Numerical aberrations of chromosomes 7, 9 and 17 in squamous cell and transitional cell cancer of the bladder: A comparative study performed by fluorescence in situ hybridization

Journal of Urology

Volumn 160, Issue 3 I, 1998, Pages 737-740

  Pycha, Armin ^a   Mian, Christine ^a   Posch, Bernd ^a   Haitel, Andrea ^a   El Baz, Mahmoud ^a   Ghoneim, Mohamed A ^a   Marberger, Michael ^a  

^a NONE

Author keywords

Carcinoma; Chromosome aberration; Genes; p53; Schistosomiasis

Indexed keywords

PROTEIN P53;

ADULT; AGED; ARTICLE; BLADDER CARCINOMA; CANCER CLASSIFICATION; CANCER INVASION; CARCINOGENESIS; CHROMOSOME 17; CHROMOSOME 7; CHROMOSOME 9; CHROMOSOME ABERRATION; CONTROLLED STUDY; CYTOGENETICS; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TRANSITIONAL CELL CARCINOMA;

EID: 0032323514     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5347(01)62772-1     Document Type: Article

References (29)

1. Sandberg, A. A. and Berger, C. S.: Review of chromosome studies in urological tumors. II. Cytogenetics and molecular genetics of bladder cancer. J. Urol., 151: 545, 1994.
2. Warren, W., Biggs, P. J., El-Baz, M., Ghoneim, M. A., Stratton, M. R. and Venitt, S.: Mutations in the p53 gene in schistosomal bladder cancer: a study of 92 tumours from Egyptian patients and a comparison between mutational spectra from schistosomal and non-schistosomal urothelial tumours. Carcinogenesis, 16: 1181, 1995.
3. Gonzalez-Zulueta, M., Shibata, A., Ohneseit, P. F., Spruck, C. H., III, Busch, C., Shamaa, M., El-Baz, M., Nichols, P. W., Gonzalgo, M. L., Malmström, P.-U. and Jones, P. A.: High frequency of chromosome 9p allelic loss and CDKN2 tumor suppressor gene alterations in squamous cell carcinoma of the bladder. J. Natl. Cancer Inst., 87: 1383, 1995.
4. El-Bolkainy, M. N.: Epidemiology of cancer. In: General Pathology of Cancer. Cairo, Egypt: Al-Adehaa Graphic Center, chapt. 3, pp. 47-77, 1989.
5. El Bolkainy, M. N., Mokhtar, N. M., Ghoneim, M. A. and Hussein, M. H.: The impact of schistosomiasis on the pathology of bladder carcinoma. Cancer, 48: 2643, 1981.
6. Ghaleb, A. H., Pizzolo, J. G. and Melamed, M. R.: Aberrations of chromosomes 9 and 17 in bilharzial bladder cancer as detected by fluorescence in situ hybridization. Amer. J. Clin. Path., 106: 234, 1996.
7. Ghoneim, M. A., El-Mekresh, M. M., El-Baz, M. A., El-Attar, I. A. and Ashamallah, A.: Radical cystectomy for carcinoma of the bladder: critical evaluation of the results in 1,026 cases. J. Urol., 158: 393, 1997.
8. Olumi, A. F., Tsai, Y. C., Nichols, P. W., Skinner, D. G., Cain, D. R., Bender, L. I. and Jones, P. A.: Allelic loss of chromosome 17p distinguishes high grade from low grade transitional cell carcinomas of the bladder. Cancer Res., 50: 7081, 1990.
9. Meloni, A. M., Peier, A. M., Haddad, F. S., Powell, I. J., Block, A. M. W., Huben, R. P., Todd, I., Potter, W. and Sandberg, A. A.: A new approach in the diagnosis and follow-up of bladder cancer. FISH analysis of urine, bladder washings, and tumors. Cancer Gen. Cytogen., 71: 105, 1993.
10. Spruck, C. H., III, Ohneseit, P. F., Gonzales-Zulueta, M., Esrig, D., Miyao, N., Tsai, Y. C., Lerner, S. P., Schmütte, C., Yang, A. S., Cote, R., Dubeau, L., Nichols, P. W., Hermann, G. G., Steven, K., Horn, T., Skinner, D. G. and Jones, P. A.: Two molecular pathways to transitional cell carcinoma of the bladder. Cancer Res., 54: 784, 1994.
11. Ruppert, J. M., Tokino, K. and Sidransky, D.: Evidence for two bladder cancer suppressor loci on human chromosome 9. Cancer Res., 53: 5093, 1993.
12. Waldman, F. M., Caroll, P. R., Kerschmann, R., Cohen, M. B., Field, F. G. and Mayall, B. H.: Centromeric copy number of chromosome 7 is strongly correlated with tumor grade and labeling index in human bladder cancer. Cancer Res., 51: 3807, 1991.
13. Wheeless, L. L., Reeder, J. E., Han, R., O'Connell, M. J., Frank, I. N., Cockett, A. T. and Hopman, A. H.: Bladder irrigation specimens assayed by fluorescence in situ hybridization to interphase nuclei. Cytometry, 17: 319, 1994.
14. Pauwels, R. P., Schapers, R. F. M., Smeets, W. G. B., Debruyne, F. M. J. and Geraedts, J. P. M.: Grading in superficial bladder cancer. (1). Morphological criteria. Brit. J. Urol., 61: 129, 1988.
15. Thomas, D. J., Robinson, M. C., Charlton, R., Wilkinson, S., Shenton, B. K. and Neal, D. E.: p53 expression, ploidy and progression in pT1 transitional cell carcinoma of the bladder. Brit. J. Urol., 73: 533, 1994.
16. Sauter, G., Deng, G., Moch, H., Kerschmann, R., Matsumura, K., De Vries, S., George, T., Fuentes, J., Caroll, P., Mihatsch, M. J. and Waldman, F. M.: Physical deletion of the p53 gene in bladder cancer. Detection by fluorescence in situ hybridization. Amer. J. Path., 144: 756, 1994.
17. Levine, A. J., Momand, J. and Finlay, C. A.: The p53 tumor suppressor gene. Nature, 351: 453, 1991.
18. Mellon, K., Wilkinson, S., Vickers, J., Robinson, M. C., Shenton, B. K. and Neal, D. E.: Abnormalities in p53 and DNA content in transitional cell carcinoma of the bladder. Brit. J. Urol., 73: 522, 1994.
19. Kamel, D., Soini, Y., Khalifa, A., Mangoud, A., Vähäkangas, K. and Pääkkö, P.: p53 and c-erbB-2 expression in schistosomal urinary bladder carcinomas and schistosomal cystitis with premalignant lesions. Virch. Arch., 424: 349, 1994.
20. Chaudhary, K. S., Lu, Q. L., Abel, P. D., Khandan-Nia, N., Shoma, A. M., El Baz, M., Stamp, G. W. H. and Lalani, E. N.: Expression of bcl-2 and p53 oncoproteins in schistosomiasis-associated transitional and squamous cell carcinoma of the bladder. Brit. J. Urol., 79: 78, 1997.
21. Sobin, L. H. and Wittekind, Ch.: TNM Classification of Malignant Tumours, 5th ed. New York: Springer Verlag, 1997.
22. Hedley, D. W., Friedlander, M. I., Taylor, I. W., Rugg, C. A. and Musgrove, E. A.: Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry. J. Histochem. Cytochem., 31: 1333, 1983.
23. Pycha, A., Mian, C., Haitel, A., Hofbauer, J., Wiener, H. and Marberger, M.: Fluorescence in situ hybridization identifies more aggressive types of primarily non invasive (stage pTa) bladder cancer. J. Urol., 157: 2116, 1997.
24. Lemmer, L. B. and Fripp, P. J.: Schistosomiasis and malignancy. S. Afr. Med. J., 84: 211, 1994.
25. Rosin, M. P., Anwar, A. A. and Ward, A. J.: Inflammation, chromosomal instability, and cancer: the schistosomiasis model. Cancer Res., suppl., 54: 1929S, 1994.
26. Cairns, P., Tokino, K., Eby, Y. and Sidransky, D.: Homozygous deletions of 9p21 in primary human bladder tumors detected by comparative multiplex polymerase chain reaction. Cancer Res., 54: 1422, 1994.
27. Miyao, N., Tsai, Y. C., Lerner, S. P., Olumni, A. F., Spruck, C. H., III, Gonzalez-Zulueta, M., Nichols, P. W., Skinner, D. G. and Jones, P. A.: Role of chromosome 9 in human bladder cancer. Cancer Res., 53: 4066, 1993.
28. Keen, A. J. and Knowles, M. A.: Definition of two regions of deletion on chromosome 9 in carcinoma of the bladder. Oncogene, 9: 2083, 1994.
29. Sidransky, D., Von Eschenbach, A., Tsai, Y. C., Jones, P., Summerhayes, I., Marshall, F., Paul, M., Green, P., Hamilton, S. R. and Frost, P.: Identification of p53 gene mutations in bladder cancers and urine samples. Science, 252: 706, 1991.