Chromosome 17 aneusomy detected by fluorescence in situ hybridization in vulvar squamous cell carcinomas and synchronous vulvar skin

American Journal of Pathology

Volumn 157, Issue 3, 2000, Pages 973-983

  Carlson, J Andrew ^a   Healy, Kara ^a   Tran, Tien Anh ^a   Malfetano, John ^a   Wilson, Vincent L ^b   Rohwedder, Angela ^c   Ross, Jeffrey S ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

^b LOUISIANA STATE UNIVERSITY   (United States)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

KI 67 ANTIGEN;

ADULT; AGED; ANEUPLOIDY; ARTICLE; CARCINOGENESIS; CARCINOMA IN SITU; CHROMOSOME 17; CHROMOSOME DAMAGE; CLINICAL ARTICLE; CONTROLLED STUDY; DNA CONTENT; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KARYOTYPE; LICHEN SCLEROSUS ET ATROPHICUS; NEURODERMATITIS; POLYSOME; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; VULVA; VULVA CARCINOMA;

EID: 0034492981     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64610-X     Document Type: Article

References (70)

1. Pathobiology of vulvar squamous neoplasia
2. Vulvar lichen sclerosus and squamous cell carcinoma: A cohort, case control, and investigational study with historical perspective: Implications for chronic inflammation and sclerosis in the development of neoplasia
3. The under-reporting of skin disease in association with squamous cell carcinoma of the vulva
4. A genetic model for colorectal tumorigenesis
5. Mutator phenotype may be required for multistage carcinogenesis
6. Genetic instabilities in human cancers
7. Genetic instability of cancer cells is proportional to their degree of aneuploidy
8. Genetic instabilities of chromosome 9, 17 and accumulation of p53 overexpression during multistage tumorigesis in head and neck cancer
9. Flow-cytometric DNA content analysis of esophageal squamous cell carcinomas
10. Increased polysomies of chromosomes 7 and 17 during head and neck multistage tumorigenesis
11. Chromosome changes in a squamous cell carcinoma of the vagina
12. Duplication of the long arm of chromosome 1 in a malignant vaginal tumour
13. Karyotypic findings in tumors of the vulva and vagina
14. Bowenoid papulosis showing polyclonal nature
15. Consistent chromosome abnormalities in squamous cell carcinoma of the vulva
16. Chromosomes of condyloma acuminatum, Paget's disease, in situ carcinoma, invasive squamous cell carcinoma and malignant melanoma of the human vulva
17. Intraepithelial squamous lesions of the vulva: Biologic and histologic criteria for the distinction of condylomas from vulvar intraepithelial neoplasia
18. Evaluation of prognostic indicators in squamous carcinoma of the vulva including nuclear DNA content
19. Human papillomavirus type 16 in intraepithelial neoplasia (bowenoid papulosis) and coexistent invasive carcinoma of the vulva
20. Detection of p53 and K-ras base pair mutations in vulvar lichen sclerosus
21. Presence and persistence of HPV infection and p53 mutation in cancer of the cervix uteri and the vulva
22. Mutation of tumor suppressor gene p53 is frequently found in vulvar carcinoma cells
23. Carcinoma of the vulva: HPV and p53 mutations
24. The p53 tumor suppressor gene frequently is altered in gynecologic cancers
25. Papillomavirus, p53 alteration, and primary carcinoma of the vulva
26. p53 mutations and clonality in vulvar carcinomas and squamous hyperplasias: Evidence suggesting that squamous hyperplasias do not serve as direct precursors of human papillomavirus-negative vulvar carcinomas
27. Status of the p53 tumor suppressor gene in human squamous carcinoma cell lines
28. p53 expression and polysomies of chromosome 9, 17 in head and neck cancer prognosis
29. Chromosome 17 abnormalities in squamous cell carcinoma of the oral cavity, and its relationship with p53 and Bcl-2 expression
30. Molecular cytogenetic fingerprinting of esophageal squamous cell carcinoma by comparative genomic hybridization reveals a consistent pattern of chromosomal alterations
31. Interphase cytogenetic evidence for distinct genetic pathways in the development of squamous neoplasia of the uterine cervix
32. Basal cell carcinomas and squamous cell carcinomas of human skin show distinct patterns of chromosome loss
33. A susceptibility locus for epidermodysplasia verruciformis, an abnormal predisposition to infection with the oncogenic human papillomavirus type 5, maps to chromosome 17qter in a region containing a psoriasis locus
34. Probable nonpapillomavirus etiology of squamous cell carcinoma of the vulva in older women: A clinicopathologic study using in situ hybridization and polymerase chain reaction
35. Report on the ISSVD terminology committee
36. Normal histology and nomenclature of the vulva, and malignant neoplasms, including VIN
37. Algorithmic method for diagnosis that employs pattern analysis
38. Detection of genomic changes in cancer by in situ hybridization
39. Assesment of intra-tumoral karyotypic heterogeneity by interphase cytogenetic in paraffin wax sections
40. Analysis of alterations adjacent to invasive vulvar carcinoma and their relationship with the associated carcinoma: A study of 67 cases
41. Monoclonal origin of vulvar intraepithelial neoplasia and some vulvar hyperplasias
42. Monoclonal antibodies against recombinant parts of the Ki-67 antigen (MIB 1 and MIB 3) detect proliferating cells in microwave-processed formalin-fixed paraffin sections
43. Interphase cytogenetics: Analysis of numerical chromosome aberrations in isolated cells
44. Human papilloma virus, vulvar dystrophy, and vulvar carcinoma: Differential expression of human papillomavirus and vulvar dystrophy in the presence and absence of squamous cell carcinoma of the vulva
45. Human papillomavirus (HPV) in vulvar dysplasia and carcinoma in situ
46. HPV-16 viral transcripts in vulvar neoplasia: Preliminary studies
47. Mechanisms of tumor progression
48. Genetic instability in colorectal cancers
49. Mutations of mitotic checkpoint genes in human cancers
50. How aneuploidy affects metabolic control and causes cancer
51. Chromosome error propagation and cancer
52. A flow cytometric study of the significance of DNA aneuploidy in cutaneous lesions
53. Recurrent squamous cell carcinoma of the vulva: A study of 73 cases
54. Second primary cancers in patients with squamous cell carcinoma of the skin: A population-based study in Sweden
55. "Field cancerization" in oral stratified squamous epithelium. Clinical implications of multicentric origin
56. Second primary malignancies following diagnosis of small-cell lung cancer
57. Comparative immunophenotypic study of lichen sclerosus: Epidermotropic CD57+ lymphocytes are numerous - Implications for pathogenesis
58. Genetic changes during the multistage pathogenesis of human papillomavirus positive and negative vulvar carcinomas
59. Molecular mechanisms for inflammation-promoted pathogenesis of cancer - The Sixteenth International Symposium of the Sapporo Cancer Seminar
60. Schistosomiasis and malignancy
61. Numerical aberrations of chromosomes 7, 9 and 17 in squamous cell and transitional cell cancer of the bladder: A comparative study performed by fluorescence in situ hybridization
62. Cervical cytology by means of fluorescence in situ hybridization with a set of chromosome-specific DNA probes
63. Precancer of the human cervix
64. The human papillomavirus-16 E6 oncoprotein decreases the vigilance of mitotic checkpoints
65. DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function
66. New concepts on the role of human papillomavirus in cell cycle regulation
67. Abrogation of a mitotic checkpoint by E2 proteins from oncogenic human papillomaviruses correlates with increased turnover of the p53 tumor suppressor protein
68. Overriding of cyclin-dependent kinase inhibitors by high and low risk human papillomavirus types: Evidence for an in vivo role in cervical lesions
69. Chromosomal instability is correlated with telomere erosion and inactivation of G2 checkpoint function in human fibroblasts expressing human papillomavirus type 16 E6 oncoprotein