Different effects of GABAergic anticonvulsants on 4-aminopyridine-induced spontaneous GABAergic hyperpolarizations of hippocampal pyramidal cells - Implication for their potency in migraine therapy

Cephalalgia

Volumn 20, Issue 6, 2000, Pages 533-537

  Leniger, T ^a   Wiemann, M ^a   Bingmann, D ^a   Hufnagel, A ^a   Bonnet, U ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Excitability; GABA; Gabapentin; Migraine; Tiagabine; Valproate; Vigabatrin

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; 2 HYDROXYSACLOFEN; 4 AMINOBUTYRATE AMINOTRANSFERASE; 4 AMINOPYRIDINE; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ANTICONVULSIVE AGENT; BICUCULLINE METHIODIDE; GABAPENTIN; GLUTAMATE DECARBOXYLASE; SUCCINATE SEMIALDEHYDE DEHYDROGENASE; TIAGABINE; VALPROIC ACID; VIGABATRIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; GABAERGIC SYSTEM; GUINEA PIG; HIPPOCAMPUS; HYPERPOLARIZATION; NEUROMODULATION; NONHUMAN; PYRAMIDAL NERVE CELL;

4-AMINOPYRIDINE; ACETIC ACIDS; AMINES; ANALGESICS; ANIMALS; ANTICONVULSANTS; CONVULSANTS; CYCLOHEXANECARBOXYLIC ACIDS; GABA AGONISTS; GAMMA-AMINOBUTYRIC ACID; GUINEA PIGS; HIPPOCAMPUS; HUMANS; MEMBRANE POTENTIALS; MIGRAINE DISORDERS; NIPECOTIC ACIDS; PYRAMIDAL CELLS; TIME FACTORS; VALPROIC ACID; VIGABATRIN;

EID: 0034453876     PISSN: 03331024     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1468-2982.2000.00080.x     Document Type: Article

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