Genetic linkage of Kozak sequence polymorphism of the platelet glycoprotein Ibα with human platelet antigen-2 and variable number of tandem repeats polymorphism, and its relationship with coronary artery disease

British Journal of Haematology

Volumn 111, Issue 4, 2000, Pages 1247-1249

  Ishida, Fumihiro ^a   Ito, Toshiro ^a,b   Takei, Manabu ^a   Shimodaira, Shigetaka ^a   Kitano, Kiyoshi ^a   Kiyosawa, Kendo ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGANO RED CROSS HOSPITAL   (Japan)

Author keywords

Glycoprotein Ib; Kozak sequence; Linkage; Polymorphism; Thrombosis

Indexed keywords

CYTOSINE; GLYCOPROTEIN IB; THROMBOCYTE ANTIGEN;

ALLELE; ARTICLE; ASIAN; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; DNA POLYMORPHISM; GENE EXPRESSION; GENE FREQUENCY; GENETIC LINKAGE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; TANDEM REPEAT; THROMBOCYTE;

ADULT; ANTIGENS, HUMAN PLATELET; CASE-CONTROL STUDIES; CHI-SQUARE DISTRIBUTION; CHROMOSOME MAPPING; CORONARY DISEASE; HUMANS; JAPAN; KOREA; LINKAGE (GENETICS); LOGISTIC MODELS; MIDDLE AGED; MINISATELLITE REPEATS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX;

EID: 0034487602     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.02479.x     Document Type: Article

References (13)

1. Polymorphism of the platelet glycoprotein (GP) Ibα Kozak sequence determines the surface level of the GPIb-V-IX complex and risk for early myocardial infarction
2. Kozak sequence polymorphism of the glycoprotein (GP) Ibα gene is a major determinant of the plasma membrane levels of the platelet GP Ib-IX-V complex
3. Polymorphisms of the human platelet antigens HPA-1, HPA-2, and HPA-5 on the platelet receptors for fibrinogen (GPIIb/IIIa), von Willebrand factor (GPIb/IX), and Collagen (GPIa/IIa) are not correlated with an increased risk for stroke
4. New alleles of the platelet glycoprotein Ibα gene
5. A common polymorphism flanking the ATG initiator codon of GPIbα does not affect expression and is not a major risk factor for arterial thrombosis
6. Polymorphisms of platelet membrane glycoprotein Ibα associated with arterial thrombotic disease
7. 145
8. Polymorphisms of platelet membrane glycoprotein Ibα and plasma von Willebrand factor antigen in coronary artery disease
9. Systemic screening for genetic polymorphism in human platelet glycoprotein Ib alpha
10. The platelet glycoprotein Ib-IX complex
11. Genetic and structural characterization of an amino acid dimorphism in glycoprotein Ibα involved in platelet transfusion refractoriness
12. Coronary artery disease and polymorphisms in a receptor mediating shear stress-dependent platelet activation
13. Structure of the human platelet membrane glycoprotein Ibα gene