5-thio-D-glucose elevates renal transforming growth factor β-1 at a dose that does not prevent streptozocin diabetes in rats

Endocrinology

Volumn 141, Issue 9, 2000, Pages 3337-3342

  Lane, Pascale H ^a,b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THIOGLUCOSE; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIABETIC NEPHROPATHY; HISTOPATHOLOGY; HORMONE DETERMINATION; IMMUNOHISTOCHEMISTRY; KIDNEY HYPERTROPHY; MALE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ASSAY; RAT; RNA ANALYSIS; STREPTOZOCIN DIABETES;

EID: 0034456390     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.141.9.7676     Document Type: Article

References (17)

1. Studies on the ability of compounds to block the diabetogenic activity of streptozotocin
2. Studies on streptozotocin diabetes
3. Prevention of high- and low-dose STZ-induced diabetes with D-glucose and 5-thio-D-glucose
4. GLUT2 in pancreatic islets: Crucial target molecule in diabetes induced with multiple low doses of streptozotocin in mice
5. Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-β as a key mediator
6. Acquiring images
7. Segmentation and thresholding
8. Estimation of glomerular volume: A comparison of four methods
9. cDNA cloning and sequence analysis of βig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-β
10. Renal expression of transforming growth factor-β inducible gene-h3 (βig-h3) in normal and diabetic rats
11. 5-thio-D-glucose causes increased feeding and hyperglycemia in the rat
12. Glucose concentration and insulin release in 5-thio-D-glucose treated mice
13. Longer-term fourth ventricular 5-thioglucose infusion increases body fat in the rat
14. Age of onset of streptozocin diabetes determines the renal structural response in the rat
15. Effect of puberty on initial kidney growth and rise in kidney IGF-I in diabetic rats
16. Diminished glomerular capillary, hydraulic conductivity precedes morphologic changes in experimental diabetes mellitus in the rat
17. Improved sandwich enzyme-linked immunosorbent assays for transforming growth factor β1