Chitotriosidase as a new marker of macrophage stimulation in a tumor model treated with cyclophosphamide and Ukrain

Drugs under Experimental and Clinical Research

Volumn 26, Issue 5-6, 2000, Pages 279-283

  Korolenko, T A ^a   Djanayeva, S J ^a   Falameyeva, O V ^a   Wevers, R A ^a   Filjushina, E E ^a   Buzueva, I I ^a   Kaledin, V I ^a   Sandula, J ^a   Nowicky, J ^a  

^a INSTITUTE OF PHYSIOLOGY   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; CHITINASE; CHITOTRIOSIDASE; CYCLOPHOSPHAMIDE; GLUCAN; TYLOXAPOL; UKRAIN; UNCLASSIFIED DRUG; ZYMOSAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; ENZYME ACTIVITY; IMMUNOSTIMULATION; LYMPHOSARCOMA; MACROPHAGE ACTIVATION; MALE; MOUSE; NONHUMAN; RAT; TUMOR GROWTH; TUMOR MODEL;

ALKALOIDS; ANIMALS; ANTINEOPLASTIC AGENTS, ALKYLATING; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BERBERINE ALKALOIDS; CYCLOPHOSPHAMIDE; HEXOSAMINIDASES; LIVER; LYMPHOMA, DIFFUSE; MACROPHAGES; MALE; MICE; MICE, INBRED CBA; NEOPLASMS, EXPERIMENTAL; PHENANTHRIDINES; TUMOR MARKERS, BIOLOGICAL;

EID: 0034449754     PISSN: 03786501     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Macrophage stimulation and antitumor effect of Ukrain
2. Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins
3. Synthesis, sorting, and processing into distinct isoforms of human macrophage chitotriosidase
4. Chitotriosidase, a chitinase, and the 39-kDa human cartilage glyco-protien, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages
5. Serum chitotriosidase activity in Gaucher patients on enzyme replacement therapy (ERT)
6. Marked elevation of plasma chitotriosidase activity. A novel hallmark of Gaucher disease
7. Elevated plasma chitotriosidase activity in various lysosomal storage discorder
8. Potentiation of non-specific host defence by polysaccharides like lentinan: Possible mechanisms
9. Cyclophosphane-induced apoptosis of murine lymphosarcoma cells: Experimental model in vivo
10. Strong induction of members of the chitinase family of proteins in atherosclerosis: Chitotriosidase and human cartilage gp-39 expressed in lesion macrophages