Nitric oxide damages neuronal mitochondria and induces apoptosis in neurons

Chinese Science Bulletin

Volumn 45, Issue 5, 2000, Pages 422-426

  Wei, T ^a   Chen, C ^a   Hou, J ^a   Zhao, B ^a   Xin, W ^a  

^a INSTITUTE OF BIOPHYSICS   (China)

Author keywords

Apoptosis; Cerebellar granule cells; Mitochondria; Nitric oxide

Indexed keywords

N ACETYL S NITROSOPENICILLAMINE; NITRIC OXIDE; NITRIC OXIDE DONOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; FLOW CYTOMETRY; GRANULE CELL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MITOCHONDRION; NERVE CELL; NERVE POTENTIAL; NEUROTOXICITY; NONHUMAN; RAT;

ANIMALIA;

EID: 0034488473     PISSN: 10016538     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02884942     Document Type: Article

References (12)

1. NO at work
2. Apoptotic features of selective neuronal death in ischemia, epilepsy and gp120 toxicity
3. Apoptosis in the pathogenesis and treatment of disease
4. A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
5. EPC-K1 attenuates peroxynitrite-induced apoptosis in cerebellar granule cells
6. +-ATPase activity in hippocampal neurons
7. + content, and p53 accumulation
8. Nitric oxide-mediated mitochondrial damage: A potential neuroprotective role for glutathione
9. Persistent inhibition of cell respiration by nitric oxide: Crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione
10. Hypothesis: Control of apoptosis by the cellular ATP level
11. Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondria particles
12. Mitochondria, free radicals, and neurodegeneration