The changes in body weight and plasma metabolite levels during leptin injection are caused by the reduction of food intake in sheep

Animal Science

Volumn 70, Issue 2, 2000, Pages 343-348

  Tokuda, T ^a,b   Matsui, T ^a   Ito, J ^a   Torii, S ^a   Yano, H ^a  

^a KYOTO UNIVERSITY   (Japan)

^b SHIMANE UNIVERSITY   (Japan)

Author keywords

Body weight; Fatty acids; Food intake; Glucose; Sheep

Indexed keywords

EID: 0034396096     PISSN: 13577298     EISSN: None     Source Type: Journal    
DOI: 10.1017/S1357729800054801     Document Type: Article

References (28)

1. Baile, C. A., Krabill, L. F. and Simpson, C. W. 1973. Feeding elicited by A- and B-adrenocepter agonists in sheep and cattle. Pharmacology, Biochemistry and Behaviour 1: 531-538.
2. Barb, C. R., Van, X., Azain, M. J., Kraeling, R. R., Rampacek, G. B. and Ramsay, T. G. 1998. Recombinant porcine leptin reduces feed intake and stimulates growth hormone secretion in swine. Domestic Animal Endocrinology 15: 77-86.
3. Bines, J. A. 1972. The effect on intake of concentration of exchanging rumen contents between fed and unfed cows. Proceedings of the Nutrition Society 31: 46A-46B.
4. Bines, J. A., Suzuki, S. and Balch, C. C. 1969. The quantitative significance of long-term regulation of food intake in the cow. British Journal of Nutrition 23: 695-704.
5. Campfield, L. A., Smith, F. J., Guisez, Y., Devos, R. and Burn, P. 1995. Recombinant mouse ob protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269: 546-549.
6. Caro, J. F., Sinha, M. K., Kolaczynski, J. W., Zhang, P. L. and Considine, R. V. 1996. Leptin: the tale of an obesity gene. Diabetes 45: 1455-1462.
7. Considine, R. V., Sinha, M. K., Heiman, M. L., Kriauciunas, A., Stephens, T. W., Nyce, M. R., Ohannesian, J. P., Marco, C. C., McKee L. J. and Bauer, T. L. 1996. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. New England Journal of Medicine 334: 292-295.
8. Dijk, G. van, Donahey, J. C. K., Thiele, T. E., S̊cheurink, A. J. W., Steffens, A. B., Wilkinson, C. W., Tenenbaum, R., Campfield, L. A., Burn, P., Seely, R. J. and Woods, S. C. 1997. Central leptin stimulates corticosterone secretion at the onset of the dark phase. Diabetes 46: 1911-1914.
9. Forbes, J. M. 1968. The physical relationships of the abdominal organs in the pregnant ewe. Journal of Agricultural Science, Cambridge 70: 171-177.
10. Forbes, J. M. 1969. The effect of pregnancy and fatness on the volume of the rumen contents in the ewe. Journal of Agricultural Science, Cambridge 72: 119-121.
11. Fruhbeck, G., Aguado, M. and Martinez, J. A. 1997. In vitro lipolytic effect of leptin on mouse adipocytes: evidence for a possible autocrine/paracrine role of leptin. Biochemical and Biophysical Research Communications 240: 590-594.
12. Fruhbeck, G., Aguado, M., Gomez-Ambrosi, J. and Martinez, J. A. 1998. Lipolytic effect of in vivo leptin administration on adipocytes of lean and ob/ob mice, but not db/db mice. Biochemical and Biophysical Research Communications 250: 99-102.
13. Halaas, J. L., Boozer, C., Blair-West, J., Fidahusein, N., Denton, D. A. and Friedman, J. M. 1997. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proceedings of the National Academy of Sciences of the United States of America 94: 8878-8883.
14. Henry, B. A., Goding, J. W., Alexander, A. J., Tilbrook, A. J., Canny, B. J., Du, D., Alexandra, R. A. O., Ashley, M. and lain, J. C. 1999. Central administration of leptin to ovariectomized ewes inhibits food intake without affecting the secretion of hormones from the pituitary gland: evidence for a dissociation of effects on appetite and neuroendocrine function. Endocrinology 140: 1175-1182.
15. Kamohara, S., Burcelin, R., Halaas, J. L., Friedman, J. M. and Charron, M. J. 1997. Acute stimulation of glucose metabolism in mice by leptin treatment. Nature 389: 374-377.
16. Landt, M., Gingerich, R. L., Havel, P. J., Mueller, W. M., Schoner, B., Hale, J. E. and Heiman, M. L. 1998. Radioimmunoassay of rat leptin: sexual dimorphism reversed from humans. Clinical Chemistry 44: 565-570.
17. Minton, J. E., Bindel, D. J., Drouillard, J. S., Titgemeyer, E. C., Grieger, D. M. and Hill, C. M. 1998. Serum leptin is associated with carcass traits in finishing cattle. Journal of Dairy Science 81: (suppl. 1), p. 231.
18. Mistry, A. M., Swick, A. G. and Romsos, D. R. 1997. Leptin rapidly lowers food intake and metabolic rates in lean and ob/ob mice. Journal of Nutrition 127: 2065-2072.
19. Naqvi, S. M. K. and Rai, A. K. 1991. Effect of fasting on some physiological responses and blood constitutions in native and crossbred sheep. Indian Journal of Animal Sciences 61: 985-990.
20. Oshiro, S. 1985. Effects of forced feeding on physiological responses in goats: ruminating behaviors. Japanese Society of Zootechnical Science 56: 312-317.
21. Pelleymounter, M. A., Cullen, M. J., Baker, M. B., Hecht, R., Winters, D., Soone, T. and Collins, F. 1995. Effects of the obese gene-product on body-weight regulation in ob/ob mice. Science 269: 540-543.
22. Schwartz, M. W., Seeley, R. J., Campfield, L. A., Burn, P. and Baskin, D. G. 1996. Identification of targets of leptin action in rat hypothalamus. Journal of Clinical Investigation 98: 1101-1106.
23. Siegrist-Kaiser, C. A., Pauli, V., Juge-Aubry, C. E., Boss, O., Pernin, A., Chin, W. W., Cusin, I., Rohner-Jeanrenaud, F., Burger, A. G., Zapf, J. and Meier, C. A. 1997. Direct effects of leptin on brown and white adipose tissue. Journal of Clinical Investigation 100: 2858-2864.
24. Sivitz, W. I., Walsh, S. A., Morgan, D. A., Thomas, M. J. and Haynes, W. G. 1997. Effects of leptin on insulin sensitivity in normal rats. Endocrinology 138: 3395-3401.
25. Statistical Analysis Systems Institute. 1985. SAS user's guide: statistics version 5 edition. SAS Institute Inc., Cary, NC.
26. Statistical Analysis Systems Institute. 1996. SAS/STAT software: changes and enhancements through release 6.11. SAS Institute Inc, Cary, NC.
27. Tartaglia, L. A., Dembski, M., Weng, X., Deng, N., Culpepper, J., Deros, R., Richards, G. J., Campfield, L. A., Clark, F. T., Deeds, J., Muir, C., Sanker, S., Moriarty, A., Moore, K. J., Smutko, J. S., Mays, G. G., Woolf, E. A., Monroe, C. A. and Tepper, R. I. 1995. Identification and expression cloning of a leptin receptor, OB-R. Cell 83: 1263-1271.
28. Tokuda, T., Ito, J., Torii, S., Matsui, T. and Yano, H. 1998. Intracerebroventricular injection of leptin decreased feed intake and body weight in sheep. Proceedings of the eighth world conference on animal production, Seoul, Korea, vol. 1, pp. 948-949.