Inactivation of interleukin-6 by neutrophil proteases at sites of inflammation: Protective effects of soluble IL-6 receptor chains

Advances in Experimental Medicine and Biology

Volumn 477, Issue , 2000, Pages 431-437

  Bank, Ute ^a   Kuüpper, Bernadette ^a   Ansorge, Siegfried ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Cathepsin G; Elastase; Interleukin 6; PMN; Proteinase 3; Soluble receptors

Indexed keywords

CATHEPSIN G; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MEMBRANE METALLOENDOPEPTIDASE; MYELOBLASTIN; PROTEINASE;

CONFERENCE PAPER; CYTOKINE RELEASE; HUMAN; HUMAN CELL; IMMUNOCHEMISTRY; INFLAMMATION; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ACUTE DISEASE; ASCITIC FLUID; CATHEPSINS; CELL-FREE SYSTEM; EXUDATES AND TRANSUDATES; HUMANS; INFLAMMATION; INTERLEUKIN-6; LEUKOCYTE ELASTASE; MYELOBLASTIN; NEUTROPHILS; PLEURAL EFFUSION; RECEPTORS, INTERLEUKIN-6; SERINE ENDOPEPTIDASES; SOLUBILITY; SYNOVIAL FLUID;

FELIS CATUS;

EID: 0034471706     PISSN: 00652598     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Effect of interleukin-6 (IL-6) and transforming growth factor- (TGF-b) on neutrophil elastase release
2. Converting enzyme-independent release of tumor necrosis factor alpha and IL-Ibeta from a stimulated human monocytic cell line in the presence of activated neutrophils or purified proteinase 3
3. Interleukin-8 processing by neutrophil elastase, cathepsin G and proteinase 3
4. Subcellular localization and dynamics of Mac-1 (alpha m beta 2) in human neutrophils
5. 1.9 A crystal structure of interleukin 6: Implications for a novel mode of receptor dimerization and signaling
6. IL-6 and APPs: Anti-inflammatory and immunosuppression mediators