Neopterin production and tryptophan degradation in humans infected by Streptococcus pyogenes

Medical Microbiology and Immunology

Volumn 189, Issue 3, 2001, Pages 161-163

  Murr, Christian ^a   Gerlach, Dieter ^b   Widner, Bernhard ^a   Dierich, Manfred P ^a,c   Fuchs, Dietmar ^a,c  

^a UNIVERSITY OF INNSBRUCK   (Austria)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^c LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

Author keywords

Neopterin; Streptococcus pyogenes; Tryptophan degradation

Indexed keywords

EXOTOXIN; KYNURENINE; NEOPTERIN; TRYPTOPHAN;

ARTICLE; DISEASE SEVERITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SYNTHESIS; STREPTOCOCCUS PYOGENES; T LYMPHOCYTE ACTIVATION; TONSILLITIS; TOXIC SHOCK SYNDROME;

EID: 0034451873     PISSN: 03008584     EISSN: None     Source Type: Journal    
DOI: 10.1007/s430-001-8023-3     Document Type: Article

References (16)

1. Inducible anti-parasitic effector mechanisms in human uroepithelial cells: Tryptophan degradation vs NO production
2. Value of urinary neopterin in the differential diagnosis of bacterial and viral infections
3. Decreased serum tryptophan in patients with HIV-1 infection correlates with increased serum neopterin and neurologic/psychiatric symptoms
4. The role of neopterin as a monitor of cellular immune activation in transplantation, inflammatory, infectious and malignant diseases
5. Superantigens in human disease
6. Epidemiologie und pathogenese von streptokokkeninfektionen
7. Tryptophan catabolism and T-cell tolerance: Immunosuppression by starvation?
8. Comparative study of cytokine release by human peripheral blood mononuclear cells with Streptococcus pyogenes superantigenic toxins, heat-killed streptococci, and lipopolysaccharide
9. Inhibition of T cell proliferation by macrophage tryptophan catabolism
10. Streptococcal erythrogenic toxins induce the formation of neopterin in human peripheral blood mononuclear cells but not in the human myelomonocytoma cell line THP-1
11. Streptococcal erythrogenic toxins induce tryptophan degradation in human peripheral blood mononuclear cells
12. Flesh-eating bacteria: Not new, but still worrisome
13. Interferon γ blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan
14. Severe group A streptococcal infections associated with a toxic shock-like syndrome and scarlet fever toxin A
15. Parallel induction of tetrahydrobiopterin biosynthesis and indoleamine 2,3-dioxygenase activity in human cells and cell lines by interferon-γ
16. Simultaneous determination of serum tryptophan and kynurenine by HPLC