Arabidopsis RopGAPSs are a novel family of Rho GTPase-activating proteins that require the Cdc42/Rac-interactive binding motif for Rop-specific GTPase stimulation

Plant Physiology

Volumn 124, Issue 4, 2000, Pages 1625-1636

  Wu, G ^a   Li, H ^a   Yang, Z ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINUM FLUORIDE; CELL DEATH; ENZYME ACTIVITY; ENZYME REGULATION; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; HYDROGEN PEROXIDE; IN VITRO CULTURE; MUTANT PROTEIN; POLLEN TUBE GROWTH; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; RAC1 PROTEIN; REACTION MECHANISM; TWO HYBRID SYSTEM;

ARABIDOPSIS; EMBRYOPHYTA; MAMMALIA;

ALUMINUM DERIVATIVE; COMPLEMENTARY DNA; FLUORIDE; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; GUANOSINE TRIPHOSPHATE; PROTEIN CDC42; RHO GTPASE ACTIVATING PROTEIN; RHO GTPASE-ACTIVATING PROTEIN; TETRAFLUOROALUMINATE;

ARABIDOPSIS; ARTICLE; BINDING COMPETITION; BINDING SITE; CHEMISTRY; DNA SEQUENCE; DRUG EFFECT; ENZYMOLOGY; GENE DELETION; GENETICS; METABOLISM; MUTATION; PROTEIN BINDING; SEQUENCE ALIGNMENT;

ALUMINUM COMPOUNDS; ARABIDOPSIS; BINDING SITES; BINDING, COMPETITIVE; CDC42 GTP-BINDING PROTEIN; DNA, COMPLEMENTARY; FLUORIDES; GTPASE-ACTIVATING PROTEINS; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; MUTATION; PROTEIN BINDING; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION;

EID: 0034353114     PISSN: 00320889     EISSN: None     Source Type: Journal    
DOI: 10.1104/pp.124.4.1625     Document Type: Article

References (56)

1. Structure of Cdc42 in complex with the GTPase-binding domain of the "Wiskott-Aldrich syndrome" protein
2. A Drosophila rotund transcript expressed during spermatogenesis and imaginal disc morphogenesis encodes a protein that is similar to human Rac GTPase-activating (racGAP) proteins
3. Plant cell growth and differentiation may involve GAP regulation of Rac activity
4. A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases
5. Genes for small GTP-binding proteins analogous to mammalian Rac are preferentially expressed in developing cotton fibers
6. Signaling and the modulation of pollen tube growth
7. Signaling in pollination
8. Latrunculin B has different effects on pollen germination and tube growth
9. Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
10. Fluoride activation of the Rho family GTP-binding protein Cdc42Hs
11. A dual functional signal mediator showing RhoGAP and phospholipase C-δ stimulating activities
12. The small GTP-binding protein rac is a regulator of cell death in plants
13. Protein-protein interactions among the Aux/IAA proteins
14. Rac homologues and compartmentalized phosphatidylinositol 4, 5-bisphosphate act in a common pathway to regulate polar pollen tube growth
15. GAPs for rho-related GTPases
16. CdGAP, a novel prolinerich GTPase-activating protein for Cdc42 and Rac
17. Characterization of rhoGAP: A GTPase-activating protein for rho-related small GTPases
18. Arabidopsis thaliana "extralarge GTP-binding proteins" (AtXLG1): A new class of G-proteins
19. Biochemical studies of the mechanism of action of the Cdc42-GTPase-activating protein
20. Myotonic dystrophy kinase-related Cdc42-binding kinase acts as a Cdc42 effector in promoting cytoskeletal reorganization
21. Control of pollen tube tip growth by a Rop GTPase-dependent pathway that leads to the tip-localized calcium influx
22. Arabidopsis Rho-Related GTPases: Differential gene expression in pollen and polar localization in fission yeast
23. Rho GTPase and the actin cytoskeleton
24. Structural determinants required for the interaction between Rho GTPase and the GTPase-activating domain of p190
25. Localization of a rho GTPase implies a role in tip growth and movement of the generative cell in pollen tubes
26. Inhibition of pollen tube elongation by microinjected anti-Rop1Ps antibodies suggests a crucial role for Rho-type GTPases in the control of tip growth
27. Molecular cloning and characterization of GPA1, a G protein α-subunit gene from Arabidopsis thaliana
28. Calcium channel activity during pollen tube growth and reorientation
29. A brain serine/threonine protein kinase activated by Cdc42 and Rac1
30. Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK
31. Distinct cellular effects and interactions of the Rho-family GTPase TC10
32. The involvement of hydrogen peroxide in the differentiation of secondary walls in cotton fibers
33. Identification of a ten-amino acid proline-rich SH3 binding site
34. Signal transduction through the GTPbinding proteins Rac and Rho
35. Rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo
36. Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transitionstate analogue
37. GTPase-activating proteins: Helping hands to complement an active site
38. The Ras- RasGAP complex: Structural basis for GTPase activation and its loss in oncogenic Ras mutants
39. G proteins in signal transduction
40. Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization
41. The human active breakpoint cluster region-related gene encodes a brain protein with homology to guanine nucleotide exchange proteins and GTPase-activating proteins
42. Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton
43. The function of the p190 Rho GTPase-activating protein is controlled by its N-terminal GTP binding domain
44. CLV3 is required for the assembly of Arabidopsis CLV1 receptor-like kinase into a signaling complex that induces KAPP and a Rop-like GTPase
45. Evidence for distinct mechanisms of transition state stabilization of GTPases by fluoride
46. Isolation of cDNAs encoding guanine nucleotide-binding protein β-subunit homologues from maize (ZGB1) and Arabidopsis (AGB1)
47. Dbl family proteins
48. Cloning and characterization of rac-like cDNAs from Arabidopsis thaliana
49. Signaling tip growth in plants
50. Molecular cloning and characterization of rho, a ras-related small GTP-binding protein from the garden pea
51. Interaction of Rac1 with GTPase-activating proteins and putative effectors: A comparison with Cdc42 and RhoA
52. Characterization of the interactions between the small GTPase Cdc42 and its GTPase-activating proteins and putative effectors: Comparison of kinetic properties of Cdc42 binding to the Cdc42-interactive domains
53. The Rop GTPase switch turns on polar growth in pollen
54. The Rop GTPase: An emerging signaling switch in plants