Particle-mediated gene therapy of wounds

Wound Repair and Regeneration

Volumn 8, Issue 6, 2000, Pages 452-459

  Davidson, J M ^a   Krieg, T ^a   Eming, S A ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DNA; GENE PRODUCT; GROWTH FACTOR; GROWTH FACTOR RECEPTOR; VIRUS ANTIGEN;

ARTICLE; BIOAVAILABILITY; DEVICE; DNA TRANSFER; DRUG DELIVERY SYSTEM; DRUG STABILITY; GENE GUN; GENE TARGETING; GENE THERAPY; HUMAN; PRIORITY JOURNAL; TISSUE INJURY; WOUND HEALING IMPAIRMENT;

DRUG CARRIERS; EQUIPMENT DESIGN; GENE THERAPY; GENE TRANSFER TECHNIQUES; GROWTH SUBSTANCES; HUMANS; SENSITIVITY AND SPECIFICITY; WOUND HEALING; WOUNDS AND INJURIES;

EID: 0034476851     PISSN: 10671927     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1524-475X.2000.00452.x     Document Type: Article

References (58)

1. Human gene therapy
2. Prospects for human gene therapy
3. Gene therapy of wounds with growth factors
4. Wound healing - Aiming for perfect skin regeneration
5. Cutaneous wound healing
6. Cellular and biochemical mechanisms of wound repair
7. Chronic wounds: Pathophysiologic and experimental considerations
8. Growth factors and chronic wounds: The need to understand the microenvironment
9. Growth factors and wound healing: Biochemical properties of growth factors and their receptors
10. Growth factors and wound healing: Part II. Role in normal and chronic wound healing
11. Pharmacologic enhancement of wound healing
12. Expression and proteolysis of vascular endothelial growth factor is increased in chronic wounds
13. Gene therapy for tissue repair: Approaches and prospects
14. Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes
15. Targeted expression of insulin-like growth factor to human keratinocytes: Modification of the autocrine control of keratinocyte proliferation
16. Genetically modified human epidermis overexpressing PDGF-A directs the development of a cellular and vascular connective tissue stroma when transplanted to athymic mice - Implications for the use of genetically modified keratinocytes to modulate dermal regeneration
17. Retrovirus-mediated transduction of cultured epidermal keratinocytes
18. Particle-mediated gene transfer of granulocyte-macrophage colony- stimulating factor cDNA to tumor cells: Implications for a clinically relevant tumor vaccine
19. A brief history of gene therapy
20. Adenoviral-mediated overexpression of platelet-derived growth factor-B corrects ischemic impaired wound healing
21. Expression of adenovirally delivered gene products in healing osseous tissues
22. FGF2-targeted adenovirus encoding platelet-derived growth factor-B enhances de novo tissue formation
23. Gene therapeutics
24. A DNA controlled-release coating for gene transfer: Transfection in skeletal and cardiac muscle
25. DNA delivery from polymer matrices for tissue engineering
26. Potential role for direct gene transfer in the enhancement of fracture healing
27. High-efficiency transformation of mammalian cells by plasmid DNA
28. Factors influencing the enhancement of the infectivity of poliovirus ribonucleic acid by diethylaminoethyl-dextran
29. Gene transfer into mouse lyoma cells by electroporation in high electric fields
30. High efficiency transformation by direct microinjection of DNA into cultured mammalian cells
31. Puncture-mediated gene transfer to the skin
32. In vivo gene transfer to skin and wound by microseeding
33. High-velocity microprojectiles for delivering nucleic acids into living cells
34. Gene transfer into mammalian somatic cells in vivo
35. Gene gun and other non-viral approaches for cancer gene therapy
36. Methods for particle-mediated gene transfer into skin
37. In vivo and in vitro gene transfer to mammalian somatic cells by particle bombardment
38. Particle-mediated gene transfer with transforming growth factor-betal cDNAs enhances wound repair in rat skin
39. Boosting epidermal growth factor receptor expression by gene gun transfection stimulates epidermal growth in vivo
40. In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment
41. Particle-mediated gene transfer of PDGF isoforms promotes wound repair
42. A model for keratinocyte gene therapy: Preclinical and therapeutic considerations
43. In vivo transfer and expression of a human epidermal growth factor gene accelerates wound repair
44. Transfection with aFGF cDNA improves wound healing
45. Targeting expression with light using caged DNA
46. Genetic vaccines
47. DNA vaccination against influenza viruses: A review with emphasis on equine and swine influenza
48. The use of microparticle injection to introduce genes into animal cells in vitro and in vivo
49. DNA vaccines: A novel approach to immunization
50. Interferon-alpha gene therapy for cancer: Retroviral transduction of fibroblasts and particle-mediated transfection of tumor cells are both effective strategies for gene delivery in murine tumor models
51. DNA immunization targeting the skin: Molecular control of adaptive immunity
52. Successful culture and selection of cytokine gene-modified human dermal fibroblasts for the biologic therapy of patients with cancer
53. Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors
54. In vivo incisional wound healing augmented by platelet-derived growth factor and recombinant c-sis gene homodimeric proteins
55. Photonic detection of bacterial pathogens in living hosts
56. Bioluminescent indicators in living mammals
57. A potent far-up-stream enhancer in the mouse pro alpha2(I) collagen gene regulates expression of reporter genes in transgenic mice
58. Nitric oxide inhibition induces early activation of type I collagen gene in renal resistance vessels and glomeruli in transgenic mice. Role of endothelin