Kinetic studies of the reactions of some metal reconstituted metallothioneins with the electrophilic disulfide 5,5′-dithiobis(2-nitrobenzoic acid) (DTNB)

BioMetals

Volumn 13, Issue 4, 2000, Pages 295-300

  Xing, B ^a   Shi, Y ^a   Tang, W ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Cluster structure; Metallothionein; Observed rate constant

Indexed keywords

5,5' DITHIOBIS(2 NITROBENZOIC ACID); BISMUTH; DISULFIDE; METAL ION; METALLOTHIONEIN; PLATINUM; ZINC;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION KINETICS; MATHEMATICAL MODEL; PROTEIN STRUCTURE;

ANIMALS; BISMUTH; DISULFIDES; DITHIONITROBENZOIC ACID; KINETICS; METALLOTHIONEIN; METALS; PLATINUM; RABBITS; ZINC;

ORYCTOLAGUS CUNICULUS;

EID: 0034473044     PISSN: 09660844     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009201325771     Document Type: Article

References (33)

1. 7] MT-2a in aqueous solution determined by nuclear magnetic resonance
2. Spectroscopic studies and characterization of metallothioneins containing mercury, lead and bismuth
3. Cadmium binding and metal cluster formation in MT: A differential modification study
4. Micromolar protein concentrations and metalloprotein stoichiometries obtained by inductively coupled plasma atomic emission spectrometric determined of sufur
5. Gram scales purification and preparation of rabbit liver zinc metallothionein
6. Increased resistance to chlorambucil in cultured cells with a high concentration of cytoplasmic metallothionein
7. 7MT-II by Fourier Transform Infrared Spectroscopy
8. Interleukin 1 regulates human metallothionein gene expression
9. On the reactivity of metallothioneins with 5,5′-dithiobis-(2-nitrobenzoic acid)
10. A cadmium protein from equine kidney cortex
11. Oxidative metal release from metallothionein via zinc-thiol/disulfide interchange
12. Reactions of electrophilic reagents that target the thiolate groups of the metallothionein clusters: Preferential reaction of the α-domain with 5,5′-dithiobis-(2-nitrobenzoate)(DTNB) and aurothiomalate (AuSTm)
13. Prevention of lethal and renal toxicity of cis-diamminedichloroplatinum (II) by induction of metallothionein synthesis withihout compromising its antitumor activity in mice
14. On the role of metallothionein in cadmium induced renal toxicity
15. Structural characterization of metallothionein by muti-nuclear NMR
16. Multiple-quantum cadmium-113-proton correlation spectroscopy as a probe of metal coordination environments in metalloproteins
17. Structure-reactivity relationships of metallothionein, a unique metal-binding protein
18. Properties of the reaction of cis-dichlorodiammineplatinum (II) with metallothionein
19. Refined crystal structure of cadmium-zinc metallothionein at Å resolution
20. Protective role of metallothionein in renal toxicity of cis-platinum
21. On the rapid, monophasic reaction of the rabbit liver metallothionein α-domain with 5,5′-dithiobis-(2-nitrobenzoate)(DTNB)
22. Interactions of bismuth complexes with metallothionein (II)
23. Possible role for metallothionein in protection against radiation-induced oxidative stress: Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals
24. Metallothionein: A novel class of diamagnetic metal-thiolate cluster proteins
25. Structure studies of platinothioneins by using Extended X-Ray Absorption Fine Structure Spectroscopy
26. The in vivo and in vitro binding of platinum to metallothionein
27. Interaction of cis- and trans-diamminedichloroplatinum with metallothione in in vivo
28. Interaction of sodium chloroplatinate and iproplatin with metallothionein in vivo
29. Electrostatic influence on the kinetics of the reaction of lobster metallothioneins with the electrophilic disulfides 2,2′-dithiodipyridine (PyssPy) and 5,5′-dithiobis-(2-nitrobenzoic acid) (ESSE)