Risk ratio as parameter for the genetic characterization of complex binary traits in cattle. A simulation study under various genetic models using halfsib families

Journal of Animal Breeding and Genetics

Volumn 117, Issue 3, 2000, Pages 153-167

  Thaler Neto, A ^a,b   Fries, R ^a   Thaller, G ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b SANTA CATARINA STATE UNIVERSITY   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

BOS TAURUS;

EID: 0034380661     PISSN: 09312668     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1439-0388.2000.00246.x     Document Type: Article

References (27)

1. BRZUSTOWICZ, L. M., 1998: Molecular genetic approaches to the study of language. Hum. Biology 70: 325-345.
2. COLLINS, A.; MORTON, N. E., 1995: Nonparametric tests for linkage with dependent sib pairs. Hum. Heredity 45: 311-318.
3. DUDA, J., 1988: Populationsgenetische Analyse der Mastitisanfälligkeit in Oberbayerischen Kuhbeständen. Dissertation. Lehrstuhl für Tierzucht, Technische Universität München, Freising.
4. EDGINGTON, E., 1995: Randomisation Tests. 3rd edn, Statistic: Textbooks and Monographs, 147. Marcell Dekker, New York.
5. FALCONER, D. S., 1965: The inheritance of liability to certain disease, estimated from the incidence among relatives. Ann. Human Genetic 29: 51-76.
6. FALCONER, D. S.; MACKAY, T. F. C., 1996. Introduction to Quantitative Genetics, 4th edn. Longmans. London.
7. GHOSH, S.; COLLINS, F. S., 1996: The geneticist's approach to complex disease. Annu. Rev. Medicine 47: 333-353.
8. GIANOLLA, D.; FOULLEY, J. L., 1983: Sire evaluation for ordered categorical data with a threshold model. Genet. Sel. Evol. 15: 201-223.
9. GOOD, P., 1994: Permutation tests. A Practical Guide to Resampling Methods for Testing Hypotheses. Springer-Verlag, New York.
10. GU, C.; RAO, D. C., 1997a: A linkage strategy for detection of human quantitative-trait loci. I. Generalized relative risk ratios and power of sib pairs with extreme trait values. Am. J. Hum. Genet. 61: 200-210.
11. GU, C.; RAO, D. C., 1997b: A linkage strategy for detection of human quantitative-trait loci. II. Optimization of study designs based on extreme sib pairs and generalized relative risk ratios. Am. J. Hum. Genet. 61: 211-222.
12. GUO, S. W., 1998: Inflation of sibling recurrence-risk ratio, due to ascertainment bias and/or over-reporting. Am. J. Hum. Genet. 63: 252-258.
13. HARTL, D. L.; MARUYAMA, T., 1968: Phenogram enumeration: the number of regular genotype-phenotype correspondence in genetic systems. J. Theoret. Biol. 20: 129-163.
14. HODGE, S. E., 1984: The information contained in multiple sibling pairs. Genet. Epidemiol. 1: 109-122.
15. HOESCHELE, I.; TIER, B., 1995: Estimation of variance components of threshold characters by marginal posterior models and means via Gibbs sampling. Genet. Sel. Evol 27: 519-540.
16. JAMES, J. B., 1971: Frequency in relatives for an all-or-none-trait. Ann. Human Genet. 35: 47-49.
17. LANDER, E.; SCHORK, N., 1994: Genetic dissection of complex traits. Science 265: 237-247.
18. LYNCH, M.; WALSH, B., 1998: Genetic Analysis of Quantitative Traits. Sinauer Associates, Sunderland, MA.
19. MORTON, N. E., 1997: Genetic epidemiology. Ann. Human Genet. 1: 1-13.
20. PENROSE, L. S., 1953: The genetic background of common diseases. Acta Genet. 4: 257-265.
21. RISCH, N., 1990a: Linkage strategies for genetically complex traits. I. Multilocus models. Am. J. Hum. Genet. 46: 222-228.
22. RISCH, N., 1990b: Linkage strategies for genetically complex traits. II. The power of affected relative pairs. Am. J. Hum. Genet. 46: 229-241.
23. RISCH, N., 1990c: Linkage strategies for genetically complex traits. III. The effect of marker polymorphism on analysis of affected relative pairs. Am. J. Hum. Genet. 46: 242-253.
24. SUAREZ, B. K.; HODGE, S. E., 1979: A simple method to detect linkage for rare recessive diseases: an application to juvenile diabetes. Clin. Genet 15: 126-136.
25. TERWILLIGER, J. D., WEISS, K. M., 1998: Linkage disequilibrium mapping of complex disease: fantasy or reality? Curr. Opin. Biotechnol. 9: 578-594.
26. WELLER, J. I.; KASHI, Y.; SOLLER, M., 1990: Power of daugther and grandaugther desingns for determining linkage between marker loci and QTL in dairy cattle. J. Dairy Sci. 73: 2525-2537.
27. WILSON, A. F.; ELSTON, R. C., 1993: Statistical validity of the Haseman-Elston sib-pair test in small samples. Genet Epidemiol. 10: 593-598.