Dipeptidyl peptidase IV in inflammatory CNS disease

Advances in Experimental Medicine and Biology

Volumn 477, Issue , 2000, Pages 145-153

  Steinbrecher, Andreas ^a   Reinhold, Dirk ^b   Quigley, Laura ^a   Gado, Ameer ^a   Tresser, Nancy ^a   Izikson, Leonid ^a   Born, Ilona ^c   Faust, Jürgen ^c   Neubert, Klaus ^c   Martin, Roland ^a   Ansorge, Siegfried ^b   Brocke, Stefan ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b OTTO VON GUERICKE UNIVERSITY   (Germany)

^c MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Autoimmune disease; Dipeptidyl peptidase IV (DP IV, CD26); Experimental autoimmune encephalomyelitis; Inhibitors; T cell

Indexed keywords

CYTOKINE; DIPEPTIDYL PEPTIDASE IV; DIPEPTIDYL PEPTIDASE IV INHIBITOR; ENZYME INHIBITOR; MYELIN; UNCLASSIFIED DRUG;

ALLERGIC ENCEPHALOMYELITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME INHIBITION; FEMALE; IMMUNOPATHOGENESIS; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANIMALS, OUTBRED STRAINS; ANTIGENS, CD26; AUTOIMMUNE DISEASES; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FEMALE; HUMANS; LYMPHOCYTE ACTIVATION; LYSINE; MICE; MULTIPLE SCLEROSIS; MYELIN BASIC PROTEINS; PYRROLIDINES; RATS; SERINE PROTEINASE INHIBITORS; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; THIAZOLES;

ANIMALIA;

EID: 0034472913     PISSN: 00652598     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Isolation and characterization of autoreactive T cells in experimental autoimmune encephalomyelitis of the mouse
2. CD26, let it cut or cut it down
3. Amino acid homology between the encephalitogenic site of myelin basic protein and virus: Mechanism for autoimmunity
4. Identification of high potency microbial and self ligands for a human autoreactive class II-restricted T cell clone
5. Dipeptidyl peptidase IV: A cell surface peptidase involved in regulating T cell growth
6. Chemokine regulation of inflammatory-mediated nervous system diseases
7. Chemokine regulation of experimental autoimmune encephalomyelitis: Temporal and spatial expression patterns govern disease pathogenesis
8. A very high level of crossreactivity is an essential feature of the T -cell receptor
9. The structure and function of CD26 in the T-cell immune response
10. + T-cell subsets in autoimmunity
11. Dipeptidyl peptidase IV (CD26) on human lymphocytes. Synthetic inhibitors of and antibodies against dipeptidyl peptidase IV suppress the proliferation of pokeweed mitogen-stimulated peripheral blood mononuclear cells and IL-2 and IL-6 production
12. Inhibitors of dipeptidyl peptidase IV induce secretion of transforming growth factor-β1 in PWM-stimulated PBMC and T cells
13. Inhibitors of dipeptidyl peptidase IV (DP IV, CD26) induces secretion of transforming growth factor-β1 (TGF-β1) in stimulated mouse splenocytes and thymocytes
14. Dipeptidyl peptidase IV of human lymphocytes. Evidence for specific hydrolysis of glycylprolin in T-lymphocytes
15. The role of dipeptidyl peptidase IV in human T lymphocyte activation. Inhibitors and antibodies against dipeptidyl peptidase IV suppress lymphocyte proliferation and immunoglobulin synthesis in vitro
16. Dipeptidyl-peptidase IV/CD26 on T cells: Analysis of an alternative T-cell activation pathway
17. Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein