A case of LGMD2A identified with both Western blot analysis and immunostaining of calpain 3 in biopsied muscle

Clinical Neurology

Volumn 40, Issue 10, 2000, Pages 1023-1027

  Ibi, T ^a   Jing, L ^a   Nakao, N ^a   Minami, N ^a   Sahashi, K ^a  

^a AICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Calpain 3; Immunostaining; Limb girdle form; Muscular dystrophy; Wertern blot analysis

Indexed keywords

CALPAIN; CALPAIN 3; CREATINE KINASE; LEUCINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CALPAIN 3; NCL CALP 2 C 4; UNCLASSIFIED DRUG; VALINE;

ADULT; ARTICLE; CASE REPORT; CLINICAL FEATURE; DIAGNOSTIC PROCEDURE; DISEASE COURSE; FEMALE; GENETIC ANALYSIS; HUMAN; IMMUNOHISTOCHEMISTRY; LIMB GIRDLE MUSCULAR DYSTROPHY; MUSCLE ATROPHY; MUSCLE BIOPSY; MUSCLE WEAKNESS; WESTERN BLOTTING;

BIOLOGICAL MARKERS; BLOTTING, WESTERN; CALPAIN; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MIDDLE AGED; MUSCLE PROTEINS; MUSCLE, SKELETAL; MUSCULAR DYSTROPHIES; MUTATION;

EID: 0034457048     PISSN: 0009918X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Mutations in the proteolytic enzyme calpain 3 cause limb-girdle muscular dystrophy type 2A
2. Calpainopathy - A survey of mutations and polymorphisms
3. Characterization of monoclonal antibodies to calpain 3 and protein expression in muscle from patients with limb-girdle muscular dystrophy type 2A
4. Functional defects of a muscle-specific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2A
5. Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connection through IS2 a p 94 specific sequence