Structural and biochemical properties show ARL3-GDP as a distinct GTP binding protein

Structure

Volumn 8, Issue 12, 2000, Pages 1239-1245

  Hillig, R C ^a   Hanzal Bayer, M ^a   Linari, M ^a   Becker, J ^a   Wittinghofer, A ^a   Renault, L ^a  

^a MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

Arf like protein; GTP binding; Intracellular trafficking; Ras superfamily

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MAGNESIUM ION; RAS PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; HYDROPHOBICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

ADP-RIBOSYLATION FACTOR 1; ADP-RIBOSYLATION FACTORS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; GTP-BINDING PROTEINS; GUANOSINE DIPHOSPHATE; MAGNESIUM; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SEQUENCE HOMOLOGY, AMINO ACID;

MURINAE;

EID: 0034476959     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(00)00531-1     Document Type: Article

References (33)

1. The arflike gene encodes an essential GTP-binding protein in Drosophila
2. Purification of a protein cofactor required for ADP-ribosylation of the stimulatory regulatory component of adenylate cyclase by cholera toxin
3. Molecules in the Arf orbit
4. The role of Arf and Rab GTPases in membrane transport
5. An ADP-ribosylation-factor(Arf)-like protein involved in regulated secretion
6. The delta subunit of rod specific cyclic GMP phosphodiesterase, PDE delta, interacts with the Arf-like protein Arl3 in a GTP specific manner
7. The Arf-like 2 (ARL2)-binding protein, BART: Purification, cloning, and initial characterization
8. The retinitis pigmentosa GTPase regulator, RPGR, interacts with the delta subunit of rod cyclic GMP phosphodiesterase
9. Crystal structures at 2.2 Å resolution of the catalytic domains of normal Ras protein and an oncogenic mutant complexed with GDP
10. Structure of the human ADP-ribosylation factor 1 complexed with GDP
11. The structure of rat ADP ribosylation factor-1 (Arf 1) complexed to GDP determined from two different crystal forms
12. Crystal structure of the nuclear Ras-related protein Ran in its GDP-bound form
13. An α to β conformational switch in EF-Tu
14. Structural basis for activation of Arf GTPase: Mechanisms of guanine nucleotide exchange and GTP-myristoyl switching
15. Preparation of recombinant ADP-ribosylation factor
16. Lipid modification at the N-terminus of photoreceptor G-protein α subunit
17. The Ras protein family: Evolutionary tree and role of conserved amino acids
18. Helix unwinding in the effector region of elongation factor EF-Tu-GDP
19. 2+ and the beta-phosphate to destabilize GDP on Arf1
20. Nucleotide binding and cofactor activities of purified bovine brain and bacterially expressed ADP-ribosylation factor
21. Myristoylation is not required for GTP-dependent binding of ADP-ribosylation factor Arf1 to phospholipids
22. Structure of Arf6-GDP suggests a basis for guanine nucleotide exchange factor specificity
23. 2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteins
24. The functioning of molecular switches in three dimensions
25. ADP-ribosylation factor (Arf)-like 4, 6, and 7 represent a subgroup of the Arf family characterized by rapid nucleotide exchange and a nuclear localization signal
26. Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants
27. AMoRe: An automated molecular replacement package
28. Crystallography & NMR system: A new software suite for macromolecular structure determination
29. Model building and refinement practice
30. BRAGI: A comprehensive protein modelling program system
31. MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures
32. Further additions to MolScript version 1.4, including reading and contouring of electron-density maps
33. Raster3D: Photorealistic molecular graphics