ovarian cancer: Gene amplification and RNA overexpression
21. Tissue microarrays for high-throughput molecular profiling of hundreds of specimens
22. Nonparametric estimation from incomplete observations
23. Survey of gene amplifications during prostate cancer progression by high-throughput fluorescence in situ hybridization on tissue microarrays
24. AKT2, a putative oncogene encoding a member of a subfamily of protein-ser ne/threonine kinases, is amplified in human ovarian carcinomas
25. Structure and mapping of the fosB gene. FosB downregulates the activity of the fosB promoter
26. Candidate proto-oncogene bcl-3 encodes a subunit-specific inhibitor of transcription factor NF-kappa B
27. Isolation, sequencing, and mapping of the human homologue of the yeast transcription factor, SPT5
28. Loss of cell cycle regulators p27(Kip1) and cyclin E in transitional cell carcinoma of the bladder correlates with tumor grade and patient survival