Conformational alteration of Oct-1 upon DNA binding dictates selectivity in differential interactions with related transcriptional coactivators

Molecular and Cellular Biology

Volumn 16, Issue 8, 1996, Pages 4404-4413

  Misra, Vikram ^a   Walker, Stephen ^b   Yang, Ping ^a   Hayes, Steve ^b   O'Hare, Peter ^b  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b MARIE CURIE RESEARCH INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; DNA BINDING; DNA CONFORMATION; DNA DETERMINATION; DNA SEQUENCE; GENE CONTROL; GENETIC TRANSCRIPTION; HERPES SIMPLEX VIRUS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION;

EID: 0029898424     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.8.4404     Document Type: Article

References (53)

1. apRhys, C. M. J., D. M. Ciufo, E. A. O'Neill, T. J. Kelly, and G. S. Hayward. 1989. Overlapping octamer and TAATGARAT motifs in the VF65-response elements in herpes simplex virus immediate-early promoters represent independent binding sites for cellular nuclear factor III. J. Virol. 63:2798-2812.
2. Carbon, P., S. Murgo, J. P. Ebel, A. Krol, G. Tebb, and I. W. Mattaj. 1987 A common octamer binding protein is involved in the transcription of the U6 snRNA by polymerase III and U2 snRNA by RNA polymerase II. Cell 51:71-79.
3. Carpenter, D. E., and V. Misra. 1992. Sequences of the bovine herpesvirus 1 homologue of herpes simplex virus α-trans-inducing factor (UL48). Gene 119:259-263.
4. Cheung, C. H., Q. N. Fan, and W. E. Stumph. 1993. Structural requirements for the functional activity of a U1 snRNA gene enhancer. Nucleic Acids Res. 21:281-287.
5. Cleary, M. A., and W. Herr. 1995. Mechanisms for flexibility in DNA sequence recognition and VP16-induced complex formation by the Oct-1 POU domain. Mol. Cell. Biol. 15:2090-2100.
6. Dailey, L., H. B. Yuan, and C. Basilico. 1994. Interaction between a novel f9-specific factor and octamer-binding proteins is required for cell-type-restricted activity of the fibroblast growth factor 4 enhancer. Mol. Cell. Biol. 14:7758-7769.
7. Davison, A. J., and J. E. Scott. 1986. The complete DNA sequence of varicella-zoster virus. J. Gen. Virol. 67:1759-1816.
8. Elliott, G., and P. Ohare. 1995. Equine herpesvirus 1 gene 12, the functional homologue of herpes simplex virus VP16, transactivates via octamer sequences in the equine herpesvirus ie gene promoter. Virology 213:258-262.
9. Falkner, F. G., and H. G. Zachau. 1984. Correct transcription of an immunoglobulin κ gene requires an upstream fragment containing conserved sequence elements. Nature (London) 310:71-74.
10. Gerster, T., and R. G. Roeder. 1988. A herpesvirus trans-activating protein interacts with transcription factor OTF-1 and other cellular proteins. Proc. Natl. Acad. Sci. USA 85:6347-6351.
11. Greaves, R. F., and P. O'Hare. 1989. Separation of requirements for protein-DNA complex assembly from those for functional activity in the herpes simplex virus regulatory protein Vmw65. J. Virol. 63:1641-1650.
12. Greaves, R. F., and P. O'Hare. 1990. Structural requirements in the herpes simplex virus type 1 transactivator Vmw 65 for interaction with the cellular octamer-binding protein and target TAATGARAT sequences. J. Virol. 64: 2716-2724.
13. Groenen, M. A. M., R. J. M. Dijkhof, J. J. van der Poel, R. van Diggelen, and E. Verstege. 1992. Multiple octamer binding sites in the promoter region of the bovine alpha s2-casein gene. Nucleic Acids Res. 20:4311-4318.
14. Gstaiger, M., L. Knoepfel, O. Georgiev, W. Schaffner, and C. M. Hovens. 1995. A B-cell coactivator of octamer-binding transcription factors. Nature (London) 373:360-362.
15. Herr, W., R. A. Strum, R. G. Clerc, L. M. Corcoran, D. Baltimore, P. A. Sharpe, H. A. Ingraham, M. G. Rosenfeld, M. Finney, G. Ruvken, and H. R. Horvitz. 1988. The POU domain: a large conserved region in the mammalian pit- 1, Oct-1, Oct-2 and Caenorhabditis elegans unc-86 gene products. Genes Dev. 2:1513-1516.
16. Hill, C. S., J. Wynne, and R. Triesman. 1994. Serum regulated transcription by serum response factor (SRF): a novel role for the DNA binding domain. EMBO J. 13:5421-5432.
17. Katan, M., A. Haigh, C. P. Verrijzer, P. C. van der Vliet, and P. O'Hare. 1990. Characterization of a cellular factor which interacts functionally with Oct-I in the assembly of a multiprotein transcription complex. Nucleic Acids Res. 18:6871-6880.
18. Kaushansky, K., S. G. Shoemaker, C. A. Orork, and J. M. Mccarty. 1994 Coordinate regulation of multiple human lymphokine genes by Oct-1 and potentially novel 45 and 43 kda polypeptides. J. Immunol. 152:1812-1820.
19. Kristie, T. M., J. H. LeBowitz, and P. A. Sharp. 1989. The octamer binding proteins form multi-protein-DNA complexes with the HSV alpha TIF regulatory protein. EMBO J. 8:4229-4238.
20. Kristie, T. M., and B. Roizman. 1987. Host cell proteins bind to the cis-acting site required for virion-mediated induction of herpes simplex virus a genes. Proc. Natl. Acad. Sci. USA 84:71-75.
21. LaBella, F., H. L. Sive, R. G. Roeder, and N. Heintz. 1988. Cell cycle regulation of a histone 2b gene is mediated by the H2b subtype-specific concensus element. Genes Dev. 2:32-39.
22. Lefstin, J. A., J. R. Thomas, and K. R. Yamamoto. 1994. Influence of a steroid receptor DNA-binding domain on transcriptional regulatory functions. Genes Dev. 8:2842-2856.
23. Lewis, J. B., Y. G. Thompson, and G. Caughman. 1993. Transcriptional control of the equine herpesvirus 1 immediate early gene. Virology 197:788-792.
24. Luo, Y., and R. G. Roeder. 1995. Cloning, functional characterization, and mechanism of action of the B-cell-specific transcriptional coactivator OCA-B. Mol. Cell. Biol. 15:4115-4124.
25. Marsden, H. S., L. Campbell, L. Haarr, M. C. Frame, D. S. Parris, M. Murphy, R. G. Hope, M. T. Muller, and C. M. Preston. 1987. The 65,000-Mr DNA-binding and trans-inducing proteins of herpes simplex virus type 1. J. Virol. 61:2428-2437.
26. Mason, J. O., G. T. Williams, and M. S. Neuberger. 1985. Transcription cell-type specificity is conferred by an immunoglobulin Vh gene promoter that includes a functional consensus sequence. Cell 41:479-487.
27. McKee, T. A., G. H. Disney, R. D. Everett, and C. M. Preston. 1990. Control of expression of the varicella-zoster virus major immediate early gene. J. Gen. Virol. 71:897-906.
28. McKnight, J. L., T. M. Kristie, and B. Roizman. 1987. Binding of the virion protein mediating alpha gene induction in herpes simplex virus 1 infected cells to its cis site requires cellular proteins. Proc. Natl. Acad. Sci. USA 84:7061-7065.
29. Meyer, K. B., and M. S. Neuberger. 1989. The immunoglobulin κ chain locus contained a second, stronger B-cell specific enhancer which is located downstream of the constant region. EMBO J. 8:1959-1964.
30. Misra, V., A. C. Bratanich, D. Carpenter, and P. O'Hare. 1994. Protein and DNA elements involved in transactivation of the promoter of the bovine herpesvirus (BHV) 1 IE-1 transcription unit by the BHV a gene trans-inducing factor. J. Virol. 68:4898-4909.
31. Misra, V., S. Walker, S. Hayes, and P. O'Hare. 1995. The bovine herpesvirus a gene trans-inducing factor activates transcription by mechanisms that are different from those of its herpes simplex virus type 1 counterpart VP16. J. Virol. 69:5209-5216.
32. Mizushima-Sugano, J., and R. G. Roeder. 1986. Cell-type specific transcription of an immunoglobulin κ chain gene in vitro. Proc. Natl. Acad. Sci. USA 83:8511-8515.
33. O'Hare, P. 1993. The virion transactivator of herpes simplex virus. Semin. Virol. 4:145-155.
34. O'Hare, P., and C. R. Goding. 1988. Herpes simplex virus regulatory elements and the immunoglobulin octamer domain bind a common factor and are both targets for virion transactivation. Cell 52:435-445.
35. O'Hare, P., C. R. Goding, and A. Haigh. 1988. Direct combinatorial interaction between a herpes simplex virus regulatory protein and a cellular octamer-binding factor mediates specific induction of virus immediate-early gene expression. EMBO J. 7:4231-4238.
36. O'Rourke, D., and P. O'Hare. 1993. Mutually exclusive binding of two cellular factors within a critical promoter region of the gene for the IE110k protein of herpes simplex virus. J. Virol. 67:7201-7214.
37. Preston, C. M., M. C. Frame, and M. E. Campbell. 1988. A complex formed between cell components and a HSV structural polypeptide hinds to a viral immediate early gene regulatory DNA sequence. Cell 52:425-434.
38. Purewal, A. S., R. Allsopp, M. Riggio, E. A. R. Telford, S. Azam, A. J. Davison, and N. Edington. 1994. Equid herpesvirus 1 and 4 encode functional homologues of the herpes simplex virus type 1 virion transactivator protein, VP16. Virology 198:385-389.
39. Purewal, A. S., A. V. Smallwood, A. Kaushal, D. Adegboye, and N. Edington. 1992. Identification and control of the cis-acting elements of the immediate early gene of equid herpesvirus type 1. J. Gen. Virol. 73:513-519.
40. Ruvkun, G., and M. Finey. 1991. Regulation of transcription and cell identity by POU domain proteins. Cell 64:475-476.
41. Schier, A. F., and W. J. Gehring. 1993. Functional specificity of the homeodomain protein fuschi tarazu: the role of DNA binding specificity in vivo. Proc. Natl. Acad. Sci. USA 90:1450-1454.
42. Stern, S., M. Tanaka, and W. Herr. 1989. The Oct-1 homeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16. Nature (London) 341:624-630.
43. Strubin, M., J. W. Newell, and P. Matthias. 1995. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer binding proteins. Cell 80:497-506.
44. Tullius, T. D. 1989. Physical studies of protein-DNA complexes by footprinting. Annu. Rev. Biophys. Biophys. Chem. 18:213-237.
45. Tullius, T. D., B. A. Dombrowski, M. E. Churchill, and L. Kam. 1987. Hydroxyl radical footprinting: a high resolution method for mapping protein-DNA contacts. Methods Enzymol. 155:537-558.
46. Ullman, K. S., W. M. Flanagan, C. A. Edwards, and G. R. Crabtree. 1991. Activation of early gene expression in T lymphocytes by Oct-1 and an inducible protein OAP40. Science 254:558-562.
47. Verrijzer, C. P., and P. C. van der Vliet. 1993. POU domain transcription factors. Biochim. Biophys. Acta 1173:1-21.
48. Walker, S., S. Hayes, and P. Ohare. 1994. Site-specific conformational alteration of the Oct-1 POU domain-DNA complex as the basis for differential recognition by Vmw65 (VP16). Cell 79:841-852.
49. Wegner, M., D. W. Drolet, and M. G. Rosenfeld. 1993. POU-domain proteins: structure and function of developmental regulators. Curr. Opin. Cell Biol. 5:488-498.
50. Wilson, A. C., K. LaMarco, M. G. Peterson, and W. Herr. 1993. The VP16 accessory protein HCF is a family of polypeptides processed from a large precursor protein. Cell 74:115-125.
51. Wu, C. 1984. Two protein-binding sites in chromatin implicated in the activation of heat shock genes. Nature (London) 309:229-334.
52. Xiao, P., and J. P. Capone. 1990. A cellular factor binds to the herpes simplex virus transactivator Vmw65 and is required for Vmw65-dependent protein-DNA complex assembly with Oct-1. Mol. Cell. Biol. 10:4974-4977.
53. Zhou, D.-X., and T. S. B. Yen. 1991. The ubiquitous transcription factor Oct-1 and the liver-specific factor HNF-1 are both required to activate transcription of a hepatitis B virus promoter. Mol. Cell. Biol. 11:1353-1359.