Prolonged treatment with recombinant insulin-like growth factor-I in children with growth hormone insensitivity syndrome - A clinical research center study

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 9, 1996, Pages 3312-3317

  Backeljauw, Philippe F ^a,b   Underwood, Louis E ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b CAROLINAS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECOMBINANT SOMATOMEDIN C;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BODY HEIGHT; BONE AGE; CHILD; CLINICAL ARTICLE; CLINICAL RESEARCH; DRUG EFFECT; FEMALE; GENE DELETION; GROWTH HORMONE DEFICIENCY; HORMONE RESISTANCE; HUMAN; HYPOGLYCEMIA; LARON SYNDROME; MALE; PRIORITY JOURNAL;

AGE DETERMINATION BY SKELETON; AGING; AUTOANTIBODIES; BODY COMPOSITION; CHILD; CHILD, PRESCHOOL; FEMALE; GROWTH DISORDERS; GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; KIDNEY; MALE; RECEPTORS, SOMATOTROPIN; RECOMBINANT PROTEINS; SPLEEN; WEIGHT GAIN;

EID: 19244363865     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.9.3312     Document Type: Article

References (10)

1. Laron Z, Blum W, Chatelain P, et al. 1993 Classification of growth hormone insensitivity syndrome. J Pediatr. 122:241.
2. Rosenfeld RG, Rosenbloom AL, Guevara-Aguirre J. 1994 Growth hormone insensitivity due to primary GH receptor deficiency. Endocr Rev. 15:369-390.
3. Anselem S, Duquesnoy P, Durien B, et al. 1993 Spectrum of growth hormone receptor mutations and associated haplotypes in Laron syndrome. Hum Mol Genet. 4:355-359.
4. Berg MA, Argente J, Chernausek S, et al. 1993 Diverse growth hormone receptor gene mutations in Laron syndrome. Am J Hum Genet. 52:998-1005.
5. Laron Z, Klinger B. 1994 Laron syndrome: clinical features, molecular pathology and treatment. Horm Res. 42:198-202.
6. Savage MO, Chatelain PG, Preece MA, Ranke MB, Sietnieks A, Wilton P. 1991 Clinical spectrum of the syndrome on growth hormone insensitivity. Acta Paediatr Scand. 377(Suppl):87-90.
7. Elders JM, Garland JT, Daughaday WH, Fisher DA, Whitney JE, Hughes ER. 1973 Laron dwarfism: studies on the nature of the defect. J Pediatr. 83:253-263.
8. Van Wyk JJ. 1984 The somatomedins: biological actions and physiological control mechanisms. In: Li CH, ed. Hormonal proteins and peptides. Orlando: Academic Press; vol 12:81-125.
9. Walker JL, Ginalska-Malinowska M, Romer TE, Pucilowska JB, Underwood LE. 1991 Effects of the infusion of insulin-like growth factor I in a child with growth hormone insensitivity syndrome (Laron dwarfism). N Engl J Med. 324:1483-1488.
10. Walker JL, Van Wyk JJ, Underwood LE. 1992 Stimulation of stalural growth by recombinant insulin-like growth factor I in a child with growth hormone insensitivity syndrome. J Pediatr. 121:641-646.