Prostaglandin E2 as a modulator of lymphocyte mediated inflammatory and humoral responses

Advances in Experimental Medicine and Biology

Volumn 469, Issue , 2000, Pages 409-412

  Kaur, K ^a   Harris, S G ^a   Padilla, J ^a   Graf, B A ^a   Phipps, R P ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTAGLANDIN E2;

ANIMAL CELL; ANTIGEN PRESENTING CELL; CELL DIFFERENTIATION; CELL MEDIATED CYTOTOXICITY; CONFERENCE PAPER; CYTOKINE RELEASE; HUMORAL IMMUNITY; IMMUNE RESPONSE; INFLAMMATORY CELL; LYMPHOCYTOPOIESIS; NONHUMAN; PRIORITY JOURNAL; SECOND MESSENGER; STIMULUS RESPONSE; T LYMPHOCYTE ACTIVATION;

ANIMALS; B-LYMPHOCYTES; CYTOKINES; DINOPROSTONE; HUMANS; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LYMPHOCYTES; TH1 CELLS; TH2 CELLS;

ANIMALIA;

EID: 0034464092     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (15)

1. Prostaglandin E2 inhibits B lymphocyte activation by a cAMP-dependent mechanism: PGE-inducible regulatory proteins
2. Prostanoid receptors and their biological actions
3. A molecular analysis of PGE receptor (EP) expression on normal and transformed B lymphocytes: Coexpression of EP1, EP2, EP3beta and EP4
4. Prostaglandin E2 receptors of the EP2 and EP4 subtypes regulate activation and differentiation of mouse B lymphocytes to IgE-secreting cells
5. Prostaglandin E2 promotes B lymphocyte Ig isotype switching to IgE
6. Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell-type CD4+ T cell response
7. In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1-
8. Low-level infection with Trichuris muris significantly affects the polarization of the CD4 response
9. Role of cytokines in development of Th1 and Th2 cells
10. Prostaglandin E2 inhibits production of Th1 lymphokines but not of Th2 lymphokines
11. Prostaglandin E2 differentially modulates cytokine secretion profiles of human T helper lymphocytes
12. Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production
13. Interleukin-10 is associated with the development of sepsis in trauma patients
14. Association of interleukin-4 plasma levels with traumatic injury and clinical course
15. Increased plasma IgE levels in patients with sepsis after traumatic injury