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Volumn 20, Issue 7, 1997, Pages 776-780

Inhibitory effects of Shouseiryu-to on two-stage carcinogenesis. II. Anti-tumor-promoting activities of lignans from Asiasarum heterotropoides var. mandshuricum

Author keywords

Anti tumor promoter; Asarinin; Asiasarum heterotropoides var. mandshuricum; Lignan; Shouseiryu to; Xanthoxylol

Indexed keywords

ASARININ; LIGNAN; PLANT EXTRACT; SHOUSEIRYU TO; UNCLASSIFIED DRUG; XANTHOXYLOL;

EID: 0030788627     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.20.776     Document Type: Article
Times cited : (56)

References (23)
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    • Berenblum I., Cancer Res., 1, 807-814 (1941); Yamamoto N., Bister K., ZurHausen H., Nature (London), 278, 553-554 (1979); Verma A. K., Slaga T. J., Wertz P. W., Mueller G. C., Boutwell R. K., Cancer Res. 40, 2367-2371 (1980), and references cited therein.
    • (1979) Nature (London) , vol.278 , pp. 553-554
    • Yamamoto, N.1    Bister, K.2    ZurHausen, H.3
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    • and references cited therein
    • Berenblum I., Cancer Res., 1, 807-814 (1941); Yamamoto N., Bister K., ZurHausen H., Nature (London), 278, 553-554 (1979); Verma A. K., Slaga T. J., Wertz P. W., Mueller G. C., Boutwell R. K., Cancer Res. 40, 2367-2371 (1980), and references cited therein.
    • (1980) Cancer Res. , vol.40 , pp. 2367-2371
    • Verma, A.K.1    Slaga, T.J.2    Wertz, P.W.3    Mueller, G.C.4    Boutwell, R.K.5
  • 11
    • 85036486394 scopus 로고    scopus 로고
    • note
    • 1) was identified as Asiasarum sieboldii, the radix of A. heterotropoides var. mandshuricum, which was commercially available and is the most widely used species, is applied in this report.
  • 15
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    • Hashimoto K., Okada M., Maruno M., Natural Medicines, 48, 39-48 (1994): Saiki Y., Fukuyama H., Tsuneya T., Yakugaku Zasshi, 107, 219-226 (1987); Hashimoto K., Katsuhara T., Itoh H., Ikeya Y., Okada M., Mitsuhashi H., Phytochemistry, 29, 3571-3574 (1990).
    • (1994) Natural Medicines , vol.48 , pp. 39-48
    • Hashimoto, K.1    Okada, M.2    Maruno, M.3
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    • Hashimoto K., Okada M., Maruno M., Natural Medicines, 48, 39-48 (1994): Saiki Y., Fukuyama H., Tsuneya T., Yakugaku Zasshi, 107, 219-226 (1987); Hashimoto K., Katsuhara T., Itoh H., Ikeya Y., Okada M., Mitsuhashi H., Phytochemistry, 29, 3571-3574 (1990).
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    • Saiki, Y.1    Fukuyama, H.2    Tsuneya, T.3
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    • note
    • In our experiments, when the same amount of glycyrrhetic acid (85 nmol) as 6 or 7 was applied, more than 95% of the mice bore papillomas at 18 weeks of promotion and about 7 papillomas were formed per mouse after 20 weeks of promotion (in the positive control group, 100% of mice bore papillomas at 10 weeks of promotion and more than 10 papillomas were formed per mouse after 20 weeks of promotion, the same as in this report).
  • 23
    • 85036492616 scopus 로고    scopus 로고
    • note
    • 1)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.