Effects of endotoxin-induced fever and probenecid on disposition of enrofloxacin and its metabolite ciprofloxacin after intravascular administration of enrofloxacin in goats

Journal of Veterinary Pharmacology and Therapeutics

Volumn 23, Issue 6, 2000, Pages 365-372

  Rao, G S ^a   Ramesh, S ^a   Ahmad, A H ^b   Tripathi, H C ^a,b   Sharma, L D ^b   Malik, J K ^c  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

^b G B PANT UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (India)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CIPROFLOXACIN; DRUG METABOLITE; ENDOTOXIN; ENROFLOXACIN; FLOXIDIN; PROBENECID;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; COMPARTMENT MODEL; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG HALF LIFE; DRUG METABOLISM; FEMALE; FEVER; GOAT; INJECTION; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTI-INFECTIVE AGENTS; AREA UNDER CURVE; CIPROFLOXACIN; DRUG INTERACTIONS; ENDOTOXINS; FEMALE; FEVER; FLUOROQUINOLONES; GOATS; HALF-LIFE; INJECTIONS, INTRAVENOUS; METABOLIC CLEARANCE RATE; PROBENECID; QUINOLONES; URICOSURIC AGENTS;

EID: 0034492438     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2885.2000.00295.x     Document Type: Article

References (37)

1. Chemotherapy and pharmacokinetics of some antimicrobial agents in healthy dwarf goats and those infected with Ehrlichia phagocytophilia (tick-borne fever)
2. Principles of drug disposition in domestic animals
3. Pharmacokinetics of enrofloxacin in rabbits
4. Fluoroquinolones in animal health
5. Pharmacokinetics of enrofloxacin given by the oral, intravenous and intramuscular routes in broiler chickens
6. The disposition of five therapeutically important antimicrobial agents in Llamas
7. Pharmacokinetics of enrofloxacin in calves
8. The plasma kinetics and tissue distribution of enrofloxacin and its metabolite, ciprofloxacin in the Muscovy Duck
9. Effect of probenecid on the distribution and elimination of ciprofloxacin in humans
10. Pharmacokinetics of enrofloxacin after single intravenous, intramuscular and subcutaneous injections in lactating cows
11. Pharmacokinetics of enrofloxacin in horses after single intravenous and intramuscular administration
12. Pharmacokinetics of enrofloxacin in newborn and one week old calves
13. Some pharmacokinetic data of aditoprim and trimethoprim in healthy and tick-borne fever infected dwarf goats
14. Influence of experimentally induced theileriosis (Theileria annulata) on the pharmacokinetics of a long-acting formulation of oxytetracycline (OTC-LA) in calves
15. Effects of experimentally induced Theileria annulata infection on the pharmacokinetics of oxytetracycline in cross-bred calves
16. Pharmacokinetics of enrofloxacin and its metabolite, ciprofloxacin after intravenous and oral administrations of enrofloxacin in dogs
17. Disposition of enrofloxacin (Baytril) into the udder after intravenous and intra-arterial injections into dairy cows
18. Pharmacokinetics of enrofloxacin and its metabolite, ciprofloxacin after intravenous and intramuscular administrations in sheep
19. Influence of experimental fever on the plasma levels of sulphadimidine in buffalo calves following oral administration
20. Cytochromes and cytokines: Changes in drug disposition in animals during an acute phase response: A mini review
21. A lipopolysaccharide-induced acute phase response in the pig is associated with a decrease in hepatic cytochrome P450-mediated drug metabolism
22. Comparative pharmacokinetic parameters of new systemic fluoroquinolones: A review
23. Bioavailability of enrofloxacin after oral administration to fed and fasted pigs
24. Enrofloxacin pharmacokinetics after intravenous and intramuscular administration in pigs
25. Pharmacokinetics of enrofloxacin following intravenous/intramuscular/oral administrations in Nedji sheep
26. In vitro susceptibility of selected veterinary bacterial pathogens to ciprofloxacin, enrofloxacin and norfloxacin
27. Is exposure to bacterial endotoxin determinant of susceptibility to intoxication from xenobiotic agents
28. High performance liquid chromatographic method for the simultaneous determination of enrofloxacin and its primary metabolite ciprofloxacin in canine serum and prostatic tissue
29. Effect of staphylococcal enterotoxin-induced diarrhoea on the pharmacokinetics of sulphadimidine in the goat
30. Clinical symptoms induced by E. coli endotoxin in goats
31. Staphylococcal enterotoxin B and Escherichia coli endotoxin: Comparative observations in goats on fever and associated clinical haematologic and blood biochemical changes after intravenous administration
32. Comparative observations of fever and associated clinical, haematological and blood biochemical changes after intravenous administration of Vibrio cholerae enterotoxin, staphylococcal enterotoxins and Escherichia coli endotoxin in goats
33. Pharmacokinetics of quinolones: Newer aspects
34. Pharmacokinetics and bioavailability of enrofloxacin in pigs
35. Effects of experimentally induced Escherichia coli infection on the pharmacokinetics of enrofloxacin in pigs