Expression and cDNA Cloning of klp-12 Gene Encoding an Ortholog of the Chicken Chromokinesin, Mediating Chromosome Segregation in Caenorhabditis elegans

Journal of Biochemistry and Molecular Biology

Volumn 33, Issue 2, 2000, Pages 138-146

  Ali, M Yusuf ^a   Khan, M L A ^a   Shakir, M A ^a   Kobayashi, K Fukami ^b   Nishikawa, Ken ^b   Siddiqui, Shahid S ^a,c  

^a TOYOHASHI UNIVERSITY OF TECHNOLOGY   (Japan)

^b NATIONAL INSTITUTE OF GENETICS   (Japan)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

C. Elegans; Cell division; Chromokinesin; Chromosomal segregation; KLP 12; Leucine zipper motif

Indexed keywords

EID: 0034398791     PISSN: 12258687     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Ali, M. Y. and Siddiqui, S. S. (2000) cDNA cloning and expression of a C-terminus motor kinesin like protein KLP-17, involved in chromosomal movement in Caenorhabditis elegans. Biochem. Biophys. Res. Commun. 267, 643-650.
2. Ali, M. Y., Siddiqui, Z. K., Malik A. B. and S. S. Siddiqui (2000) cDNA cloning of a novel C-terminal kinesin subfamily, may be involved in chromosomal movement in Caenorhabditis elegans. FEBS Lett. (In press).
3. Altschul, S. F., Warren, G., Webb, M., Eugen, W. M. and David, J. L. (1990) Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
4. Bloom, G. S. and Endow, S. A. (1994) Kinesins. Protein Profile 1, 1059-1116.
5. Clark, D. V., Suleman, D. S., Beckenbach K. A., Gilchrist, E. J. and Baillie, D. V. (1995) Molecular cloning and characterization of the dpy-20 gene of Caenorhabditis elegans. Mol. Gen. Genet. 247, 367-378.
6. Endow, S. A., Henikoff, S. and Niedzela, L. S. (1990) Mediation of meiotic and early mitotic chromosome segregation in Drosophila by a protein related to kinesin. Nature 345, 81-83.
7. Endow S. A. (1999) Microtubule motors in spindle and chromosome motility. Eur J. Biochem. 262, 12-18.
8. Enos, A. P. and Morris N. R. (1990) Mutation of a gene that encodes a kinesin-like protein blocks nuclear division in A. nidulans. Cell 60, 1019-1027
9. Fire, A., Xu, S., Montgomerey, M. K., Kostas, S. A., Driver, S. E. and Mello, C. (1998) Potent and specific genetic interference by double stranded RNA in Caenorhabditis elegans. Nature 391, 806-811.
10. Frishman, D. and Argos, P. (1996) Incorporation of non-local interaction in protein secondary structure prediction from the amino acid sequence. Protein Eng. 9, 133-142.
11. Hagan, I. and Yanagida, M. (1990) Novel potential mitotic motor protein encoded by the fission yeast cut7+ gene. Nature 347, 563-566.
12. Hatsumi, M. and Endow, S. A. (1992) Mutants of microtubule motor protein, non-claret disjuctional, affect spindle structure and chromosome movement in meiosis and mitosis. J. Cell Sci. 101, 547-559.
13. Heck M. M., Pereira, A., Pesavento, P., Yannoni, Y., Spradling, A. C. and Goldstein, L. S. (1993) The Kisen-like protein KLP61F is essential for mitosis in Drosophila. J. Cell Biol.123, 665-679
14. Hirokawa, N. (1998) Kinesin and dynein superfamily proteins and the mechanism of organelle transport. Science 279, 519-526.
15. Hoyt M. A., He L., Loo K. K. and Saunders, W. S. (1992) Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly. J Cell Biol. 118, 109-120
16. Khan, M. L. A., Gogonea, C. B., Siddiqui, Z. K., Ali, M. Y., Kikuno, R., Nishikawa, K. and Siddiqui, S. S. (1997) Molecular cloning and expression of the Caenorhabditis elegans klp-3, an ortholog of C-terminus motor kinesins Kar3 and ncd. J. Mol. Biol. 270, 627-639.
17. Lupas, A., Van Dyke M. and Stock, J. (1991) Predicting coiled coils from protein sequences. Science 252, 1162-1164.
18. Lyu, M. S., Kim, W., Morse H. C. 3rd and Kozak, C. A. (1997) Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein. Mamm Genome 8, 541.
19. Nislow, C., Lombillo, V.A., Kuriyama, R. and McIntosh, J. R. (1992) A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles. Nature 359, 543-547.
20. Patel, N., Thierry-Mieg, D. and Mancillas, J. R. (1993) Cloning by insertional mutagenesis of a cDNA encoding Caenorhabditis elegans kinesin heavy chain. Proc. Natl. Acad. Sci., U.S.A. 90, 9181-9185.
21. Raich, W, B., Moran, A. V., Rothman, J. H. and Hardin, J. (1998) Cytokinesis and midzone microtubule organization in Caenorhabditis elegans require the kinesin like protein ZEN-4. Mol. Biol. Cell 9, 2037-2049.
22. Roof, D. M., Meluh, P. B. and Rose, M. D. (1992) Kinesin-related proteins required for assembly of the mitotic spindle. J. Cell Biol. 118, 95-108
23. Sanger, F., Nicklen, S. and Coulson, A. R. (1977) DNA sequencing with chain-termination inhibitors. Proc. Natl. Acad. Sci., USA. 74, 5463-5467.
24. Sawin, K. E LeGuellec, K., Phillippe M. and Mitchison T. J. (1992) Mitotic spindle organization by a plus-end directed microtubule motor. Nature 359, 540-543.
25. Sekine, Y., Okada, Y., Noda, Y., Kondo, S., Aizawa, H., Takemura, R. and Hirokawa, N. (1994) A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally. J Cell Biol. 127, 187-201.
26. Sellitto, C. and Kuriyama, R. (1988) Distribution of matrix component of the midbody during the cell cycle on Chinese hamster ovary cells. J. Cell Biol. 106, 431-439.
27. Shakir, M. A., Fukushige, T., Yasuda, H., Miwa, J. and Siddiqui, S. S. (1993) C. elegans osm-3 gene mediating osmotic avoidance behavior encodes a kinesin-like protein. Neuroreport 4, 891-894.
28. Sharp, D. J., McDonald, K. L., Brown, H. M., Matthies, H. J., Walczak, C., Vale, R. D., Mitchison, T. J. and Scholey, J. M. (1999) The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles. J. Cell Biol. 144, 25-38
29. Sturtevant, A. H. (1929) The claret mutant type of Drosophila simulans: a study of chromosome elimination and of cell-lineage. Zeitschrift fur Wissenschaftliche Zoologie 135, 323-356.
30. Sublin, E. P., Kull F. J., Cooke, R. and Fletterick, R. J. (1997) Crystal structure of the motor domain of the kinesin-related motor ncd. Nature 380, 555-559.
31. Sulston, J. E., Schierenberg, E., White, J. G. and Thomson, J. N. (1983) The embryonic cell lineage of the nematode Caenorhabditis elegans. Dev. Biol. 100, 64-119.
32. Tabara, H., Motohashi, T. and Kohara Y (1996) A multi-well version of in situ hybridization on whole mount embryos of Caenorhabditis elegans Nucl. Acid Res. 24, 2119-2124.
33. Tabish, M., Siddiqui, Z. K., Nishikawa, K. and Siddiqui, S. S. (1995) Exclusive expression of C. elegans osm-3 kinesin gene in chemosensory neurons open to the external environment. J. Mol. Biol. 247, 377-389.
34. The C. elegans Sequencing consortium (1998) Genome sequence of the nematode C. elegans: a platform for investigating biology. Science 282, 2012-2018.
35. Thomson, J. D., Higgins, D. G. and Gibson, T. J. (1994) CLASTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position specific gap penalties and weight matrix choice. Nucleic Acid Res. 22, 4673-4680.
36. Vernos, I., Raats, J., Hirano, T., Heasman, J., Karsenti, E. and Wylie, C. (1995) Xklp1, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning. Cell 81, 117-127.
37. Wang, S. Z. and Adler, R. (1995) Chromokinesin: a DNA-binding, kinesin-like nuclear protein. J. Cell Biol. 128, 761-768
38. Wilson, R. et al. (1994) 2.2 Mb of contiguous nucleotide sequence from chromosomes III of C. elegans. Nature 368, 32-38.
39. Wright, B. D. and Scholey, J. M. (1992) Microtubule motors in the early sea urchin embryos. Curr. Top. Dev. Biol. 26, 71-91.
40. Yan, R. T and Wang, S. Z. (1997) Increased chromokinesin immunoreactivity in retinoblastoma cells. Gene 189, 263-267.