ΔFosB: A molecular switch underlying long-term neural plasticity

Current Opinion in Neurology

Volumn 13, Issue 6, 2000, Pages 715-720

  Kelz, Max B ^a   Nestler, Eric J ^b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

BRAIN DEPTH STIMULATION; DRUG DEPENDENCE; GENE INDUCTION; MOTOR DYSFUNCTION; NERVE CELL PLASTICITY; REVIEW; SIGNAL TRANSDUCTION; ADDICTION; ANIMAL; GENETICS; HUMAN; PHYSIOLOGY;

ANIMALS; HUMANS; MOVEMENT DISORDERS; NEURONAL PLASTICITY; SUBSTANCE-RELATED DISORDERS; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS;

EID: 0034353226     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019052-200012000-00017     Document Type: Review

References (55)

1. Initiation and adaptation: A paradigm for understanding psychotropic drug action
2. AP-1 function and regulation
3. Alternative splicing of fosB transcripts results in differentially expressed mRNAs encoding functionally antagonistic proteins
4. Coordinate regulation of Fos and Jun proteins in mouse brain by LiCl
5. Selective effects of alcohol drinking on restraint-induced expression of immediate early genes in mouse brain
6. MK-801-induced expression of Fos protein family members in the rat retrosplenial granular cortex
7. A short conserved motif is required for repressor domain function in the myeloid-specific transcription factor CCAAT/enhancer-binding protein epsilon
8. Engagement of natural cytotoxicity programs regulates AP-1 expression in the NKL human NK cell line
9. Transformation by ras modifies AP1 composition and activity
10. The repertoire of fos and jun proteins expressed during the G1 phase of the cell cycle is determined by the duration of mitogen-activated protein kinase activation
11. Enterocyte-like differentiation of the Caco-2 intestinal cell line is associated with increases in AP-1 protein binding
12. Differential effect on U937 cell differentiation by targeting transcriptional factors implicated in tissue- or stage-specific induced integrin expression
13. A dominant-negative mutant of c-Jun inhibits cell cycle progression during the transition of CD4(-)CD8(-) to CD4(+)CD8(+) thymocytes
14. Differential regulation of IL-6 promoter activity in a human ovarian-tumor cell line transfected with various p53 mutants: Involvement of AP-1
15. Expression pattern of the AP-1 family in breast cancer: Association of fosB expression with a well-differentiated, receptor-positive tumor phenotype
16. Taxotere activates transcription factor AP-1 in association with apoptotic cell death in gastric cancer cell lines
17. Specific regulation of fos family transcription factors in thymocytes at two developmental checkpoints
18. Conversion of HPV 18 positive non-tumorigenic HeLa-fibroblast hybrids to invasive growth involves loss of TNF-alpha mediated repression of viral transcription and modification of the AP-1 transcription complex
19. Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments
20. Regulation of ΔFosB and FosB-like proteins by electroconvulsive seizure (ECS) and cocaine treatments
21. Chronic Fos-related antigens: Stable variants of ΔFosB induced in brain by chronic treatments
22. Extracellular signal-regulated kinase 1/2-mediated phosphorylation of JunD and FosB is required for okadaic acid-induced activator protein 1 activation
23. Inhibition of p38 MAP kinase increases okadaic acid mediated AP-1 expression and DNA binding but has no effect on TRE dependent transcription
24. Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice
25. Prolonged expression of AP-1 transcription factors in the rat hippocampus after systemic kainate treatment
26. Implications of prolonged expression of Fos-related antigens
27. FosB mutant mice: Loss of chronic cocaine induction of Fos-related proteins and heightened sensitivity to cocaine's psychomotor and rewarding effects
28. Absence of a persistently elevated 37 kDa fos-related antigen and AP-1-like DNA-binding activity in the brains of kainic acid-treated fosB null mice
29. Immediate-early genes: Ten years on
30. Pharmacological studies of the regulation of chronic FOS-related antigen induction by cocaine in the striatum and nucleus accumbens
31. Network-level changes in expression of inducible Fos-Jun proteins in the striatum during chronic cocaine treatment and withdrawal
32. Induction of chronic Fos-related antigens in rat brain by chronic morphine administration
33. Common neural substrates for the addictive properties of nicotine and cocaine
34. Repeated alcohol administration differentially affects c-Fos and FosB protein immunoreactivity in DBA/2J mice
35. Region-specific induction of deltaFosB by repeated administration of typical versus atypical antipsychotic drugs
36. Chronic electroconvulsive seizure (ECS) treatment results in expression of a long-lasting AP-1 complex in brain with altered composition and characteristics
37. Striatal fosB expression is causally linked with L-DOPA-induced abnormal involuntary movements and the associated upregulation of striatal prodynorphin mRNA in a rat model of Parkinson's disease
38. Chronic alterations in dopaminergic neurotransmission produce a persistent elevation of delta-FosB-like protein(s) in both the rodent and primate striatum
39. Compartmental changes in expression of c-Fos and FosB proteins in intact and dopamine-depleted striatum after chronic apomorphine treatment
40. Contrasting effects of chronic clozapine, Seroquel(TM) (ICI 204,636) and haloperidol administration on deltaFosB-like immunoreactivity in the rodent forebrain
41. Atypical and typical neuroleptic treatments induce distinct programs of transcription factor expression in the striatum
42. Ischemia-induced CA1 neuronal death is preceded by elevated FosB and jun expression and reduced NGFI-A and JunB levels
43. Control of the tissue inhibitor of metalloproteinases-1 promoter in culture-activated rat hepatic stellate cells: Regulation by activator protein-1 DNA binding proteins
44. Neuropharmacological mechanisms of drug reward: Beyond dopamine in the nucleus accumbens
45. The role of excitatory amino acids in behavioral sensitization to psychomotor stimulants
46. Expression of the transcription factor deltaFosB in the brain controls sensitivity to cocaine
47. Changes in the regional and compartmental distribution of FosB- and JunB-like immunoreactivity induced in the dopamine-denervated rat striatum by acute or chronic L-DOPA treatment
48. 1-class dopamine receptors influence cocaine-induced persistent expression of Fos-related proteins in striatum
49. The functional anatomy of basal ganglia disorders
50. Quantitative recording of rotational behavior in rats after 6-hydroxydopamine lesions of the nigrostriatal dopamine system
51. The unilateral 6-hydroxydopamine lesion model in behavioral brain research. Analysis of functional deficits, recovery and treatments
52. Characterization of enhanced behavioral responses to L-DOPA following repeated administration in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease
53. 1-Receptor-related priming is attenuated by antisense-meditated 'knockdown' of fosB expression
54. Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity
55. The effects of antipsychotic drugs on Fos protein expression in the prefrontal cortex: Cellular localization and pharmacological characterization