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Volumn 17, Issue 12, 2000, Pages 1531-1536

A population approach to enzyme characterization and identification: Application to phenacetin O-deethylation

(8) Belle, D J a,b Ring, B J a Allerheiligen, S R B a Heathman, M A a O'Brien, L M a Sinha, V a Roskos, L K c Wrighton, S A a

a ELI LILLY AND COMPANY (United States)

b MERCK RESEARCH LABORATORIES (United States)

c Abgenix (United States)

Author keywords

Cytochromes P450; Enzyme kinetics; NONMEM; Phenacetin O deethylation; Sparse sampling

Indexed keywords

CYTOCHROME P450; ETHOXYRESORUFIN; PARACETAMOL; PHENACETIN;

ARTICLE; BIOTRANSFORMATION; CATALYSIS; ENZYME ACTIVITY; ENZYME KINETICS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER MICROSOME; MICHAELIS MENTEN KINETICS; PRIORITY JOURNAL;

ALGORITHMS; ANALGESICS, NON-NARCOTIC; BIOTRANSFORMATION; CYTOCHROME P-450 ENZYME SYSTEM; DEALKYLATION; HUMANS; MICROSOMES, LIVER; MODELS, BIOLOGICAL; PHENACETIN; POPULATION;

EID: 0034468950 PISSN: 07248741 EISSN: None Source Type: Journal
DOI: 10.1023/A:1007665310830 Document Type: Article

Times cited : (10)

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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.