A role for octamer binding protein motifs in the regulation of the proximal preprotachykinin-A promoter

Neuropeptides

Volumn 34, Issue 6, 2000, Pages 348-354

  Fiskerstrand, C E ^a   Newey, P ^a   McGregor, G P ^b   Gerrard, L ^a   Millan, F ^a   Quinn, J P ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; PREPROTACHYKININ;

ARTICLE; CONTROLLED STUDY; ENHANCER REGION; GENE EXPRESSION REGULATION; HELA CELL; HUMAN; HUMAN CELL; NERVE CELL CULTURE; PANCREAS CELL; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; SITE DIRECTED MUTAGENESIS; TRANSCRIPTION REGULATION;

EID: 0034467253     PISSN: 01434179     EISSN: None     Source Type: Journal    
DOI: 10.1054/npep.2000.0828     Document Type: Article

References (17)

1. The molecular biology of preprotachykinin-A gene expression
2. Novel cell lines for the analysis of preprotachykinin-A gene expression identify a repressor domain 3′ of the major transcriptional start site
3. Diversity in mammalian tachykinin peptidergic neurons - Multiple peptides, receptors and regulatory mechanisms
4. Dissociation of Oct-1 from the nuclear peripheral structure induces the cellular aging-associated collagenase gene expression
5. Isolation of a potential neural stem cell line from the internal capsule of an adult transgenic rat brain
6. Transcription factor Oct1 binds to the AT-rich segment of the simian virus 40 replication origin
7. Tachykinins
8. Preprotachykinin-A gene expression occurs transiently in the developing rat endocrine pancreas and can be regulated in RINm5F cells
9. Characterisation of the expression and post-translational processing of the preprotachykinin-I gene and the regulated release of tachykinins by the RINm5F cell-line
10. A role for the octamer-binding protein in preprotachykinin-A gene expression
11. Repression of preprotachykinin-A promoter activity is mediated by a proximal promoter element
12. Conformational alteration of Oct-1 upon DNA binding dictates selectivity in differential interactions with related transcriptional coactivators
13. The opposite and antagonistic effects of the closely related POU family of transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain
14. 5′-Flanking sequences from the rat preprotachykinin gene direct high-level expression of a reporter gene in adult sensory neurons transfected in culture by microinjection
15. A single residue within the homeodomain of the Brn-3 POU family transcription factors determines whether they activate or repress the SNAP-25 promoter
16. Neuronal-specific gene expression - The interaction of both positive and negative transcriptional regulators
17. Autoimmune antigen Ku is enriched on oligonucleotide columns distinct from those containing the octamer binding protein DNA consensus sequence