Increased Chromokinesin immunoreactivity in retinoblastoma cells

Gene

Volumn 189, Issue 2, 1997, Pages 263-267

  Yan, Run Tao ^a   Wang, Shu Zhen ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Chromosomal motor; Gene expression; Kinesin like protein; Sequence

Indexed keywords

CHROMOKINESIN; KINESIN; UNCLASSIFIED DRUG;

ANTIBODY AFFINITY; ARTICLE; CELL CULTURE; CHROMOSOME; CHROMOSOME ARM; CONTROLLED STUDY; FIBROBLAST; FIBROBLAST CULTURE; HUMAN; HUMAN CELL; IMMUNOAFFINITY CHROMATOGRAPHY; IMMUNOREACTIVITY; INTERPHASE; MITOSIS; MITOSIS RATE; PRIORITY JOURNAL; REGULATORY MECHANISM; RETINOBLASTOMA; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODY SPECIFICITY; BASE SEQUENCE; CHICK EMBRYO; CLONING, MOLECULAR; DNA-BINDING PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; KINESIN; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; RECOMBINANT FUSION PROTEINS; RETINOBLASTOMA; TUMOR CELLS, CULTURED;

EID: 0030903519     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(96)00860-8     Document Type: Article

References (17)

1. Almasan, A., Mangelsdorf, D.J., Ong, E.S., Wahl, G.M. and Evans, R.M. (1995) Deficiency of retinoblastoma protein leads to inappropriate S-phase entry, activation of E2F-responsive genes, and apoptosis. Proc. Natl. Acad. Sci. USA 92, 5436-5440.
2. Dryja, T.P. (1995) Molecular genetics of retinoblastoma. IOVS Suppl. 36, 220.
3. Fuller, M.T. (1995) Riding the polar winds: chromosomes motor down east. Cell 81, 5-8.
4. Kashina, A.S., Baskin, R.J., Cole, D.G., Wedaman, K.P., Saxton, W.M. and Scholey, J.M. (1996) A bipolar kinesin. Nature 379, 270-272.
5. Liao, H., Li, G., and Yen, T.J. (1994) Mitotic regulation of microtubule cross-linking activity of CENP-E kinetochore protein. Science 265, 394-398.
6. McIntosh, J.R. (1994) The roles of microtubules in chromosome movement. In: Microtubules, pp. 413-434, Wiley-Liss, New York.
7. Poulsen, G.L, and Nork, T.M. (1995) Programmed cell death (apoptosis) is a prominent feature of retinoblastoma. IVOS Suppl. 36, 495.
8. Scholey, J.M., Heuser, J., Yang, J.T., and Goldstein, L.S.B. (1989) Identification of globular mechanochemical heads of kinesin. Nature 338, 355-357.
9. Sekine, Y., Okada, Y., Noda, Y., Kondo, S., Aizawa, H. and Takemura, R. (1994) A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally. J. Cell Biol. 127, 187-201.
10. Skoufias, D.A. and Scholey, J.M. (1993) Cytoplasmic microtubule-based motor proteins. Curr. Opin. Cell Biol. 5, 95-104.
11. Smith, M.L. and Fornace Jr., A.J. (1995) Genomic instability and the role of p53 mutations in cancer cells. Curr. Opin. Oncol. 7, 69-75.
12. Vernos, I., Raats, J., Hirano, T., Heasman, J., Karsenti, E. and Wylie, C. (1995) Xklpl, a chromosomal Xenopus kinesin-like protein essential for spindle organization and chromosome positioning. Cell 81, 117-127.
13. Walczak, C.E. and Mitchison, T.J. (1996) Kinesin-related proteins at mitotic spindle poles: function and regulation. Cell 85, 943-946.
14. Wang, S.-Z. and Adler, R. (1994) A developmentally regulated basic-leucine zipper-like gene and its expression in embryonic retina and lens. Proc. Natl. Acad. Sci. USA 91, 1351-1355.
15. Wang, S.-Z. and Adler, R. (1995) Chromokinesin: a DNA-binding, kinesin-like nuclear protein. J. Cell Biol. 128, 761-768.
16. Yang, J.T., Laymon, R.A. and Goldstein, L.S.B. (1989) A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analysis. Cell 56, 879-889.
17. Yen, T.J., Compton, D.A., Wise, D., Zinkowski, R.P. Brinkley, B.R., Earnshaw, W.C. and Cleveland, D.W. (1991) CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. EMBO J. 10, 1245-1254.