Longer-term fourth ventricular 5-thioglucose infusion increases body fat in the rat

Proceedings of the Society for Experimental Biology and Medicine

Volumn 217, Issue 2, 1998, Pages 168-172

  He, Bin ^a   White, B Douglas ^a   Edwards, Gaylen L ^b   Martin, Roy J ^a,b  

^a UNIVERSITY OF GEORGIA   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THIOGLUCOSE;

ANIMAL EXPERIMENT; ARTICLE; BODY FAT; CONTROLLED STUDY; ENERGY BALANCE; FEMALE; FOOD INTAKE; GLUCOSE HOMEOSTASIS; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; LIPID STORAGE; NEUROMODULATION; NONHUMAN; RAT;

EID: 0031893438     PISSN: 00379727     EISSN: None     Source Type: Journal    
DOI: 10.3181/00379727-217-44219     Document Type: Article

References (35)

1. Houpt TR, Hance HE. Stimulation of food intake in the rabbit and rat by inhibition of glucose metabolism with 2-deoxy-D-glucose. J Comp Physiol 76:395-100, 1971.
2. Houpt TR. Stimulation of food intake in ruminants by 2-deoxy-D-glucose and insulin. Am J Physiol 227:161-167, 1974.
3. Smith GP, Epstein AN. Increased feeding in response to decreased glucose utilization in the rat and monkey. Am J Physiol 217:1083-1087, 1969.
4. Ritter RC, Slusser P. 5-Thio-D-glucose causes increased feeding and hypergiycemia in the rat. Am J Physiol 238:E141-144, 1980.
5. Oomura Y. Significance of glucose, insulin and free fatty acids on the hypothalamic feeding and satiety neurons. In: Novin D, Wynvicka W, Bray G, Eds. Hunger: Basic Mechanisms and Clinical Implications. New York: Raven Press, p145, 1976.
6. Oomura Y. Neural network of glucose monitoring system. J Autonom Nerv Syst 10:159-170, 1984.
7. Bird E, Cardone CC, Contreras RJ. Area postrema lesions disrupt food intake induced by cerebroventricular infusions of 5-thioglucose in the rat. Brain Res 270:193-196, 1983.
8. Ritter RC, Slusser PG, Stone S. Glucoreceptors controlling feeding and blood glucose: Location in hindbrain. Science 213:451-453, 1981.
9. Shiraishi T, Mager M. Hypothermia following injection of 2-deoxy-D-glucose into selected hypothalamic sites. Am J Physiol 239:R265-269, 1980.
10. Arase K, York DA, Bray GA. Corticosterone inhibition of the intracerebroventricular effect of 2-deoxy-D-glucose on brown adipose tissue thermogenesis. Physiol Behav 40:489-495, 1987.
11. Akabayashi A, Zaia CTBV, Silva I, Chae HJ, Leibowitz SF. Neuropeptide Y in the arcuate nucleus is modulated by alterations in glucose utilization. Brain Res 621:343-348, 1993.
12. Clark JT, Kalra PS, Crowley WR, Kalra SP. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 115:427-429, 1984.
13. Stanley BG, Leibowitz SF. Neuropeptide Y injected in the paraventricular hypothalamus: A powerful stimulant of feeding behavior. Proc Natl Acad Sci USA 82:3940-3943, 1985.
14. Steinmann JL, Gunion MW, Morley JE. Third and fourth ventricle neuropeptide Y (NPY) stimulates feeding and drinking in rats. Fed Proc 46:1125-1130, 1987.
15. Stanley BG, Kyrkouli SE, Lampert S, Leibowitz SF. Neuropeptide Y chronically injected into the hypothalamus: A powerful neurochemical inducer of hyperphagia and obesity. Peptides 7:1189-1192, 1986.
16. Estaban J, Chover AJ, Sanchez PA, Mico JA, Gibert-Rahola J. Central administration of neuropeptide Y induces hypothermia in mice. Possible interaction with central noradrenergic systems. Life Sci 45:2395-2400, 1989.
17. Roscoe AK, Myers RD. Hypothermia and feeding induced simultaneously in rats by perfusion of neuropeptide Y in preoptic area. Pharmacol Biochem Behav 39:1003-1009, 1991.
18. Billington CJ, Briggs JE, Grace M, Levine AS. Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism. Am J Physiol 260:R321-327, 1991.
19. Billington CJ, Briggs JE, Harker S, Grace M, Levine AS. Neuropeptide Y in hypothalamic paraventricular nucleus: A center coordinating energy metabolism. Am J Physiol 266:R1765-1770, 1994.
20. Egawa M, Yoshimatsu H, Bray GA. Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats. Am J Physiol 260:R328-334, 1991.
21. Stanley BG. Neuropeptide Y in multiple hypothalamic sites controls eating behavior, endocrine, and autonomic systems for body energy balance. In: Colmers WF, Wahlestedt C, Eds. The Biology of Neuropeptide Y and Related Peptides. Ottawa: The Humana Press Inc., p457, 1993.
22. Zhang YY, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homolog. Nature 372:425-432, 1994.
23. Pelleymounter MA, Cullen MJ, Baker MB, Hecht R, Winters D, Boone T, Collins F. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269:540-543, 1995.
24. Halaas JL, Gaiiwala KS, Maffei M, Cohen SL, Chait BT, Rabinowitz D, Lallone RL, Burley SK, Friedman JM. Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546, 1995.
25. Campfield LA, Smith FJ, Guisez Y, Devos R, Bum P. Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549, 1995.
26. Frederich RC, Lollmann B, Hamann A, Napolitano-Rosen A, Kahn BB, Lowell BB, Flier JS. Expression of ob mRNA and its encoded protein in rodents: Impact of nutrition and obesity. J Clin Invest 96:1658-1663, 1995.
27. Frederich RC, Hamann A, Anderson S, Lollmann B, Lowell BB, Flier JS. Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action. Nat Med 1:1311-1314, 1995.
28. Stephens TW, Basinski M, Bristow PK, Bue-Vaileskey JM, Burgett SG, Craft L, Hale J, Hoffman J, Hsiung HM, Kriauciunas A, MacKellar W, Rosteck PR Jr, Schoner B, Smith D, Tinsley FC, Zhang XY, Heiman M. The role of neuropeptide Y in the antiobesity action of the obese gene product. Nature 377:530-532, 1995.
29. Veeraragavan K, Ramakrishnan S. Glucose concentration and insulin release in 5-thio-D-glucose-treated mice. Metabolism 32:1115-1119, 1983.
30. Painson JC, Tannenbaum GS. Effects of intracellular glucopenia on pulsatile growth hormone secretion: Mediation in part by somatostatin. Endocrinology 117:1132-1138, 1985.
31. Penicaud L, Pajot MT, Thompson DA. Evidence that receptors controlling growth hormone and hyperglycemic responses to glucoprivation are located in the hindbrain. Endocr Res 16:461-475, 1990.
32. Antoni FA. Hypothalamic control of adrenocorticotropin secretion: Advances since the discovery of 41-residue corticotropin-releasing factor. Endocrine Rev 7:351-378, 1986.
33. Britton D, Koob G, Rivier J, Vale W. Intraventricular corticotropin-releasing factor enhances behavioral effects of novelty. Life Sci 31:363-367, 1982.
34. Morley JE, Levine AS. Corticotropin releasing factor, grooming and ingestive behaviors. Life Sci 31:1459-1464, 1982.
35. Weidenfeld J, Corcos AP, Wohlman A, Feldman S. Characterization of the 2-deoxyglucose effect on the adrenocortical axis. Endocrinology 134:1924-1931, 1994.