The effects of 5-AZA-2′-deoxycytidine (D-AZA) on sonic hedgehog expression in mouse embryonic limb buds

Toxic Substance Mechanisms

Volumn 19, Issue 2, 2000, Pages 125-133

  Branch, S ^a   Smoak, I W ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; COMPLEMENTARY DNA; COMPLEMENTARY RNA; CYCLOPHILIN; SONIC HEDGEHOG PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EMBRYO; FEMALE; GENE CONTROL; GENE EXPRESSION; GENE INDUCTION; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LIMB DEVELOPMENT; MOUSE; NONHUMAN; PHOCOMELIA; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; SIGNAL TRANSDUCTION;

ANIMALIA; ERINACEIDAE; RODENTIA;

EID: 0034460103     PISSN: 10769188     EISSN: None     Source Type: Journal    
DOI: 10.1080/10769180052008904     Document Type: Article

References (20)

1. Cloning of a mouse smoothened cDNA and expression patterns of hedgehog signalling molecules during chondrogenesis and cartilage differentiation in clonal mouse EC cells, ATDC5
2. Downstream of the homeotic genes
3. Teratogenic effects of the demethylating agent 5-aza-2′-deoxycytidine in the Swiss Webster mouse
4. Differentially expressed genes associated with 5-aza-2′-deoxycytidine-induced hindlimb defects in the Swiss Webster mouse
5. Evidence for genetic control of Sonic Hedgehog by Gli3 in mouse limb development
6. Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
7. Detection of cytokine transcriptional profiles from bovine peripheral blood mononuclear cells and CD4+ lymphocytes by reverse transcriptase polymerase chain reaction
8. Evaluation of biotinylated oligonucleotide probes for in situ hybridization
9. Signalling by hedgehog family proteins in Drosophila and vertebrate development
10. Post-natal development of gonotropin-releasing hormone and cyclophilin gene expression in the female and male rat brain
11. Sonic hedgehog: A key mediator of anterior-posterior patterning of the limb and dorso-ventral patterning of axial embryonic structures
12. Sonic hedgehog and Fgf-4 act through a signalling cascade and feedback loop to integrate growth and patterning of the developing limb bud
13. Why thumbs are up
14. Induction of osteogenic differentiation by hedgehog proteins
15. Fgf-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb
16. Sonic hedgehog mediates the polarizing activity of the ZPA
17. A reverse transcription-polymerase chain reaction technique to detect feline cytokine genes
18. Hox genes, arms and man
19. Vertebrate limb development
20. Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein