The neuroimmune interface in prion diseases

News in Physiological Sciences

Volumn 15, Issue 5, 2000, Pages 250-255

  Klein, Michael A ^a   Aguzzi, Adriano ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034367386     PISSN: 08861714     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiologyonline.2000.15.5.250     Document Type: Article

References (15)

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3. Büeler HR, Aguzzi A, Sailer A, Greiner RA, Autenried P, Aguet M, and Weissmann C. Mice devoid of PrP are resistant to scrapie. Cell 73: 1339-1347, 1993.
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5. Fraser H, Farquhar CF, McConnell I, and Davies D. The scrapie disease process is unaffected by ionising radiation. Prog Clin Biol Res 317: 653-658, 1989.
6. Kimberlin RH and Walker CA. The role of the spleen in the neuroinvasion of scrapie in mice. Virus Res 12: 201-211, 1989.
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8. Klein MA, Frigg R, Flechsig E, Raeber AJ, Kalinke U, Bluethmann H, Bootz F, Suter M, Zinkernagel RM, and Aguzzi A. A crucial role for B cells in neuroinvasive scrapie. Nature 390: 687-690, 1997.
9. Klein MA, Frigg R, Raeber AJ, Flechsig E, Hegyi I, Zinkernagel RM, Weissmann C, and Aguzzi A. PrP expression in B lymphocytes is not required for prion neuroinvasion. Nat Med 4: 1429-1433, 1998.
10. Lasmezas CI, Cesbron JY, Deslys JP, Demaimay R, Adjou KT, Rioux R, Lemaire C, Locht C, and Dormont D: Immune system-dependent and -independent replication of the scrapie agent. J Virol 70: 1292-1295, 1996.
11. Prusiner SB. Prion diseases and the BSE crisis. Science 278: 245-251, 1997.
12. Raeber AJ, Klein MA, Frigg R, Flechsig E, Aguzzi A, and Weissmann C. PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice. EMBO J 18: 2702-2706, 1999.
13. Sakaguchi S, Katamine S, Nishida N, Moriuchi R, Shigematzu K, Sugimoto T, Nakatni A, Kataoka Y, Houtani H, Shirabe S, Okada H, Hasegawa S, Myamoto T, and Noda T. Loss of cerebellar Purkinje Cells in aged mice homozygous for a disrupted PrP gene. Nature 380: 528-531, 1996.
14. Straub RH, Westermann J, Scholmerich J, and Falk W. Dialogue between the CNS and the immune system in lymphoid organs. Immunol Today 19: 409-413, 1998.
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