NiCl2 and amiloride induce spreading depression in guinea pig hippocampal slices

Cephalalgia

Volumn 20, Issue 8, 2000, Pages 740-747

  Gorji, A ^a   Scheller, D ^b   Tegtmeier, F ^b   Kohling R ^a   Straub, H ^a   Speckmann, E J ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b JANSSEN CILAG GMBH   (Germany)

Author keywords

Calcium antagonists; Glutamate; Headache; Spreading depression

Indexed keywords

AMILORIDE; CALCIUM CHANNEL T TYPE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; NICKEL CHLORIDE; 2 AMINO 5 PHOSPHOPENTANOIC ACID; 2-AMINO-5-PHOSPHOPENTANOIC ACID; CALCIUM CHANNEL BLOCKING AGENT; DRUG DERIVATIVE; N METHYLASPARTIC ACID; NICKEL; VALINE;

ANIMAL TISSUE; ARTICLE; BRAIN ISCHEMIA; BRAIN SLICE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE ASSOCIATION; GUINEA PIG; HIPPOCAMPUS; MIGRAINE; NONHUMAN; SPREADING CORTICAL DEPRESSION; ANIMAL; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ELECTROPHYSIOLOGY; IN VITRO STUDY; PHYSIOLOGY;

AMILORIDE; ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; GUINEA PIGS; HIPPOCAMPUS; N-METHYLASPARTATE; NICKEL; SPREADING CORTICAL DEPRESSION; VALINE;

EID: 0034352036     PISSN: 03331024     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1468-2982.2000.00124.x     Document Type: Article

References (38)

1. Spreading depression of actieity in the cerebral cortex
2. Subcortical cerebral blood flow and metabolic changes elicited by cortical spreading depression in rat
3. Biochemical effects of cerebral ischemia: Relevance to migraine
4. Extracellular ionic variations during spreading depression
5. Imaging spreading depression and associated intracellular calcium waves in brain slices
6. Modulation of extracellular calcium and its functional implications
7. Extracellular ion concentrations during spreading depression and ischemia in the rat brain cortex
8. Calcium waves precede electrophysiological changes of spreading depression in hippocampal organ cultures
9. 2 EDTA) topical treatment of rat cerebral cortex
10. Suppression of epileptiform burst discharges in CA3 neurons of rat hippocampal slices by the organic calcium channel blocker, verapamil
11. 3H]nimodipine into brain during cortical spreading depression
12. Role of calcium entry blockers in the prophylaxis of migraine
13. The genetic basis of migraine: How much do we know?
14. 2+ channels in acutely isolated hippocampal CA3 neurons of the guinea pig
15. Multiple components of calcium current in acutely dissociated dentate gyrus granule neurons
16. Amiloride selectively blocks the low threshold (T) calcium channel
17. 2+ currents in acutely isolated human hippocampal granule cells
18. Spreading depression in human slices
19. Quisqualate, kainate and NMDA can initiate spreading depression in the turtle cerebellum
20. Suppression of spreading depression of Leao in neocortex by an N-methyl-D-aspartate receptor antagonist
21. The triggering of spreading depression in the chicken retina: A pharmacological study
22. 2+ depletion enhances NMDA responses in cultured human astrocytes
23. The concept of migraine as a state of central neuronal hyperexcitability
24. Dihydropyridines interact with calcium-independent potassium currents in embryonic mammalian sensory neurons
25. Properties of the transient K+ current in acutely isolated supraoptic neurons from adult rat
26. A) by the organic calcium channel blocker verapamil in hippocampal CA1 neurons (guinea pig)
27. Extracellular free potassium and calcium during synchronous activity induced by 4-aminopyridine in the juvenile rat hippocampus
28. Role of calcium channels in spreading depression in rat hippocampal slices
29. Role of neuronal synchronizing mechanisms in the propagation of spreading depression in the in vivo hippocampus
30. Gap junctions are required for the propagation of spreading depression
31. The triggering of spreading depression in the chick retina by nicotinic receptor agonists
32. Pathophysiology of the migraine aura. The spreading depression theory
33. Transcranial Doppler evaluation of cerebral hemodynamics in migraineurs during prophylactic treatment with flunarizine
34. The effects of flunarizine in experimental models related to the pathogenesis of migraine
35. Flunarizine in common migraine: Italian cooperative trial. II. Long-term follow-up
36. Spreading depression
37. Spreading depression of Leão in rodent and human cortex
38. Ionotropic glutamate and GABA receptors in human neocortical tissue: Quantitative in vitro receptor autoradiography