메뉴 건너뛰기




Volumn 17, Issue 7-9, 2000, Pages 597-605

'Heparin' - From anticoagulant drug into the new biology

Author keywords

Antithrombin; Growth factors; Heparan sulfate; Heparin; Iduronic acid; Sulfotransferases

Indexed keywords

ANTICOAGULANT AGENT; HEPARAN SULFATE; HEPARIN;

EID: 0034444008     PISSN: 02820080     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1011030711317     Document Type: Review
Times cited : (64)

References (85)
  • 1
    • 0022384993 scopus 로고
    • Molecular distinctions between heparan sulphate and heparin. Analysis of sulphation patterns indicates that heparan sulphate and heparin are separate families of N-sulphated polysaccharides
    • 1 Gallagher JT, Walker A, Molecular distinctions between heparan sulphate and heparin. Analysis of sulphation patterns indicates that heparan sulphate and heparin are separate families of N-sulphated polysaccharides, Biochem J 230, 665-74 (1985).
    • (1985) Biochem J , vol.230 , pp. 665-674
    • Gallagher, J.T.1    Walker, A.2
  • 4
    • 0014030865 scopus 로고
    • Further characterization of the heparin-protein linkage region
    • 4 Lindahl U, Further characterization of the heparin-protein linkage region, Biochim Biophys Acta 130, 368-82 (1966).
    • (1966) Biochim Biophys Acta , vol.130 , pp. 368-382
    • Lindahl, U.1
  • 5
    • 0015216938 scopus 로고
    • Identification of iduronic acid as the major sulfated uronic acid of heparin
    • 5 Lindahl U, Axelsson O, Identification of iduronic acid as the major sulfated uronic acid of heparin, J Biol Chem 246, 74-82 (1970).
    • (1970) J Biol Chem , vol.246 , pp. 74-82
    • Lindahl, U.1    Axelsson, O.2
  • 6
    • 0001582868 scopus 로고
    • A proton magnetic resonance spectral study of heparin, L-iduronic acid residues in commercial heparins
    • 6 Perlin AS, Mazurek M, Jaques LB, Kavanagh LW, A proton magnetic resonance spectral study of heparin, L-iduronic acid residues in commercial heparins, Carbohyd Res 7, 369-79 (1968).
    • (1968) Carbohyd Res , vol.7 , pp. 369-379
    • Perlin, A.S.1    Mazurek, M.2    Jaques, L.B.3    Kavanagh, L.W.4
  • 7
    • 0035707396 scopus 로고    scopus 로고
    • Structure and biological interactions of heparin and heparan sulfate
    • in press
    • 7 Casu B, Lindahl U, Structure and biological interactions of heparin and heparan sulfate. Adv Carbhohyd Chem Biochem (2000) in press.
    • (2000) Adv Carbhohyd Chem Biochem
    • Casu, B.1    Lindahl, U.2
  • 8
    • 0015218645 scopus 로고
    • Occurrence and biosynthesis of β-glucuronidic linkages in heparin
    • 8 Helting T, Lindahl U, Occurrence and biosynthesis of β-glucuronidic linkages in heparin, J Biol Chem 246, 5442-7 (1971).
    • (1971) J Biol Chem , vol.246 , pp. 5442-5447
    • Helting, T.1    Lindahl, U.2
  • 9
    • 0004961783 scopus 로고
    • Proton chemical-shift assignments in the n.m.r. Spectra of heparan and heparin
    • 9 Huckerby TN, Nieduszynski IA, Proton chemical-shift assignments in the n.m.r. spectra of heparan and heparin. Carbohyd Res 103, 141-5 (1982).
    • (1982) Carbohyd Res , vol.103 , pp. 141-145
    • Huckerby, T.N.1    Nieduszynski, I.A.2
  • 10
    • 0014217079 scopus 로고
    • Structure of dermatan sulfate II. Characterization of products obtained by hyaluronidase digestion of dermatan sulfate
    • 10 Fransson L-Å, Rodén L, Structure of dermatan sulfate II. Characterization of products obtained by hyaluronidase digestion of dermatan sulfate, J Biol Chem 242, 4170-5 (1967).
    • (1967) J Biol Chem , vol.242 , pp. 4170-4175
    • Fransson, L.-Å.1    Rodén, L.2
  • 11
    • 0001755234 scopus 로고
    • On heparin monosulfuric acid
    • 11 Jorpes JE, Gardell S, On heparin monosulfuric acid, J Biol Chem 176, 267-75 (1948).
    • (1948) J Biol Chem , vol.176 , pp. 267-275
    • Jorpes, J.E.1    Gardell, S.2
  • 12
    • 0000492518 scopus 로고
    • Reaction of heparitin sulfate with nitrous acid
    • 12 Cifonelli A, Reaction of heparitin sulfate with nitrous acid, Carbohyd Res 8, 233-42 (1968).
    • (1968) Carbohyd Res , vol.8 , pp. 233-242
    • Cifonelli, A.1
  • 13
    • 0004945887 scopus 로고
    • Variable content of 2-acetoamido-2-deoxy-D-glucose and neutral sugars in mammalian heparins
    • 13 Cifonelli JA, King J, Variable content of 2-acetoamido-2-deoxy-D-glucose and neutral sugars in mammalian heparins, Carbohyd Res 12, 391-402 (1970).
    • (1970) Carbohyd Res , vol.12 , pp. 391-402
    • Cifonelli, J.A.1    King, J.2
  • 14
    • 0015935891 scopus 로고
    • Biosynthesis of heparin. Formation of sulfamino groups
    • 14 Lindahl U, Bäckström G, Jansson L, Hallén A, Biosynthesis of heparin. Formation of sulfamino groups, J Biol Chem 248, 7234-41 (1973).
    • (1973) J Biol Chem , vol.248 , pp. 7234-7241
    • Lindahl, U.1    Bäckström, G.2    Jansson, L.3    Hallén, A.4
  • 15
    • 0017189425 scopus 로고
    • Formation of anhydrosugars in the chemical depolymerization of heparin
    • 15 Shively JE, Conrad HE, Formation of anhydrosugars in the chemical depolymerization of heparin, Biochemistry 15, 3932-42 (1976).
    • (1976) Biochemistry , vol.15 , pp. 3932-3942
    • Shively, J.E.1    Conrad, H.E.2
  • 16
    • 0020108082 scopus 로고
    • Further characterization of the antithrombin-binding sequence in heparin
    • 16 Thunberg L, Bäckström G, Lindahl U, Further characterization of the antithrombin-binding sequence in heparin, Carbohyd Res 100, 393-410 (1982).
    • (1982) Carbohyd Res , vol.100 , pp. 393-410
    • Thunberg, L.1    Bäckström, G.2    Lindahl, U.3
  • 17
    • 0024597524 scopus 로고
    • The disaccharide composition of heparins and heparan sulfates
    • 17 Guo Y, Conrad HE, The disaccharide composition of heparins and heparan sulfates, Anal Biochem 176, 96-104 (1989).
    • (1989) Anal Biochem , vol.176 , pp. 96-104
    • Guo, Y.1    Conrad, H.E.2
  • 19
    • 0030669701 scopus 로고    scopus 로고
    • Structure-activity relationship of heparan sulphate
    • 19 Gallagher JT, Structure-activity relationship of heparan sulphate, Biochem Soc Trans 25, 1206-9 (1997).
    • (1997) Biochem Soc Trans , vol.25 , pp. 1206-1209
    • Gallagher, J.T.1
  • 20
    • 0033603298 scopus 로고    scopus 로고
    • Highly sensitive sequencing of the sulfated domains of heparan sulfate
    • 20 Merry CL, Lyon M, Deakin JA, Hopwood JJ, Gallagher JT, Highly sensitive sequencing of the sulfated domains of heparan sulfate, J Biol Chem 274, 18455-62 (1999).
    • (1999) J Biol Chem , vol.274 , pp. 18455-18462
    • Merry, C.L.1    Lyon, M.2    Deakin, J.A.3    Hopwood, J.J.4    Gallagher, J.T.5
  • 21
    • 0032577484 scopus 로고    scopus 로고
    • Age-dependent modulation of heparan sulfate structure and function
    • 21 Feyzi E, Saldeen T, Larsson E, Lindahl U, Salmivirta M, Age-dependent modulation of heparan sulfate structure and function, J Biol Chem 273, 13395-8 (1998).
    • (1998) J Biol Chem , vol.273 , pp. 13395-13398
    • Feyzi, E.1    Saldeen, T.2    Larsson, E.3    Lindahl, U.4    Salmivirta, M.5
  • 22
    • 0028895640 scopus 로고
    • Structure of heparan sulphate from human brain, with special regard to Alzheimer's disease
    • 22 Lindahl B, Eriksson L, Lindahl U, Structure of heparan sulphate from human brain, with special regard to Alzheimer's disease, Biochem J 306, 177-84 (1995).
    • (1995) Biochem J , vol.306 , pp. 177-184
    • Lindahl, B.1    Eriksson, L.2    Lindahl, U.3
  • 23
    • 0030717480 scopus 로고    scopus 로고
    • Amyloid-specific heparan sulfate from human liver and spleen
    • 23 Lindahl B, Lindahl U, Amyloid-specific heparan sulfate from human liver and spleen, J Biol Chem 272, 26091-4 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 26091-26094
    • Lindahl, B.1    Lindahl, U.2
  • 24
    • 0034609536 scopus 로고    scopus 로고
    • Structural diversity of N-sulfated heparan sulfate domains
    • 24 Safaiyan F, Lindahl U, Salmivirta M, Structural diversity of N-sulfated heparan sulfate domains, Biochemistry 39, 10823-30 (2000).
    • (2000) Biochemistry , vol.39 , pp. 10823-10830
    • Safaiyan, F.1    Lindahl, U.2    Salmivirta, M.3
  • 26
    • 0032557443 scopus 로고    scopus 로고
    • Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney
    • 26 van Kuppevelt TH, Dennissen MA, van Venrooij WJ, Hoet RM, Veerkamp JH, Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney, J Biol Chem 273, 12960-6 (1998).
    • (1998) J Biol Chem , vol.273 , pp. 12960-12966
    • Van Kuppevelt, T.H.1    Dennissen, M.A.2    Van Venrooij, W.J.3    Hoet, R.M.4    Veerkamp, J.H.5
  • 28
    • 0032981696 scopus 로고    scopus 로고
    • A strategy for rapid sequencing of heparan sulfate and heparin saccharides
    • 28 Turnbull JE, Hopwood JJ, Gallagher JT, A strategy for rapid sequencing of heparan sulfate and heparin saccharides, Proc Natl Acad Sci USA 96, 2698-703 (1999).
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 2698-2703
    • Turnbull, J.E.1    Hopwood, J.J.2    Gallagher, J.T.3
  • 30
    • 0014789140 scopus 로고
    • Evidence for the existence of a multichain proteoglycan of heparan sulphate
    • 30 Jansson L, Lindahl U, Evidence for the existence of a multichain proteoglycan of heparan sulphate, Biochem J 117, 699-702 (1970).
    • (1970) Biochem J , vol.117 , pp. 699-702
    • Jansson, L.1    Lindahl, U.2
  • 31
    • 0019820426 scopus 로고
    • Cell-surface heparan sulfate: An intercalated membrane proteoglycan
    • 31 Kjellén L, Pettersson I, Höök M, Cell-surface heparan sulfate: an intercalated membrane proteoglycan, Proc Natl Acad Sci USA 78, 5371-5 (1981).
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 5371-5375
    • Kjellén, L.1    Pettersson, I.2    Höök, M.3
  • 33
    • 0031657808 scopus 로고    scopus 로고
    • Matrix proteoglycans: From molecular design to cellular function
    • 33 Iozzo RV, Matrix proteoglycans: from molecular design to cellular function, Annu Rev Biochem 67, 609-52 (1998).
    • (1998) Annu Rev Biochem , vol.67 , pp. 609-652
    • Iozzo, R.V.1
  • 34
    • 0018068906 scopus 로고
    • A proteoglycan form of heparin and its degradation to single-chain molecules
    • 34 Robinson HC, Horner AA, Höök M, Ögren S, Lindahl U, A proteoglycan form of heparin and its degradation to single-chain molecules, J Biol Chem 253, 6687-93 (1978).
    • (1978) J Biol Chem , vol.253 , pp. 6687-6693
    • Robinson, H.C.1    Horner, A.A.2    Höök, M.3    Ögren, S.4    Lindahl, U.5
  • 36
    • 0014242234 scopus 로고
    • Highly purified antithrombin III with heparin cofactor activity prepared by disc electrophoresis
    • 36 Abildgaard U, Highly purified antithrombin III with heparin cofactor activity prepared by disc electrophoresis. Scand J Clin Lab Invest 21, 89-91 (1968).
    • (1968) Scand J Clin Lab Invest , vol.21 , pp. 89-91
    • Abildgaard, U.1
  • 37
    • 0015853889 scopus 로고
    • Anticoagulant action of heparin
    • 37 Damus PS, Hicks M, Rosenberg RD, Anticoagulant action of heparin, Nature 246, 355-7 (1973).
    • (1973) Nature , vol.246 , pp. 355-357
    • Damus, P.S.1    Hicks, M.2    Rosenberg, R.D.3
  • 39
    • 0017074450 scopus 로고
    • Anticoagulant activity of heparin: Separation of high-activity and low-activity heparin species by affinity chromatography on immobilized antithrombin
    • 39 Höök M, Björk I, Hopwood J, Lindahl U, Anticoagulant activity of heparin: separation of high-activity and low-activity heparin species by affinity chromatography on immobilized antithrombin, FEBS Lett 66, 90-3 (1976).
    • (1976) FEBS Lett , vol.66 , pp. 90-93
    • Höök, M.1    Björk, I.2    Hopwood, J.3    Lindahl, U.4
  • 40
    • 0017044123 scopus 로고
    • Anticoagulant properties of heparin fractionated by affinity chromatography on matrix-bound antithrombin III and by gel filtration
    • 40 Andersson L-O, Barrowcliffe TW, Holmer E, Johnson EA, Sims GEC, Anticoagulant properties of heparin fractionated by affinity chromatography on matrix-bound antithrombin III and by gel filtration, Thromb Res 9, 575-83 (1976).
    • (1976) Thromb Res , vol.9 , pp. 575-583
    • Andersson, L.-O.1    Barrowcliffe, T.W.2    Holmer, E.3    Johnson, E.A.4    Sims, G.E.C.5
  • 41
    • 0001668795 scopus 로고
    • Evidence for a 3-O-sulfated D-glucosamine residue in the antithrombin-binding sequence of heparin
    • 41 Lindahl U, Bäckström G, Thunberg L, Leder IG, Evidence for a 3-O-sulfated D-glucosamine residue in the antithrombin-binding sequence of heparin, Proc Natl Acad Sci USA 77, 6551-5 (1980).
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 6551-6555
    • Lindahl, U.1    Bäckström, G.2    Thunberg, L.3    Leder, I.G.4
  • 43
    • 0027509462 scopus 로고
    • Glycosaminoglycans and the regulation of blood coagulation
    • 43 Bourin M-C, Lindahl U, Glycosaminoglycans and the regulation of blood coagulation, Biochem J 289, 313-30 (1993).
    • (1993) Biochem J , vol.289 , pp. 313-330
    • Bourin, M.-C.1    Lindahl, U.2
  • 46
    • 0031442530 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated?
    • 46 Rosenberg RD, Shworak NW, Liu J, Schwartz JJ, Zhang L, Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated? J Clin Invest 100, S67-75 (1997).
    • (1997) J Clin Invest , vol.100
    • Rosenberg, R.D.1    Shworak, N.W.2    Liu, J.3    Schwartz, J.J.4    Zhang, L.5
  • 47
    • 0031455114 scopus 로고    scopus 로고
    • Antithrombin. A bloody important serpin
    • 47 Bjork I, Olson ST, Antithrombin. A bloody important serpin, Adv Exp Med Biol 425, 17-33 (1997).
    • (1997) Adv Exp Med Biol , vol.425 , pp. 17-33
    • Bjork, I.1    Olson, S.T.2
  • 48
    • 0023664894 scopus 로고
    • Structure and antithrombin-binding properties of heparin isolated from the clams Anomalocardia brasiliana and Tivela mactroides
    • 48 Pejler G, Danielsson Å, Björk I, Lindahl U, Nader HB, Dietrich CP, Structure and antithrombin-binding properties of heparin isolated from the clams Anomalocardia brasiliana and Tivela mactroides, J Biol Chem 262, 11413-21 (1987).
    • (1987) J Biol Chem , vol.262 , pp. 11413-11421
    • Pejler, G.1    Danielsson, A.2    Björk, I.3    Lindahl, U.4    Nader, H.B.5    Dietrich, C.P.6
  • 49
    • 0029795565 scopus 로고    scopus 로고
    • Heparan sulfate - A piece of information
    • 49 Salmivirta M, Lidholt K, Lindahl U, Heparan sulfate - a piece of information, FASEB J 10, 1270-9 (1996).
    • (1996) FASEB J , vol.10 , pp. 1270-1279
    • Salmivirta, M.1    Lidholt, K.2    Lindahl, U.3
  • 50
    • 0028121995 scopus 로고
    • Oligosaccharide sequences of endothelial cell surface heparan sulfate proteoglycan with affinity for lipoprotein lipase
    • 50 Parthasarathy N, Goldberg IJ, Sivaram P, Mulloy B, Flory DM, Wagner WD, Oligosaccharide sequences of endothelial cell surface heparan sulfate proteoglycan with affinity for lipoprotein lipase, J Biol Chem 269, 22391-6 (1994).
    • (1994) J Biol Chem , vol.269 , pp. 22391-22396
    • Parthasarathy, N.1    Goldberg, I.J.2    Sivaram, P.3    Mulloy, B.4    Flory, D.M.5    Wagner, W.D.6
  • 51
    • 0031055886 scopus 로고    scopus 로고
    • Characterization of heparin and heparan sulfate domains binding to the long splice variant of platelet-derived growth factor A chain
    • 51 Feyzi E, Lustig F, Fager G, Spillmann D, Lindahl U, Salmivirta M, Characterization of heparin and heparan sulfate domains binding to the long splice variant of platelet-derived growth factor A chain, J Biol Chem 272, 5518-24 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 5518-5524
    • Feyzi, E.1    Lustig, F.2    Fager, G.3    Spillmann, D.4    Lindahl, U.5    Salmivirta, M.6
  • 52
    • 0026709214 scopus 로고
    • Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor
    • 52 Habuchi H, Suzuki S, Saito T, Tamura T, Harada T, Yoshida K, Kimata K, Structure of a heparan sulphate oligosaccharide that binds to basic fibroblast growth factor, Biochem J 285, 805-13 (1992).
    • (1992) Biochem J , vol.285 , pp. 805-813
    • Habuchi, H.1    Suzuki, S.2    Saito, T.3    Tamura, T.4    Harada, T.5    Yoshida, K.6    Kimata, K.7
  • 53
    • 0027448951 scopus 로고
    • Minimal sequence in heparin/heparan sulfate required for binding of basic fibroblast growth factor
    • 53 Maccarana M, Casu B, Lindahl U, Minimal sequence in heparin/ heparan sulfate required for binding of basic fibroblast growth factor, J Biol Chem 268, 23898-905 (1993).
    • (1993) J Biol Chem , vol.268 , pp. 23898-23905
    • Maccarana, M.1    Casu, B.2    Lindahl, U.3
  • 54
    • 0028575359 scopus 로고
    • Structural requirements in heparin for binding and activation of FGF-1 and FGF-4 are different from that for FGF-2
    • 54 Ishihara M, Structural requirements in heparin for binding and activation of FGF-1 and FGF-4 are different from that for FGF-2, Glycobiology 4, 817-24 (1994).
    • (1994) Glycobiology , vol.4 , pp. 817-824
    • Ishihara, M.1
  • 55
    • 0026727774 scopus 로고
    • Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate
    • 55 Turnbull JE, Fernig DG, Ke Y, Wilkinson MC, Gallagher JT, Identification of the basic fibroblast growth factor binding sequence in fibroblast heparan sulfate, J Biol Chem 267, 10337-41 (1992).
    • (1992) J Biol Chem , vol.267 , pp. 10337-10341
    • Turnbull, J.E.1    Fernig, D.G.2    Ke, Y.3    Wilkinson, M.C.4    Gallagher, J.T.5
  • 56
    • 0032800308 scopus 로고    scopus 로고
    • Characterization of fibroblast growth factor 1 binding heparan sulfate domain
    • 56 Kreuger J, Prydz K, Pettersson RF, Lindahl U, Salmivirta M, Characterization of fibroblast growth factor 1 binding heparan sulfate domain, Glycobiology 9, 723-9 (1999).
    • (1999) Glycobiology , vol.9 , pp. 723-729
    • Kreuger, J.1    Prydz, K.2    Pettersson, R.F.3    Lindahl, U.4    Salmivirta, M.5
  • 57
    • 0034681420 scopus 로고    scopus 로고
    • Elucidation of the structural features of heparan sulfate important for interaction with the Hep-2 domain of fibronectin
    • 57 Lyon M, Rushton G, Askari JA, Humphries MJ, Gallagher JT, Elucidation of the structural features of heparan sulfate important for interaction with the Hep-2 domain of fibronectin, J Biol Chem 275, 4599-606 (2000).
    • (2000) J Biol Chem , vol.275 , pp. 4599-4606
    • Lyon, M.1    Rushton, G.2    Askari, J.A.3    Humphries, M.J.4    Gallagher, J.T.5
  • 58
    • 0030825186 scopus 로고    scopus 로고
    • Structural requirement of heparan sulfate for interaction with Herpes simplex virus type 1 virions and isolated glycoprotein C
    • 58 Feyzi E, Trybala E, Bergström T, Lindahl U, Spillmann D, Structural requirement of heparan sulfate for interaction with Herpes simplex virus type 1 virions and isolated glycoprotein C, J Biol Chem 272, 24850-7 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 24850-24857
    • Feyzi, E.1    Trybala, E.2    Bergström, T.3    Lindahl, U.4    Spillmann, D.5
  • 60
    • 0029866647 scopus 로고    scopus 로고
    • Heparin structure and interactions with basic fibroblast growth factors
    • 60 Faham S, Hileman RE, Fromm JR, Linhardt RJ, Rees DC, Heparin structure and interactions with basic fibroblast growth factors, Science 271, 1116-20 (1996).
    • (1996) Science , vol.271 , pp. 1116-1120
    • Faham, S.1    Hileman, R.E.2    Fromm, J.R.3    Linhardt, R.J.4    Rees, D.C.5
  • 61
    • 0034730725 scopus 로고    scopus 로고
    • The proliferative and migratory activities of breast cancer cells can be differentially regulated by heparan sulfates
    • 61 Nurcombe V, Smart CE, Chipperfield H, Cool SM, Boilly B, Hondermarck H, The proliferative and migratory activities of breast cancer cells can be differentially regulated by heparan sulfates, J Biol Chem 275, 30009-18 (2000).
    • (2000) J Biol Chem , vol.275 , pp. 30009-30018
    • Nurcombe, V.1    Smart, C.E.2    Chipperfield, H.3    Cool, S.M.4    Boilly, B.5    Hondermarck, H.6
  • 62
    • 0025835670 scopus 로고
    • Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation
    • 62 Rapraeger AC, Krufka A, Olwin BB, Requirement of heparan sulfate for bFGF-mediated fibroblast growth and myoblast differentiation, Science 252, 1705-8 (1991).
    • (1991) Science , vol.252 , pp. 1705-1708
    • Rapraeger, A.C.1    Krufka, A.2    Olwin, B.B.3
  • 63
    • 0027428744 scopus 로고
    • Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4
    • 63 Guimond S, Maccarana M, Olwin BB, Lindahl U, Rapraeger AC, Activating and inhibitory heparin sequences for FGF-2 (basic FGF). Distinct requirements for FGF-1, FGF-2, and FGF-4, J Biol Chem 268, 23906-14 (1993).
    • (1993) J Biol Chem , vol.268 , pp. 23906-23914
    • Guimond, S.1    Maccarana, M.2    Olwin, B.B.3    Lindahl, U.4    Rapraeger, A.C.5
  • 64
    • 0032483520 scopus 로고    scopus 로고
    • Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity
    • 64 Pye DA, Vives RR, Turnbull JE, Hyde P, Gallagher JT, Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity, J Biol Chem 273, 22936-42 (1998).
    • (1998) J Biol Chem , vol.273 , pp. 22936-22942
    • Pye, D.A.1    Vives, R.R.2    Turnbull, J.E.3    Hyde, P.4    Gallagher, J.T.5
  • 65
    • 0033532084 scopus 로고    scopus 로고
    • Monomer complexes of basic fibroblast growth factor and heparan sulfate oligosaccharides are the minimal functional unit for cell activation
    • 65 Pye DA, Gallagher JT, Monomer complexes of basic fibroblast growth factor and heparan sulfate oligosaccharides are the minimal functional unit for cell activation, J Biol Chem 274, 13456-61 (1999).
    • (1999) J Biol Chem , vol.274 , pp. 13456-13461
    • Pye, D.A.1    Gallagher, J.T.2
  • 66
    • 0034643323 scopus 로고    scopus 로고
    • Specificities of heparan sulphate proteoglycans in developmental processes
    • 66 Perrimon N, Bernfield M, Specificities of heparan sulphate proteoglycans in developmental processes, Nature 404, 725-8 (2000).
    • (2000) Nature , vol.404 , pp. 725-728
    • Perrimon, N.1    Bernfield, M.2
  • 67
    • 0034191875 scopus 로고    scopus 로고
    • Proteoglycans and pattern formation: Sugar biochemistry meets developmental genetics
    • 67 Selleck SB, Proteoglycans and pattern formation: sugar biochemistry meets developmental genetics, Trends Genet 206-12 (2000).
    • (2000) Trends Genet , pp. 206-212
    • Selleck, S.B.1
  • 68
    • 0014199233 scopus 로고
    • Biosynthesis of heparin. IV. N-deacetylation of a precursor glycosaminoglycan
    • 68 Silbert JE, Biosynthesis of heparin. IV. N-deacetylation of a precursor glycosaminoglycan, J Biol Chem 242, 5153-7 (1967).
    • (1967) J Biol Chem , vol.242 , pp. 5153-5157
    • Silbert, J.E.1
  • 69
    • 0014199198 scopus 로고
    • Biosynthesis of heparin. III. Formation of a sulfated glycosaminoglycan with a microsomal preparation from mast cell tumors
    • 69 Silbert JE, Biosynthesis of heparin. III. Formation of a sulfated glycosaminoglycan with a microsomal preparation from mast cell tumors, J Biol Chem 242, 5146-52 (1967).
    • (1967) J Biol Chem , vol.242 , pp. 5146-5152
    • Silbert, J.E.1
  • 73
    • 0027294764 scopus 로고
    • A single protein catalyzes both N-deacetylation and N-sulfation during the biosynthesis of heparan sulfate
    • 73 Wei Z, Swiedler SJ, Ishihara M, Orellana A, Hirschberg CB, A single protein catalyzes both N-deacetylation and N-sulfation during the biosynthesis of heparan sulfate, Proc Natl Acad Sci USA 90, 3885-8 (1993).
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3885-3888
    • Wei, Z.1    Swiedler, S.J.2    Ishihara, M.3    Orellana, A.4    Hirschberg, C.B.5
  • 74
    • 0028364618 scopus 로고
    • cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an enzyme involved in the biosynthesis of heparin
    • 74 Eriksson I, Sandbäck D, Ek B, Lindahl U, Kjellén L, cDNA cloning and sequencing of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase, an enzyme involved in the biosynthesis of heparin, J Biol Chem 269, 10438-43 (1994).
    • (1994) J Biol Chem , vol.269 , pp. 10438-10443
    • Eriksson, I.1    Sandbäck, D.2    Ek, B.3    Lindahl, U.4    Kjellén, L.5
  • 76
    • 0034681934 scopus 로고    scopus 로고
    • Overexpression of different isoforms of glucosaminyl N-deacetylase/N-sulfotransferase results in distinct heparan sulfate N-sulfation patterns
    • 76 Pikas DS, Eriksson I, Kjellén L, Overexpression of different isoforms of glucosaminyl N-deacetylase/N-sulfotransferase results in distinct heparan sulfate N-sulfation patterns, Biochemistry 39, 4552-8 (2000).
    • (2000) Biochemistry , vol.39 , pp. 4552-4558
    • Pikas, D.S.1    Eriksson, I.2    Kjellén, L.3
  • 77
    • 0033613948 scopus 로고    scopus 로고
    • Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/N-sulfotransferase family
    • 77 Aikawa J, Esko JD, Molecular cloning and expression of a third member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family, J Biol Chem 274, 2690-5 (1999).
    • (1999) J Biol Chem , vol.274 , pp. 2690-2695
    • Aikawa, J.1    Esko, J.D.2
  • 78
    • 0030736088 scopus 로고    scopus 로고
    • Biosynthesis of heparin/heparan sulfate. cDNA cloning and expression of D-glucuronyl C5-epimerase from bovine lung
    • 78 Li J-p, Hagner-McWhirter A, Kjellén L, Palgi J, Jalkanen M, Lindahl U, Biosynthesis of heparin/heparan sulfate. cDNA cloning and expression of D-glucuronyl C5-epimerase from bovine lung, J Biol Chem 272, 28158-63 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 28158-28163
    • Li, J.-P.1    Hagner-McWhirter, A.2    Kjellén, L.3    Palgi, J.4    Jalkanen, M.5    Lindahl, U.6
  • 79
    • 0030925437 scopus 로고    scopus 로고
    • Molecular cloning and expression of Chinese hamster ovary cell heparansulfate 2-sulfotransferase
    • 79 Kobayashi M, Habuchi H, Yoneda M, Habuchi O, Kimata K, Molecular cloning and expression of Chinese hamster ovary cell heparansulfate 2-sulfotransferase, J Biol Chem 272, 13980-5 (1997).
    • (1997) J Biol Chem , vol.272 , pp. 13980-13985
    • Kobayashi, M.1    Habuchi, H.2    Yoneda, M.3    Habuchi, O.4    Kimata, K.5
  • 80
    • 0034161982 scopus 로고    scopus 로고
    • Expression of heparan sulphate L-iduronyl 2-O-sulphotransferase in human kidney 293 cells results in increased D-glucuronyl 2-O-sulphation
    • 80 Rong J, Habuchi H, Kimata K, Lindahl U, Kusche-Gullberg M, Expression of heparan sulphate L-iduronyl 2-O-sulphotransferase in human kidney 293 cells results in increased D-glucuronyl 2-O-sulphation, Biochem J 346, 463-8 (2000).
    • (2000) Biochem J , vol.346 , pp. 463-468
    • Rong, J.1    Habuchi, H.2    Kimata, K.3    Lindahl, U.4    Kusche-Gullberg, M.5
  • 81
    • 0034723420 scopus 로고    scopus 로고
    • The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine
    • 81 Habuchi H, Tanaka M, Habuchi O, Yoshida K, Suzuki H, Ban K, Kimata K, The occurrence of three isoforms of heparan sulfate 6-O-sulfotransferase having different specificities for hexuronic acid adjacent to the targeted N-sulfoglucosamine, J Biol Chem 275, 2859-68 (2000).
    • (2000) J Biol Chem , vol.275 , pp. 2859-2868
    • Habuchi, H.1    Tanaka, M.2    Habuchi, O.3    Yoshida, K.4    Suzuki, H.5    Ban, K.6    Kimata, K.7
  • 82
    • 0033582432 scopus 로고    scopus 로고
    • Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities
    • 82 Liu J, Shworak NW, Sinay P, Schwartz JJ, Zhang L, Fritze LM, Rosenberg RD, Expression of heparan sulfate D-glucosaminyl 3-O-sulfotransferase isoforms reveals novel substrate specificities, J Biol Chem 274, 5185-92 (1999).
    • (1999) J Biol Chem , vol.274 , pp. 5185-5192
    • Liu, J.1    Shworak, N.W.2    Sinay, P.3    Schwartz, J.J.4    Zhang, L.5    Fritze, L.M.6    Rosenberg, R.D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.